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BIAL Foundation
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TI:"Unveiling the role of oxytocin-like peptides in the regulation of the zebrafish social behavior"
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DocumentUnveiling the role of oxytocin-like peptides in the regulation of the zebrafish social behavior2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-339
Location: BF-GMS
Title:
339 - Neural mechanisms of social cognition in zebrafish
Duration: 2015-05 - 2019-11
Researcher(s):
Ana Rita Silva Martins Nunes
Institution(s): Instituto Gulbenkian de Ciencia, Oeiras (Portugal)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress Report
Final Report
Articles
Language: eng
Author:
Nunes, A. R.
Number of reproductions:
1
Keywords:
Social cognition / Social dominance / Oxytocin / Biological motion / Psychophysiology

Reference code: PT/FB/BL-2014-339.07
Location: BF-GMS
Title:
Unveiling the role of oxytocin-like peptides in the regulation of the zebrafish social behavior
Publication year: 2016
Abstract/Results:
ABSTRACT:
An elementary cognitive ability for social behaviour is the recognition of other behavioral agents in the environment. Point lights placed on the main joints of a walking person or even simple visual
displays (e.g. moving geometric-shapes) can originate a high-level percept of animacy. This ability is conserved across species and is critical for filial attachment, detection of predators, and perception
of social dominance. We aim to characterize the neural mechanisms underlying animacy, and to test if this ability is regulated by oxytocin-like peptides (oxytocin in mammals, isotocin in fish), which are a family of neuromodulators implicated in the regulation of social behavior across vertebrates.
Using zebrafish as an organism model, we developed new genetic tools that allow us to study the role of oxytocin in social behavior. We first characterized the ontogeny of sociality, measured by a
robust shoal preference test, and showed that it emerges around the third-week post fertilization. To explore how oxytocin affects the acquisition and modulation of sociality, we have specifically
perturbed oxytocinergic neuronal circuits and examined how loss of function of these neurons during development modifies social behavior. We observed that ablation of these neurons at a critical developmental period, but not during adulthood, significantly reduces shoal preference. Next, we found preliminary evidences for zebrafish ability to discriminate animacy cues, namely acceleration.
In the near future we plan to explore the role of oxytocin-like peptides in the regulation of animacy detection.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nunes, A. R.
Secondary author(s):
Correia, L., Levkowitz, G., Oliveira, R.
Document type:
Unpublished abstract
Number of reproductions:
1
Reference:
Nunes, A. R., Correia, L., Levkowitz, G., & Oliveira, R. (2016). Unveiling the role of oxytocin-like peptides in the regulation of the zebrafish social behavior. Paper presented at the Rovereto Workshop on Cognition and Evolution V edition, CIMeC. Center for Mind/Brain Sciences, University of Trento, Italy.
Indexed document: No
Keywords: Zebrafish / Oxytocin