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DocumentCharacterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories2016-032019-03

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

DocumentFalse memory susceptibility in coma survivors with and without a near-death experience2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-02
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
False memory susceptibility in coma survivors with and without a near-death experience
Publication year: 2016
URL:
https://link.springer.com/article/10.1007/s00426-017-0855-9
Abstract/Results: ABSTRACT:
It has been postulated that memories of near-death experiences (NDEs) could be (at least in part) reconstructions based on experiencers’ (NDErs) previous knowledge and could be built as a result of the individual’s attempt to interpret the confusing experience. From the point of view of the experiencer, NDE memories are perceived as being unrivalled memories due to its associated rich phenomenology. However, the scientific literature devoted to the cognitive functioning of NDErs in general, and their memory performance in particular, is rather limited. This study examined NDErs’ susceptibility to false memories using the Deese–Roediger–McDermott (DRM) paradigm. We included 20 NDErs who reported having had their experience in the context of a life-threatening event (Greyson NDE scale total score =7/32) and 20 volunteers (matched for age, gender, education level, and time since brain insult) who reported a life-threatening event but without a NDE. Both groups were presented with DRM lists for a recall task during which they were asked to assign “Remember/Know/Guess” judgements to any recalled response. In addition, they were later asked to complete a post-recall test designed to obtain estimates of activation and monitoring of critical lures. Results demonstrated that NDErs and volunteers were equally likely to produce false memories, but that NDErs recalled them more frequently associated with compelling illusory recollection. Of particular interest, analyses of activation and monitoring estimates suggest that NDErs and volunteers groups were equally likely to think of critical lures, but source monitoring was less successful in NDErs compared to volunteers.
Accessibility: Document exists in file
Copyright/Reproduction:
By permision
Language:
eng
Author:
Martial, C.
Secondary author(s):
Charland-Verville, V., Dehon, H., Laureys, S.
Document type:
Article
Reference:
Martial, C., Charland-Verville, V., Dehon, H., & Laureys, S. (2017). False memory susceptibility in coma survivors with and without a near-death experience. Psychological Research-Psychologishe Forschung, 82(4), 806-818. doi: 10.1007/s00426-017-0855-9
2-year Impact Factor: 2.329|2017
Times cited: 3|2020-03-31
Indexed document: Yes
Quartile: Q2
Keywords: Near-death experience / Memory

DocumentIntensity and memory characteristics of near-death experiences2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-03
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Intensity and memory characteristics of near-death experiences
Publication year: 2017
URL:
http://www.sciencedirect.com/science/article/pii/S1053810016303804?via%3Dihub
Abstract/Results: ABSTRACT:
Memories of Near-Death Experiences (NDEs) seem to be very detailed and stable over time. At present, there is still no satisfactory explanation for the NDEs’ rich phenomenology. Here we compared phenomenological characteristics of NDE memories with the reported experience’s intensity. We included 152 individuals with a self-reported “classical” NDE (i.e. occurring in life-threatening conditions). All participants completed a mailed questionnaire that included a measure of phenomenological characteristics of memories (the Memory Characteristics Questionnaire; MCQ) and a measure of NDE’s intensity (the Greyson NDE scale). Greyson NDE scale total score was positively correlated with MCQ total score, suggesting that participants who described more intense NDEs also reported more phenomenological memory characteristics of NDE. Using MCQ items, our study also showed that NDE’s intensity is associated in particular with sensory details, personal importance and reactivation frequency variables.
Accessibility: Document does not exist in file
Language:
eng
Author:
Martial, C.
Secondary author(s):
Charland-Verville, V., Cassol. H., Didone, V., Van der Liden, M., Laureys, S.
Document type:
Article
Reference:
Martial, C., Charland-Verville, V., Cassol. H., Didone, V., Van der Liden, M., & Laureys, S. (2017). Intensity and memory characteristics of near-death experiences. Consciousness and Cognition, 56, 120-127. doi: 10.1016/j.concog.2017.06.018
2-year Impact Factor: 2.272|2017
Times cited: 5|2020-03-31
Indexed document: Yes
Quartile: Q2
Keywords: Near-death experience / Memory / Intensity / Phenomenological characteristics / Greyson NDE scale / Memory Characteristics Questionnaire

DocumentTemporality of features in near-death experience narratives2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-05
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Temporality of features in near-death experience narratives
Publication year: 2017
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469194/
Abstract/Results: ABSTRACT:
BACKGROUND:
After an occurrence of a Near-Death Experience (NDE), Near-Death Experiencers (NDErs) usually report extremely rich and detailed narratives. Phenomenologically, a NDE can be described as a set of distinguishable features. Some authors have proposed regular patterns of NDEs, however, the actual temporality sequence of NDE core features remains a little explored area.
OBJECTIVES:
The aim of the present study was to investigate the frequency distribution of these features (globally and according to the position of features in narratives) as well as the most frequently reported temporality sequences of features.
METHODS:
We collected 154 French freely expressed written NDE narratives (i.e., Greyson NDE scale total score = 7/32). A text analysis was conducted on all narratives in order to infer temporal ordering and frequency distribution of NDE features.
RESULTS:
Our analyses highlighted the following most frequently reported sequence of consecutive NDE features: Out-of-Body Experience, Experiencing a tunnel, Seeing a bright light, Feeling of peace. Yet, this sequence was encountered in a very limited number of NDErs.
CONCLUSION:
These findings may suggest that NDEs temporality sequences can vary across NDErs. Exploring associations and relationships among features encountered during NDEs may complete the rigorous definition and scientific comprehension of the phenomenon.
Accessibility: Document exists in file
Language:
eng
Author:
Martial, C.
Secondary author(s):
Cassol, H., Antonopoulos, G., Charliers, T., Heros, J., Donneau, A.-F., Charland-Verville, V., Laureys, S.
Document type:
Article
Reference:
Martial, C., Cassol, H., Antonopoulos, G., Charliers, T., Heros, J., Donneau, A.-F., Charland-Verville, V., & Laureys, S. (2017). Temporality of features in near-death experience narratives. Frontiers in Human Neuroscience, 11: 311. doi: 10.3389/fnhum.2017.00311
2-year Impact Factor: 2.871|2017
Times cited: 10|2020-03-31
Indexed document: Yes
Quartile: Q2
Keywords: Near-death experience / Narrative / Temporality / Feature / Sequence / Text analysis

