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BIAL Foundation
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TI:"Galvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis"
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DocumentGalvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2008
Location: Arquivo PCA - Pastas 1 a
Title:
2008 Grants
Start date: 2009-01

Reference code: PT/FB/BL-2008-180
Location: Arquivo PCA - Pasta 20/2008
Title:
180 - Emotional influences on psychophysiological indices of focused attention and response anticipation in social anxiety: A combined neuroimaging and electroencephalographic study
Duration: 2009-10 - 2014-07
Researcher(s):
Yoko Nagai, Hugo Critchley, Marcus Gray
Institution(s): Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, University of Sussex (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D. , Gray, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Emotion / Biopsychological problems / Mental health / Anxiety disorders / Cognitive processes / Attention / Brain structure and function

Reference code: PT/FB/BL-2008-180.02
Location: Arquivo PCA - Pasta 20/2008
Title:
Galvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis
Publication year: 2019
URL:
https://www.frontiersin.org/articles/10.3389/fneur.2019.00377/full
Abstract/Results: ABSTRACT:
Objectives: Dynamic changes in psychophysiological arousal are directly expressed in the sympathetic innervation of the skin. This activity can be measured as tonic and phasic fluctuations in electrodermal activity [Galvanic Skin Response (GSR)/skin conductance]. Biofeedback training can enable an individual to gain voluntary control over this autonomic response and its central correlates. Theoretically, control of psychophysiological arousal may be harnessed as a therapy for epilepsy, to mitigate pre-ictal states. Evidence is accumulating for the clinical efficacy of GSR biofeedback training in the management of drug resistant epilepsy. In this review, we analyse current evidence of efficacy with GSR biofeedback and evaluate the methodology of each study.
Method: We searched published literature pertaining to interventional studies of GSR biofeedback for epilepsy, through MEDLINE and Cochrane databases (1950-2018). Using percentage seizure reduction as an indicator of therapeutic efficacy induced by GSR biofeedback, we used meta-analytic methods to summarize extant findings. We also compare and contrast study design with relevance to the interpretation of outcomes.
Results: Out of 21 articles retrieved for GSR/EDA/Skin conductance biofeedback, four studies were identified as interventional trials, involving 99 patients with drug-resistant epilepsy in total. Three of these studies included a control group and a positive therapeutic effect of biofeedback was reported in each of these. The difference in seizure frequency percentage (Biofeedback-Control) was between -54.4 and -74.0% with an overall weighted mean difference of -64.3% (95% CI: -85.4 to -43.2%). The response rates (proportion of patients manifesting > 50% reduction in seizure frequency) varied from 45 to 66% across studies.
Significance: This timely evaluation highlights the potential value of GSR biofeedback therapy, and informs the optimal study design of larger scale studies that are now required to more definitively establish the utility of this non-invasive, non-pharmacological interventional approach for drug-resistant epilepsy.
Accessibility: Document exists in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Jones, C. I., Sen, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
5
Reference:
Nagai, Y., Jones, C. I., & Sen, A. (2019). Galvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis. Frontiers in Neurology, 10: 377. https://doi.org/10.3389/fneur.2019.00377
2-year Impact Factor: 2.889|2019
Times cited: 27|2024-02-12
Indexed document: Yes
Quartile: Q2
Keywords: Epilepsy / Biofeedback / Galvanic skin response / Skin conductance / Electrodermal activity / Autonomic activity / Behavioral therapy

Galvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis

Galvanic skin response (GSR)/Electrodermal/skin conductance biofeedback on epilepsy: A systematic review and meta-analysis