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BIAL Foundation
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TI:"Social-stimulus-evoked activity in the female mouse hypothalamus: Influence of the reproductive cycle "
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DocumentSocial-stimulus-evoked activity in the female mouse hypothalamus: Influence of the reproductive cycle 2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-180
Location: Arquivo PCA - Pasta 16/2010
Title:
180 - Neuronal mechanisms underlying sex hormone-dependent switching of sexual receptivity
Duration: 2011-05 - 2013-07
Researcher(s):
Kensaku Nomoto, Susana Quelhas Lima
Institution(s): Champalimaud Foundation, Lisboa (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Language: eng
Author:
Nomoto, K.
Secondary author(s):
Lima, S.
Number of reproductions:
1
Keywords:
Psychophysiology / Affective and social behavior / Animal behavior / Sexual behavior / Brain structure and function

Reference code: PT/FB/BL-2010-180.03
Location: Arquivo PCA - Pasta 16/2010
Title:
Social-stimulus-evoked activity in the female mouse hypothalamus: Influence of the reproductive cycle
Publication year: 2012
URL:
http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=8f618c5a-55eb-4fdc-9857-ba3eeb69220a&cKey=8496f7fc-39f7-48ce-ad0e-ac19bc1fbac6&mKey=%7b70007181-01C9-4DE9-A0A2-EEBFA14CD9F1%7d
Abstract/Results: ABSTRACT:
In many mammalian species, ovarian hormones fluctuate during the reproductive cycle, heavily influencing female behavior. In rodents, changes in sexual receptivity are one of the most fundamental changes across the reproductive cycle. While, for instance, a female rodent is sexually receptive during the proestrous phase, she rejects copulation during all other phases of the reproductive cycle. It is well accepted that the ventromedial hypothalamus (VMH) plays a critical role in the control of female sexual behavior. However it is poorly understood how the activity of VMH neurons is coordinated and mediates behavioral changes across the reproductive cycle. To address this issue, we performed extracellular single-unit recording experiments in behaving female mice across the reproductive cycle. The test animal was allowed to interact freely with the stimulus animals that were introduced into the arena sequentially. In agreement with a previous study in male mice, we found VMH neurons that significantly responded with increased or decreased activity during social investigation compared to the activity during the control period. We classified VMH neurons based on their response pattern against the male stimuli: excited, inhibited, or no response. Our results showed that the proportion of male-inhibited neurons during the proestrous phase (7/20, 35%) was higher than those during the estrous and diestrous phases (4/29, 14% and 4/26, 15%, respectively). These preliminary results suggest that changes in the balance of excitation and inhibition in VMH neurons may underlie behavioral changes across the reproductive cycle.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nomoto, K.
Secondary author(s):
Lima, S.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Nomoto, K., & Lima, S. (2012). Social-stimulus-evoked activity in the female mouse hypothalamus: Influence of the reproductive cycle. Program No. 401.09/FFF47. Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online. Abstract retrieved from http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=8f618c5a-55eb-4fdc-9857-ba3eeb69220a&cKey=8496f7fc-39f7-48ce-ad0e-ac19bc1fbac6&mKey=%7b70007181-01C9-4DE9-A0A2-EEBFA14CD9F1%7d
Indexed document: No
Keywords: Hypothalamus / Sexual behavior / Electrophysiology