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BIAL Foundation
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TI:"Final report - How do we choose a partner? Neural circuits involved in inbreeding avoidance and mate selection"
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DocumentFinal report - How do we choose a partner? Neural circuits involved in inbreeding avoidance and mate selection2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-176
Location: Arquivo PCA - Pasta 7/2008
Title:
176 - How do we choose a partner? Neural circuits involved in inbreeding avoidance and mate selection
Duration: 2009-02 - 2011-03
Researcher(s):
Susana Quelhas Lima, Léa Zinck
Institution(s): Instituto Gulbenkian de Ciência, Oeiras (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Lima, S.
Secondary author(s):
Zinck, L.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Affective and social behavior / Animal behavior / Sexual behavior

Reference code: PT/FB/BL-2008-176.01
Location: Arquivo PCA - Pasta 7/2008
Title:
Final report - How do we choose a partner? Neural circuits involved in inbreeding avoidance and mate selection
Publication year: 2011
URL:
http://www.bial.com/imagem/Bolsa176-08_03012014.pdf
Abstract/Results: ABSTRACT:
In this project we focused on assortative mate choice, that may contribute to the reproductive isolation of the two European subspecies of the house mouse, Mus musculus musculus and Mus musculus domesticus. We developed full mating and limited-contact paradigms. We found that receptive musculus females exhibit a robust preference to mate with males of the same subspecies. However, they mate readily with each male in no choice condition, and non-receptive females exhibit no preference. Moreover, when no physical contact is allowed, the female’s preference is maintained regardless of their estrous state. These experiments establish an assortative mate preference assay appropriate for the investigation of its underlying substrates. Our results highlight the interplay between the chooser´s internal state and the nature of the interaction with prospective mates and suggests that the decision is based on a comparison of the options available, rather than on an absolute preference.
We then interrogated the ontogeny of this preference, by performing adoption experiments where musculus females were raised in a domesticus environment. Our results show that female mouse mate preference has a hierarchical dependence on early postnatal life experience and the order of males encountered as an adult. Whereas females raised in their normal musculus environment display a robust homosubspecific preference, females fostered in a domesticus family prefer the first male encountered, regardless of subspecies. Thus, early life experience of musculus females, when and only when concordant with genetic self-identify, overrides sampling order effects, ensuring robust assortative choice. In the absence of this phylogenetic-ontogenetic match, simple primacy effects dominate mate preference.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Lima, S.
Secondary author(s):
Zinck, L.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Neural circuits / Mouse / Mate choice / Behavior / Sexual behavior / Mouse

Final report - How do we choose a partner? Neural circuits involved in inbreeding avoidance and mate selection

Final report - How do we choose a partner? Neural circuits involved in inbreeding avoidance and mate selection