Temporality of features in near-death experience narratives

Temporality of features in near-death experience narratives

DocumentThe exploration of the content of memories after coma2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-03
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
The exploration of the content of memories after coma
Publication year: 2016
Abstract/Results:
ABSTRACT:
After recovering from a coma, patients can sometimes report vivid perceptions and memories of their period on seemingly unconsciousness referred to as “Near-Death Experiences” (NDEs). In addition to the ill-described relation between the NDEs and the precipitating factors, the reliability of NDEs accounts remains controversial.
STUDY 1: We began by testing the hypothesis stating that that these memories could result from a blend between imagined and real events surrounding the period of unconsciousness. These memories could be comparable to an imagined event in terms of phenomenological characteristics. Using the Memory Characteristics Questionnaire and the Greyson NDE scale we compared NDE memories with other coma memories as well as real-life and imagined memories. Our results showed that NDEs memories contain more phenomenological content than any kind of memory of real and imagined events. NDEs cannot be considered as imagined events but seem rather seem to be unique and unrivaled, as described by experiencers.
STUDY 2: To date, no studies have tried to correlate the etiology of the possible brain damage with NDEs core features. Therefore, we aimed at assessing whether the cause of the context in which the NDE occurred (after a coma/life-threatening event versus a non-life-threatening event) would influence the reported NDE’s intensity and content. Our analyses failed to show any differences between groups for the context of occurrence. However, the overall NDE core features’ frequencies were higher in our retrospective anoxic cohort when compared to historical published prospective data suggesting that NDE reports might suffer from memory reconstructions.
STUDY 3: To further investigate the possible influence of the brain lesion site, we recruited a clear and medically documented cohort of locked-in syndrome (LIS) patients who reported NDEs after surviving a coma caused by brainstem lesion at the pontine level. The “LIS NDEs” group was compared to a group of “classical NDEs” that have occurred after supratentorial lesions. Interestingly, although memories of NDEs are classically recounted as emotionally positive events, it was one of the least reported features for the “LIS NDEs” group. They also had a tendency towards reporting greater life review and lesser joy. Lesser positive emotions and autobiographical memory flashbacks in the “LIS NDEs” could be linked to an altered connectivity in (para)limbic systems secondary to the acute pontine brainstem dysfunction.
STUDY 4: In parallel with the hypothesis stating that the strong belief or the awareness of being dead associated with an altered state of consciousness could suffice to trigger a NDE, we then aimed at exploring the brain metabolism of a patient who was convinced he was dead (patient with Cotard’s syndrome). Results identified hypometabolic regions in the “default mode network”, known to be critical for conscious self-awareness. These findings suggest that the significant modulation of thought and experience, revealed by Cotard’s delusion, reflects a profound disturbance in brain regions responsible for “core consciousness” and our abiding sense of self.
By bridging the data from psychology and neurology, this thesis work will be integrated for the enrichment of an explicative theory for the NDE phenomenon. To achieve a more rigorous definition and comprehension of the phenomenon, we propose to experimentally induce NDEs along with closely assess the experiencers’ subjective first-person phenomenal experience in parallel with state-of-the art brain monitoring in a controlled laboratory setting.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Charland-Verville, V.
Document type:
Doctoral thesis
Reference:
Charland-Verville, V. (2016). The exploration of the content of memories after coma (Unpublished doctoral thesis). Faculty of Medicine, University of Liege, Belgium.
Indexed document: No
Keywords: Near-death experience / Memory

DocumentInvestigating DRM false memories susceptibility in near-death experiencers2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-04
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Investigating DRM false memories susceptibility in near-death experiencers
Publication year: 2016
URL:
http://www.asszisztencia.hu/icom/program_download.htm
Abstract/Results: ABSTRACT:
Literature devoted to the cognitive functioning of individuals who lived a near-death experience (NDErs) is very limited. This study examines their susceptibility to false memories using the Deese–Roediger–McDermott paradigm (DRM; Roediger&McDermott, 1995). Specifically, 20 NDErs and 19 healthy volunteers matched on age, education and time since accident were presented with DRM lists for a recall task during which they were asked to assign “Remember/Know/Guess” judgements (Tulving, 1985) to their responses. Results showed that NDErs and volunteers were equally likely to recall studied items, to falsely recall critical lures and obtained similar rates of associated illusory recollection. These findings are discussed in light of the current theories of false memory production and accounts of NDE.
Accessibility: Document exists in file
Language:
eng
Author:
Martial, C.
Secondary author(s):
Charland-Verville, V., Dehon, H., Laureys, S.
Document type:
Abstract book
Reference:
Martial, C., Charland-Verville, V., Dehon, H., & Laureys, S. (2016). Investigating DRM false memories susceptibility in near-death experiencers. Abstract book of the 6th International Conference on Memory, Budapest, Hungary (p.79).
Indexed document: No
Keywords: Near-death experience / Deese-Roediger-Mcdermott (DRM) paradigm / False memories

