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Final report - The diurnal pattern of cortisol secretion in relation to season in healthy participants and those with seasonal affective disorder (SAD)

2009

BIAL Foundation Archive
- BIAL Grants
  - 2006 Grants
    - 057 - The diurnal pattern of cortisol secretion in relation to season in healthy participants and those with seasonal affective disorder (SAD)
      - Final report - The diurnal pattern of cortisol secretion in relation to season in healthy participants and those with seasonal affective disorder (SAD)

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2006
Location:	Arquivo PCA - Pastas 1 a 22 /2006
Title:	2006 Grants
Start date:	2007-01 - 2013-11
Dimension/support:	22 caixas de arquivo

Reference code:	PT/FB/BL-2006-057
Location:	Arquivo PCA - Pasta 6/2006
Title:	057 - The diurnal pattern of cortisol secretion in relation to season in healthy participants and those with seasonal affective disorder (SAD)
Duration:	2007-02 - 2009-05
Researcher(s):	Angela Clow, Phil Evans, Frank Hucklebridge, Lisa Thorn
Institution(s):	Psychophysiology and Stress Research Group, Dep. of Psychology and Human and Health Sciences, University of Westminster, London (UK)
Contents:	Contents: Bursary agreement Application form Correspondence Financial report and expenditure documents Progress reports Final report 1 Article
Language:	eng
Author:	Clow, A.
Secondary author(s):	Evans, P., Hucklebridge, F., Thorn, L.
Number of reproductions:	1
Keywords:	Psychophysiology / Psychoneuroimmunology / Endocrinology / Biopsychological problems / Mental health / Mood disorders

Reference code:	PT/FB/BL-2006-057.01
Location:	Arquivo PCA - Pasta 6/2006
Title:	Final report - The diurnal pattern of cortisol secretion in relation to season in healthy participants and those with seasonal affective disorder (SAD)
Publication year:	2009
URL:	http://www.bial.com/imagem/Bolsa5706_21022014.pdf
Abstract/Results:	RESULTS: This study compared the daily pattern of cortisol secretion in winter and in summer between two groups; participants with seasonal affective disorder (SAD) and age and sex-matched healthy controls. The diurnal pattern of cortisol secretion was assessed across two consecutive days in summer, and two in winter. 52 participants completed the study with an equal number in each group. In both winter and summer, participants collected multiple saliva samples across the day to capture the cortisol awakening response (CAR) and declining levels across the day. In addition, state stress and arousal, perceived stress, anxiety and depression were assessed using validated questionnaires. The results indicated that SAD and control participants had similar psychological and cortisol profiles in summer. However, in winter, SAD participants reported greater depression, stress and anxiety compared with controls. In addition, they showed lower levels of arousal (i.e. more drowsy, tired and sluggish, less alert, active, energetic and stimulated) following awakening in the morning. The control group did not show seasonal changes in the pattern of cortisol secretion. By contrast, the CAR was significantly attenuated in SAD participants during winter months but not during the summer. There was no difference in cortisol levels during the rest of the day for SAD participants in winter. This study contributes to the understanding of the physiology of SAD and provides evidence for potential underlying pathophysiological mechanisms in SAD. It further substantiates the evidence that light therapy following awakening in the morning may be beneficial for SAD sufferers by increasing cortisol to normal levels, which in turn may alleviate symptoms.
Accessibility:	Document exists in file
Copyright/Reproduction:	By permission
Language:	eng
Author:	Clow, A.
Secondary author(s):	Evans, P., Hucklebridge, F., Thorn, L.
Document type:	Final report
Number of reproductions:	1
Indexed document:	No
Keywords:	Psychophysiology / Seasonal affective disorder / Endocrinology / Cortisol / Cortisol awakening response / Seasonal differences
Final report - The diurnal pattern of cortisol secretion in relation to season in healthy participants and those with seasonal affective disorder (SAD) Final report - The diurnal pattern of cortisol secretion in relation to season in healthy participants and those with seasonal affective disorder (SAD)