Investigating DRM false memories susceptibility in near-death experiencers

Investigating DRM false memories susceptibility in near-death experiencers

DocumentMultifaceted brain networks reconfiguration in disorders of consciousness uncovered by co-activation patterns2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-12
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Multifaceted brain networks reconfiguration in disorders of consciousness uncovered by co-activation patterns
Publication year: 2018
URL:
http://onlinelibrary.wiley.com/doi/10.1002/hbm.23826/abstract
Abstract/Results: ABSTRACT:
INTRODUCTION
Given that recent research has shown that functional connectivity is not a static phenomenon, we aim to investigate the dynamic properties of the default mode network's (DMN) connectivity in patients with disorders of consciousness.
METHODS
Resting-state fMRI volumes of a convenience sample of 17 patients in unresponsive wakefulness syndrome (UWS) and controls were reduced to a spatiotemporal point process by selecting critical time points in the posterior cingulate cortex (PCC). Spatial clustering was performed on the extracted PCC time frames to obtain 8 different co-activation patterns (CAPs). We investigated spatial connectivity patterns positively and negatively correlated with PCC using both CAPs and standard stationary method. We calculated CAPs occurrences and the total number of frames.
RESULTS
Compared to controls, patients showed (i) decreased within-network positive correlations and between-network negative correlations, (ii) emergence of “pathological” within-network negative correlations and between-network positive correlations (better defined with CAPs), and (iii) “pathological” increases in within-network positive correlations and between-network negative correlations (only detectable using CAPs). Patients showed decreased occurrence of DMN-like CAPs (1–2) compared to controls. No between-group differences were observed in the total number of frames
CONCLUSION
CAPs reveal at a more fine-grained level the multifaceted spatial connectivity reconfiguration following the DMN disruption in UWS patients, which is more complex than previously thought and suggests alternative anatomical substrates for consciousness. BOLD fluctuations do not seem to differ between patients and controls, suggesting that BOLD response represents an intrinsic feature of the signal, and therefore that spatial configuration is more important for consciousness than BOLD activation itself.
Accessibility: Document does not exist in file
Language:
eng
Notes:
Di Perri C1,2, Amico E1,3,4, Heine L1, Annen J1, Martial C1, Larroque SK1, Soddu A5, Marinazzo D3, Laureys S1.
Author: Di Perri, C.
Secondary author(s):
Amico, E., Heine, L., Annen, J., Martial, C., Larroque, S. K., Soddu, A., Marinazzo, D., Laureys, S.
Document type:
Article
Reference:
Di Perri, C., Amico, E., Heine, L., Annen, J., Martial, C., Larroque, S. K., Soddu, A., Marinazzo, D., & Laureys, S. (2018). Multifaceted brain networks reconfiguration in disorders of consciousness uncovered by co-activation patterns. Human Brain Mapping,39(1), 89-103. doi: 10.1002/hbm.23826
2-year Impact Factor: 4.554|2018
Times cited: 5|2020-03-31
Indexed document: Yes
Quartile: Q1
Keywords: Disorders of consciousness / Default mode network

DocumentSpasticity management in disorders of consciousness2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-06
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Spasticity management in disorders of consciousness
Publication year: 2017
URL:
http://www.mdpi.com/2076-3425/7/12/162/htm
Abstract/Results: ABSTRACT:
BACKGROUND:
Spasticity is a motor disorder frequently encountered after a lesion involving the central nervous system. It is hypothesized to arise from an anarchic reorganization of the pyramidal and parapyramidal fibers and leads to hypertonia and hyperreflexia of the affected muscular groups. While this symptom and its management is well-known in patients suffering from stroke, multiple sclerosis or spinal cord lesion, little is known regarding its appropriate management in patients presenting disorders of consciousness after brain damage.
OBJECTIVES:
Our aim was to review the occurrence of spasticity in patients with disorders of consciousness and the therapeutic interventions used to treat it. Methods: We conducted a systematic review using the PubMed online database. It returned 157 articles. After applying our inclusion criteria (i.e., studies about patients in coma, unresponsive wakefulness syndrome or minimally conscious state, with spasticity objectively reported as a primary or secondary outcome), 18 studies were fully reviewed.
RESULTS:
The prevalence of spasticity in patients with disorders of consciousness ranged from 59% to 89%. Current treatment options include intrathecal baclofen and soft splints. Several treatment options still need further investigation; including acupuncture, botulin toxin or cortical activation by thalamic stimulation.
CONCLUSION:
The small number of articles available in the current literature highlights that spasticity is poorly studied in patients with disorders of consciousness although it is one of the most common motor disorders. While treatments such as intrathecal baclofen and soft splints seem effective, large randomized controlled trials have to be done and new therapeutic options should be explored.
Accessibility: Document exists in file
Language:
eng
Author:
Martens, G.
Secondary author(s):
Laureys, S., Thibaut, A.
Document type:
Article
Reference:
Martens, G., Laureys, S., & Thibaut, A. (2017). Spasticity management in disorders of consciousness. Brain Sciences, 7(12), 162. doi:10.3390/brainsci7120162
2-year Impact Factor: 2.786|2018
Impact factor notes: Impact factor only for 2018
Times cited: 7|2020-04-02
Indexed document: Yes
Quartile: Q3
Keywords: Spasticity / Pain / Upper motor neuron syndrome / Disorders of consciousness / Brain injury / Treatment

Spasticity management in disorders of consciousness

Spasticity management in disorders of consciousness

DocumentNear-death experiences: actual considerations2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-07
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Near-death experiences: actual considerations
Publication year: 2017
URL:
https://link.springer.com/chapter/10.1007/978-3-319-55964-3_14
Abstract/Results: ABSTRACT:
The notion that death represents a passing to an afterlife, where we are reunited with loved ones and live eternally in a utopian paradise, is common in the anecdotal reports of people who have encountered a “near-death experience” (NDE). These experiences are usually portrayed as being extremely pleasant including features such as a feeling of peacefulness, the vision of a dark tunnel leading to a brilliant light, the sensation of leaving the body, or the experience of a life review. NDEs are increasingly being reported as a clearly identifiable physiological and psychological reality of clinical and scientific significance. The definition and causes of the phenomenon as well as the identification of NDE experiencers are still matters of debate. The phenomenon has been thoroughly portrayed by the media, but the science of NDEs is rather recent and still lacking of rigorous experimental data and reproducible controlled experiments. It seems that the most appropriate theories to explain the phenomenon tend to integrate both psychological and neurobiological mechanisms. The paradoxical dissociation between the richness and intensity of the memory, probably occurring during a moment of brain dysfunction, offers a unique opportunity to better understand the neural correlates of consciousness. In this chapter, we will attempt to describe NDEs and the methods to identify them. We will also briefly discuss the NDE experiencers’ characteristics. We will then address the main current explicative models and the science of NDEs.
Accessibility: Document does not exists in file
Language:
eng
Author:
Charland-Verville, V.
Secondary author(s):
Martial, C., Cassol, H., Laureys, S.
Document type:
Book chapter
Reference:
Charland-Verville, V., Martial, C., Cassol, H., & Laureys, S. (2017). Near-death experiences: actual considerations. In C. Schnakers & S. Laureys (Eds.), Coma and Disorders of Consciousness (2nd ed.) (pp. 235-263). Cham, Switzerland: Springer International Publishing AG. doi: 10.1007/978-3-319-55964-3
Indexed document: Yes
Keywords: Near-death experience / Consciousness / Coma

DocumentQualitative thematic analysis of the phenomenology of near-death experiences2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-08
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Qualitative thematic analysis of the phenomenology of near-death experiences
Publication year: 2018
URL:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193001
Abstract/Results: ABSTRACT:
Near-death experiences (NDEs) refer to profound psychological events that can have an important impact on the experiencers' (NDErs) lives. Previous studies have shown that NDEs memories are phenomenologically rich. In the present study, we therefore aimed to extract the common themes (referred to as "features" in the NDE literature) reported by NDErs by analyzing all the concepts stored in the narratives of their experiences. A qualitative thematic analysis has been carried out on 34 cardiac arrest survivors' NDE narratives. Our results shed the light on the structure of the narratives by identifying 10 "time-bounded" themes which refer to isolated events encountered during the NDE and 1 "transversal" theme which characterizes the whole narrative and generally appears as a retrospective comment of self-reflection on the experience. The division of narratives into themes provides us with detailed information about the vocabulary used by NDErs to describe their experience. This established thematic method enables a rigorous description of the phenomenon, ensuring the inclusion of all self-reported manifestations of themes in narratives.
Accessibility: Document exists in file
Language:
eng
Author:
Cassol, H.
Secondary author(s):
Pétré, B., Degrange, S., Martial, C., Charland-Verville, V., Lallier, F., Bragard, I., Guillaume, M., Laureys, S.
Document type:
Article
Reference:
Cassol, H., Pétré, B., Degrange, S., Martial, C., Charland-Verville, V., Lallier, F., Bragard, I., Guillaume, M., & Laureys, S. (2018). Qualitative thematic analysis of the phenomenology of near-death experiences. PLoS One,13(2): e0193001. doi: 10.1371/journal.pone.0193001
2-year Impact Factor: 2.776|2018
Times cited: 17|2020-04-02
Indexed document: Yes
Quartile: Q1
Keywords: Near-death experience / Narratives / Qualitative methodology

Qualitative thematic analysis of the phenomenology of near-death experiences

Qualitative thematic analysis of the phenomenology of near-death experiences

DocumentRandomized controlled trial of home-based 4-week tDCS in chronic minimally conscious state2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-09
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Randomized controlled trial of home-based 4-week tDCS in chronic minimally conscious state
Publication year: 2018
URL:
https://www.brainstimjrnl.com/article/S1935-861X(18)30146-3/fulltext
Abstract/Results: ABSTRACT:
BACKGROUND:
Patients with chronic disorders of consciousness face a significant lack of treatment options.
OBJECTIVE:
We aimed at investigating the feasibility and the behavioral effects of home-based transcranial direct current stimulation (tDCS), applied by relatives or caregivers, in chronic patients in minimally conscious state (MCS).
METHODS:
Each participant received, in a randomized order, 20 sessions of active and 20 sessions of sham tDCS applied over the prefrontal cortex for 4 weeks; separated by 8 weeks of washout. Level of consciousness was assessed using the Coma Recovery Scale-Revised before the first stimulation (baseline), at the end of the 20 tDCS sessions (direct effects) and 8 weeks after the end of each stimulation period (long-term effects). Reported adverse events and data relative to the adherence (i.e., amount of sessions effectively received) were collected as well.
RESULTS:
Twenty-seven patients completed the study and 22 patients received at least 80% of the stimulation sessions. All patients tolerated tDCS well, no severe adverse events were noticed after real stimulation and the overall adherence (i.e., total duration of stimulation) was good. A moderate effect size (0.47 and 0.53, for modified intention to treat and per protocol analysis, respectively) was observed at the end of the 4 weeks of tDCS in favor of the active treatment.
CONCLUSIONS:
We demonstrated that home-based tDCS can be used adequately outside a research facility or hospital by patients' relatives or caregivers. In addition, 4 weeks of tDCS moderately improved the recovery of signs of consciousness in chronic MCS patients.
Accessibility: Document exits in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Martens, G.
Secondary author(s):
Lejeune, N., O'Brien, A. , Fregni, F., Martial, C., Wannez, S., Laureys, S., Thibaut, A.
Document type:
Article
Reference:
Martens, G., Lejeune, N., O'Brien, A., Fregni, F., Martial, C., Wannez, S., Laureys, S., & Thibaut, A. (2018). Randomized controlled trial of home-based 4-week tDCS in chronic minimally conscious state. Brain Stimulation, 11(5), 982-990. doi: 10.1016/j.brs.2018.04.021
2-year Impact Factor: 6.919|2018
Times cited: 12|2020-04-02
Indexed document: Yes
Quartile: Q1
Keywords: Consciousness / Minimally conscious state / Transcranial direct current stimulation (tDCS) / Traumatic brain injury

DocumentUltra-slow mechanical stimulation of olfactory epithelium modulates consciousness by slowing cerebral rhythms in humans2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-10
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Ultra-slow mechanical stimulation of olfactory epithelium modulates consciousness by slowing cerebral rhythms in humans
Publication year: 2018
URL:
https://www.nature.com/articles/s41598-018-24924-9
Abstract/Results: ABSTRACT:
The coupling between respiration and neural activity within olfactory areas and hippocampus has recently been unambiguously demonstrated, its neurophysiological basis sustained by the well-assessed mechanical sensitivity of the olfactory epithelium. We herein hypothesize that this coupling reverberates to the whole brain, possibly modulating the subject's behavior and state of consciousness. The olfactory epithelium of 12 healthy subjects was stimulated with periodical odorless air-delivery (frequency 0.05 Hz, 8 s on, 12 off). Cortical electrical activity (High Density-EEG) and perceived state of consciousness have been studied. The stimulation induced i) an enhancement of delta-theta EEG activity over the whole cortex mainly involving the Limbic System and Default Mode Network structures, ii) a reversal of the overall information flow directionality from wake-like postero-anterior to NREM sleep-like antero-posterior, iii) the perception of having experienced an Altered State of Consciousness. These findings could shed further light via a neurophenomenological approach on the links between respiration, cerebral activity and subjective experience, suggesting a plausible neurophysiological basis for interpreting altered states of consciousness induced by respiration-based meditative practices.
Accessibility: Document exists in file
Language:
eng
Author:
Piarulli, A.
Secondary author(s):
Zaccaro, A., Laurino, M., Menicucci, D., De Vito, A., Bruschini, L., Berrettini, S., Bergamasco, M., Laureys, S., Gemignani, A.
Document type:
Article
Reference:
Piarulli, A., Zaccaro, A., Laurino, M., Menicucci, D., De Vito, A., Bruschini, L., Berrettini, S., Bergamasco, M., Laureys, S., & Gemignani, A. (2018). Ultra-slow mechanical stimulation of olfactory epithelium modulates consciousness by slowing cerebral rhythms in humans. Scientific Reports, 8: 6581. doi: 10.1038/s41598-018-24924-9
2-year Impact Factor: 4.011|2018
Times cited: 8|2020-04-02
Indexed document: Yes
Quartile: Q1

Ultra-slow mechanical stimulation of olfactory epithelium modulates consciousness by slowing cerebral rhythms in humans

Ultra-slow mechanical stimulation of olfactory epithelium modulates consciousness by slowing cerebral rhythms in humans

DocumentTheta network centrality correlates with tDCS response in disorders of consciousness2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-11
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Theta network centrality correlates with tDCS response in disorders of consciousness
Publication year: 2018
URL:
https://www.brainstimjrnl.com/article/S1935-861X(18)30304-8/fulltext
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Thibaut, A.
Secondary author(s):
Chennu, S., Chatelle, C., Martens, G., Annen, J., Cassol, H., Laureys, S.
Document type:
Article
Reference:
Thibaut, A., Chennu, S., Chatelle, C., Martens, G., Annen, J., Cassol, H., & Laureys, S. (2018). Theta network centrality correlates with tDCS response in disorders of consciousness. Brain Stimulation, 11, 1407-1409. doi: 10.1016/j.brs.2018.09.002
2-year Impact Factor: 6.919|2018
Times cited: 4|2020-04-02
Indexed document: Yes
Quartile: Q1
Keywords: Coma / Disorders of consciousness / Electroencephalography (EEG) / Connectivity / Transcranial direct current stimulation (tDCS)

DocumentBCI performance and brain metabolism profile in severely brain-injured patients 2 without response to command at bedside2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-13
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
BCI performance and brain metabolism profile in severely brain-injured patients 2 without response to command at bedside
Publication year: 2018
URL:
https://www.frontiersin.org/articles/10.3389/fnins.2018.00370/full
Abstract/Results: ABSTRACT:
Detection and interpretation of signs of "covert command following" in patients with disorders of consciousness (DOC) remains a challenge for clinicians. In this study, we used a tactile P3-based BCI in 12 patients without behavioral command following, attempting to establish "covert command following." These results were then confronted to cerebral metabolism preservation as measured with glucose PET (FDG-PET). One patient showed "covert command following" (i.e., above-threshold BCI performance) during the active tactile paradigm. This patient also showed a higher cerebral glucose metabolism within the language network (presumably required for command following) when compared with the other patients without "covert command-following" but having a cerebral glucose metabolism indicative of minimally conscious state. Our results suggest that the P3-based BCI might probe "covert command following" in patients without behavioral response to command and therefore could be a valuable addition in the clinical assessment of patients with DOC.
Accessibility: Document exists in file
Language:
eng
Author:
Annen, J.
Secondary author(s):
Blandiaux, S., Lejeune, N., Bahri, M. A., Thibaut, A., Cho, W., Guger, C., Chatelle, C., Laureys, S.
Document type:
Article
Reference:
Annen, J., Blandiaux, S., Lejeune, N., Bahri, M. A., Thibaut, A., Cho, W., Guger, C., Chatelle, C., & Laureys, S. (2018). BCI performance and brain metabolism profile in severely brain-injured patients 2 without response to command at bedside. Frontiers in Neuroscience, 12, 370. doi: 10.3389/fnins.2018.00370
2-year Impact Factor: 3.648|2018
Times cited: 3|2020-04-02
Indexed document: Yes
Quartile: Q2
Keywords: FDG-PET / P3 / Brain computer interface / Consciousness / Covert command following / Disorders of consciousness

BCI performance and brain metabolism profile in severely brain-injured patients 2 without response to command at bedside

BCI performance and brain metabolism profile in severely brain-injured patients 2 without response to command at bedside

DocumentRegional brain volumetry and brain function in severely brain-injured patients2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-14
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Regional brain volumetry and brain function in severely brain-injured patients
Publication year: 2018
URL:
https://onlinelibrary.wiley.com/doi/abs/10.1002/ana.25214
Abstract/Results: ABSTRACT:
OBJECTIVE
The relationship between residual brain tissue in patients with disorders of consciousness (DOC) and the clinical condition is unclear. This observational study aimed to quantify gray (GM) and white matter (WM) atrophy in states of (altered) consciousness.
METHODS
Structural T1-weighted magnetic resonance images were processed for 102 severely brain-injured and 52 healthy subjects. Regional brain volume was quantified for 158 (sub)cortical regions using Freesurfer. The relationship between regional brain volume and clinical characteristics of patients with DOC and conscious brain-injured patients was assessed using a linear mixed-effects model. Classification of patients with unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS) using regional volumetric information was performed and compared to classification using cerebral glucose uptake from fluorodeoxyglucose positron emission tomography. For validation, the T1-based classifier was tested on independent datasets.
RESULTS
Patients were characterized by smaller regional brain volumes than healthy subjects. Atrophy occurred faster in UWS compared to MCS (GM) and conscious (GM and WM) patients. Classification was successful (misclassification with leave-one-out cross-validation between 2% and 13%) and generalized to the independent data set with an area under the receiver operator curve of 79% (95% confidence interval [CI; 67-91.5]) for GM and 70% (95% CI [55.6-85.4]) for WM.
INTERPRETATION
Brain volumetry at the single-subject level reveals that regions in the default mode network and subcortical gray matter regions, as well as white matter regions involved in long range connectivity, are most important to distinguish levels of consciousness. Our findings suggest that changes of brain structure provide information in addition to the assessment of functional neuroimaging and thus should be evaluated as well.
Accessibility: Document exists in file
Copyright/Reproduction:
By permisison
Language:
eng
Author:
Annen, J.
Secondary author(s):
Frasso, G., Heine, L., Di Perri, C., Martial, C., Antonopoulous, G., Aubinet, C., Cassol, H., Laureys, S.
Document type:
Article
Reference:
Annen, J., Frasso, G., Heine, L., Di Perri, C., Martial, C., Antonopoulous, G., Aubinet, C., Cassol, H., Laureys, S., & Coma Science Group Collaborators (2018). Regional brain volumetry and brain function in severely brain-injured patients. Annals of Neurology, 83(4), 842–853.
2-year Impact Factor: 9.496|2018
Times cited: 7|2020-04-02
Indexed document: Yes
Quartile: Q1
Keywords: Gray matter / White matter / Unresponsive wakefulness syndrome (UWS) / Minimally conscious state (MCS)

DocumentClinical subcategorization of minimally conscious state according to resting functional connectivity2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-15
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Clinical subcategorization of minimally conscious state according to resting functional connectivity
Publication year: 2018
URL:
https://onlinelibrary.wiley.com/doi/abs/10.1002/hbm.24303
Abstract/Results: ABSTRACT:
Patients in minimally conscious state (MCS) have been subcategorized in MCS plus and MCS minus, based on command-following, intelligible verbalization or intentional communication. We here aimed to better characterize the functional neuroanatomy of MCS based on this clinical subcategorization by means of resting state functional magnetic resonance imaging (fMRI). Resting state fMRI was acquired in 292 MCS patients and a seed-based analysis was conducted on a convenience sample of 10 MCS plus patients, 9 MCS minus patients and 35 healthy subjects. We investigated the left and right frontoparietal networks (FPN), auditory network, default mode network (DMN), thalamocortical connectivity and DMN between-network anticorrelations. We also employed an analysis based on regions of interest (ROI) to examine interhemispheric connectivity and investigated intergroup differences in gray/white matter volume by means of voxel-based morphometry. We found a higher connectivity in MCS plus as compared to MCS minus in the left FPN, specifically between the left dorso-lateral prefrontal cortex and left temporo-occipital fusiform cortex. No differences between patient groups were observed in the auditory network, right FPN, DMN, thalamocortical and interhemispheric connectivity, between-network anticorrelations and gray/white matter volume. Our preliminary group-level results suggest that the clinical subcategorization of MCS may involve functional connectivity differences in a language-related executive control network. MCS plus and minus patients are seemingly not differentiated by networks associated to auditory processing, perception of surroundings and internal awareness/self-mentation, nor by interhemispheric integration and structural brain damage.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Aubinet, A.
Secondary author(s):
Larroque, S., Heine, L., Martial, C., Majerus, S., Laureys, S., Di Perri, C.
Document type:
Article
Reference:
Aubinet, A., Larroque, S., Heine, L., Martial, C., Majerus, S., Laureys, S., & Di Perri, C. (2018). Clinical subcategorization of minimally conscious state according to resting functional connectivity. Human Brain Mapping, 39(11), 4519-4532. doi: 10.1002/hbm.243
2-year Impact Factor: 4.554|2018
Times cited: 4|2020-04-02
Indexed document: Yes
Quartile: Q1
Keywords: MCS minus and plus / Auditory network / Default mode network / Frontoparietal network / Functional connectivity / Language / Resting state fMRI / Structural imaging

DocumentBrain, behavior and cognitive interplay in disorders of consciousness: A multiple case study2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-16
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Brain, behavior and cognitive interplay in disorders of consciousness: A multiple case study
Publication year: 2018
URL:
https://www.frontiersin.org/articles/10.3389/fneur.2018.00665/full
Abstract/Results: ABSTRACT:
Patients with prolonged disorders of consciousness (DoC) after severe brain injury may present residual behavioral and cognitive functions. Yet the bedside assessment of these functions is compromised by patients' multiple impairments. Standardized behavioral scales such as the Coma Recovery Scale-Revised (CRS-R) have been developed to diagnose DoC, but there is also a need for neuropsychological measurement in these patients. The Cognitive Assessment by Visual Election (CAVE) was therefore recently created. In this study, we describe five patients in minimally conscious state (MCS) or emerging from the MCS (EMCS). Their cognitive profiles, derived from the CRS-R and CAVE, are presented alongside their neuroimaging results using structural magnetic resonance imaging (MRI) and fluorodeoxyglucose positron emission tomography (FDG-PET). Scores on the CAVE decreased along with the CRS-R total score, establishing a consistent behavioral/cognitive profile for each patient. Out of these five cases, the one with highest CRS-R and CAVE performance had the least extended cerebral hypometabolism. All patients showed structural and functional brain impairments that were consistent with their behavioral/cognitive profile as based on previous literature. For instance, the presence of visual and motor residual functions was respectively associated with a relative preservation of occipital and motor cortex/cerebellum metabolism. Moreover, residual language comprehension skills were found in the presence of preserved temporal and angular cortex metabolism. Some patients also presented structural impairment of hippocampus, suggesting the presence of memory impairments. Our results suggest that brain-behavior relationships might be observed even in severely brain-injured patients and they highlight the importance of developing new tools to assess residual cognition and language in MCS and EMCS patients. Indeed, a better characterization of their cognitive profile will be helpful in preparation of rehabilitation programs and daily routines.
Accessibility: Document exists in file
Language:
eng
Author:
Aubinet, C.
Secondary author(s):
Murphy, L., Ali Bahri, M., Larroque, S. K., Cassol, H., Annen, A., Carrière, M., Wannez, S., Thibaut, A., Laureys, S., Gosseries, O.
Document type:
Article
Reference:
Aubinet, C., Murphy, L., Ali Bahri, M., Larroque, S. K., Cassol, H., Annen, A., Carrière, M., Wannez, S., Thibaut, A., Laureys, S., & Gosseries, O. (2018). Brain, behavior and cognitive interplay in disorders of consciousness: A multiple case study. Frontiers in Neurology, 9: 665. doi: 10.3389/fneur.2018.00665
2-year Impact Factor: 2.635|2018
Times cited: 3|2020-04-02
Indexed document: Yes
Quartile: Q3
Keywords: (emergence from) minimally conscious state / Behavior / Cognitive functions / Neural correlates / Neuropsychological assessment / Positron emission tomography / Structural magnetic resonance imaging

Brain, behavior and cognitive interplay in disorders of consciousness: A multiple case study

Brain, behavior and cognitive interplay in disorders of consciousness: A multiple case study

DocumentMeditation-induced modulation of brain response to transcranial magnetic stimulation2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-17
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Meditation-induced modulation of brain response to transcranial magnetic stimulation
Publication year: 2018
URL:
https://www.brainstimjrnl.com/article/S1935-861X(18)30301-2/fulltext
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Bodart, O.
Secondary author(s):
Fecchio, M., Massimini, M., Wannez, S., Virgillito, A., Casarotto, S., Rosanova, M., Lutz, A., Ricard, M., Laureys, S., Gosseries, O.
Document type:
Article
Reference:
Bodart, O., Fecchio, M., Massimini, M., Wannez, S., Virgillito, A., Casarotto, S., Rosanova, M., Lutz, A., Ricard, M., Laureys, S., & Gosseries, O. (2018). Meditation-induced modulation of brain response to transcranial magnetic stimulation. Brain Stimulation, 11(6), 1397-1400. doi: 10.1016/j.brs.2018.08.018
2-year Impact Factor: 6.919|2018
Times cited: 2|2020-04-02
Indexed document: Yes
Quartile: Q1
Keywords: Meditation / Transcranial magnetic stimulation (TMS)

DocumentDiagnostic, pronostic et traitements des troubles de la conscience2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-18
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Diagnostic, pronostic et traitements des troubles de la conscience
Publication year: 2018
URL:
https://www.sciencedirect.com/science/article/pii/S1627483017300661
Abstract/Results: ABSTRACT:
Advances in medicine and intensive care have led to an increase in the number of patients surviving a severe brain injury. Although some patients recover quickly, others remain in a state of altered consciousness. These patients can progress from a coma to a vegetative state or unresponsive wakefulness syndrome (VS/UWS) and later to a minimally conscious state (MCS). In this review, we first describe the different behavioral and neuroimaging methods used in the diagnosis of patients in an altered state of consciousness. We then describe the factors that can influence the prognosis and recovery of these patients, as well as the treatment and therapeutic management that can be proposed in order to improve their state of consciousness. Finally, we conclude this review by highlighting ethical considerations and end-of-life issues.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
french
Author:
Cassol, H.
Secondary author(s):
Aubinet, C., Thibaut, A., Wannez, S., Martial, C., Martens, G., Laureys, S.
Document type:
Article
Reference:
Cassol, H., Aubinet, C., Thibaut, A., Wannez, S., Martial, C., Martens, G., & Laureys, S. (2018). Diagnosis, prognosis and treatment in disorders of consciousness [Diagnostic, pronostic et traitements des troubles de la conscience]. NPG Neurologie - Psychiatrie - Geriatrie, 18(103), 38-46.
Indexed document: Yes
Keywords: Consciousness / Brain injury / Diagnosis / Prognosis / Treatment / Altered states of consciousness / Coma / Vegetative state / Unresponsive wakefulness syndrome / Minimally conscious state / Locked-in syndrome / Neuroimaging / Positron emission tomography / Coma Recovery Scale-Revised / Magnetic resonance / Electroencephalography / Transcranial magnetic stimulation

DocumentMemories of near-death experiences: Are they self-defining? 2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: NDE
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories
Duration: 2016-03 - 2019-03
Researcher(s):
Steven Laureys, Charlotte Martial, Vanessa Charland-Verville, Héléna Cassol
Institution(s): Coma Science Group, University of Liège (Belgium)
Contents: Application
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Laureys, S.
Keywords:
Parapsychology and Psychophysiology / Near-death experience / Functional magnetic resonance imaging (fMRI)

Reference code: NDE-19
Location: Arquivo PCA - Pasta 1/Outros Apoios
Title:
Memories of near-death experiences: Are they self-defining?
Publication year: 2019
URL:
https://academic.oup.com/nc/article/2019/1/niz002/5368150
Abstract/Results: ABSTRACT:
Some people report memories of near-death experiences (NDEs) after facing situations of impending death and these memories appear to have significant consequences on their lives (here referred to as “real NDE experiencers”; real NDErs). We assessed to what extent NDE memories are considered self-defining: memories that help people to define clearly how they see themselves. We screened 71 participants using the Greyson NDE scale (48 real NDErs and 23 NDErs-like who had lived a similar experience in absence of a threat to their life). Participants described their two main self-defining memories (SDMs). For each SDM, they completed the Centrality of Event Scale (CES) to assess how central the event is to their identity. The two subgroups did not differ regarding the proportion of NDErs who recalled their NDE (30 real NDErs out of 48 and 11 NDErs-like out of 23). Real NDErs and NDErs-like who recalled their NDE (n?=?41) reported richer experiences as assessed by the Greyson NDE scale. Furthermore, these participants rated their NDE memory as more central to their identity as compared to other SDMs, and the richness of the NDE memory was positively associated to its centrality (CES scores). Overall, these findings suggest that the self-defining aspect of the experience might be related to its phenomenological content rather than its circumstances of occurrence. The self-defining status of NDE memories confirms that they constitute an important part of NDErs’ personal identity and highlights the importance for clinicians to facilitate their integration within the self.
Accessibility: Document exists in file
Language:
eng
Author:
Cassol, H.
Secondary author(s):
D’argembeau, A., Charland-Verville, V., Laureys, S., Martial, C.
Document type:
Article
Reference:
Cassol, H., D’argembeau, A., Charland-Verville, V., Laureys, S., & Martial, C. (2019). Memories of near-death experiences: Are they self-defining? Neuroscience of Consciousness, (1): niz002. doi: 10.1093/nc/niz002
Times cited: 4|2020-07-30
Indexed document: Yes
Keywords: Near-death experiences / Near-death experiences-like / Self-defining memories / Autobiographical memory / Centrality of Event Scale

Memories of near-death experiences: Are they self-defining?

Memories of near-death experiences: Are they self-defining?