Processing, please wait...
Database
search
in
Filter year from
to
Language
Country
  • Enter your search phrase in the search box.
  • General search:
    • The Boolean operator AND between the terms is assumed by default. If you enter the words European Union in the search box, the system returns all records in which both words occur, regardless of their order.
    • When entering a set of words in quotes, e.g "european union", all records containing the literal term "European Union" will be retrieved.
  • Search by access fields (e.g. author, title, etc.):
    • To direct your search, choose the field in which you want to search the word or expression.
    • Search in the field assumes by default the expression in quotes, e.g. European union will retrieve all records containing the literal term "European Union"
  • To perform more complex searches, additional words or expressions may be added.
  • If you want to refine the search results, you can always access the link "search" in the upper left corner of the page of search results.
  • The search engine is not case sensitive. For example, the word congress has the same meaning that Congress or CONGRESS.
  • To truncate your search expression, use the $ character
  • You can filter the results of your search by a date or date range, filling the appropriate boxes.
Base:
BIAL Foundation
Search:
cod:"PT/FB/BL-2000-054$"
Results
1
to
13
from
13
found.
View
Selection Description
Type Title Begin End
File054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2001-052003-03

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

DocumentFinal report - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2002

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.01
Location: Arquivo PCA - Pasta 3/2000
Title:
Final report - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Publication year: 2002
URL:
http://www.bial.com/imagem/Bolsa5400_19022014.pdf
Abstract/Results: RESULTS:
Behavioural interventions including biofeedback represent an alternative or adjunctive therapeutic axis in the management of drug refractory epilepsy. Our previous study suggested that the modulation of the peripheral state of arousal as indexed by the Galvanic Skin Response (GSR) had considerable influence on cortical excitability, indicating the possible use of biofeedback in controlling seizure activity. In the present study we investigated the effect of the GSR biofeedback training on seizure frequency in patients with treatment resistant epilepsy. Eighteen patients with drug refractory epilepsy were randomly assigned either to an active GSR biofeedback group (n = 10) or to a sham control biofeedback group (n = 8). Patients received a total of 12 sessions over four weeks, representing either real GSR biofeedback training, where subjects were trained to control their GSR by receiving feedback of their own GSR change on the computer screen, or sham training, where the feedback was unrelated to the subjects’ GSR.
Biofeedback training significantly reduced patients’ seizure frequency in the active biofeedback group (p = 0.005), but not the control group (p>0.10). This was manifest as a significant between group differences in seizure reduction (p = 0.016). Furthermore there was a correlation between degree of patients’ improvement in biofeedback performance and reduction of seizure frequency (rho = 0.736, p = 0.001), confirming that the effect of biofeedback treatment was related to physiological change. Our findings demonstrate that a behavioural intervention, GSR biofeedback training, may be associated with a significant reduction in seizure frequency in drug refractory epilepsy, highlighting the potential therapeutic value of this method.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Goldstein, L., Fenwick, P., Trimble, M. R.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Epilepsy / Galvanic skin response (GSR) / Intervention

Relatório final - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

Relatório final - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

DocumentClinical efficacy of galvanic skin response biofeedback training in reducing seizures in adult epilepsy: a preliminary randomized controlled study2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.02
Location: Arquivo PCA - Pasta 3/2000
Title:
Clinical efficacy of galvanic skin response biofeedback training in reducing seizures in adult epilepsy: a preliminary randomized controlled study
Publication year: 2004
URL:
http://www.sciencedirect.com/science/article/pii/S1525505003003950
Contents: http://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=160&SID=V1leIhH4ysTdNpr3OrX&page=1&doc=1
Abstract/Results: ABSTRACT:
We investigated the effect of galvanic skin response (GSR) biofeedback training on seizure frequency in patients with treatment-resistant epilepsy. Eighteen patients with drug-refractory epilepsy were randomly assigned either to an active GSR biofeedback group (n=10) or to a sham control biofeedback group (n=8). Biofeedback training significantly reduced seizure frequency in the active biofeedback group (P=0.017), but not the control group (P>0.10). This was manifest as a significant between-group difference in seizure reduction (P=0.01). Furthermore, there was a correlation between degree of improvement in biofeedback performance and reduction of seizure frequency (?=0.736, P=0.001), confirming that the effect of biofeedback treatment was related to physiological change. Our findings highlight the potential therapeutic value of GSR biofeedback in reducing seizure frequency in patients with drug-resistant epilepsy.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Goldstein, L., Fenwick, P., Trimble, M. R.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Goldstein, L., Fenwick, P., & Trimble, M. R. (2004). Clinical efficacy of galvanic skin response biofeedback training in reducing seizures in adult epilepsy: a preliminary randomized controlled study. Epilepsy & Behaviour, 5(2), 216-223. https://doi.org/10.1016/j.yebeh.2003.12.003
2-year Impact Factor: 1.630|2004
Times cited: 79|2025-02-04
Indexed document: Yes
Quartile: Q2
Keywords: Galvanic skin response (GSR) / Biofeedback / Randomized controlled study / Drug refractory epilepsy / Seizure reduction

Clinical efficacy of biofeedback treatment on reducing seizures in adult epilepsy: a preliminary randomized controlled study

Clinical efficacy of biofeedback treatment on reducing seizures in adult epilepsy: a preliminary randomized controlled study

DocumentBrain activity relating to the Contingent Negative Variation (CNV): fMRI investigation2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.03
Location: Arquivo PCA - Pasta 3/2000
Title:
Brain activity relating to the Contingent Negative Variation (CNV): fMRI investigation
Publication year: 2004
URL:
http://www.ncbi.nlm.nih.gov/pubmed/15050551
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=13&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
The contingent negative variation (CNV) is a long-latency electroencephalography (EEG) surface negative potential with cognitive and motor components, observed during response anticipation. CNV is an index of cortical arousal during orienting and attention, yet its functional neuroanatomical basis is poorly understood. We used functional magnetic resonance imaging (fMRI) with simultaneous EEG and recording of galvanic skin response (GSR) to investigate CNV-related central neural activity and its relationship to peripheral autonomic arousal. In a group analysis, blood oxygenation level dependent (BOLD) activity during the period of CNV generation was enhanced in thalamus, somatomotor cortex, bilateral midcingulate, supplementary motor, and insular cortices. Enhancement of CNV-related activity in anterior and midcingulate, SMA, and insular cortices was associated with decreases in peripheral sympathetic arousal. In a subset of subjects in whom we acquired simultaneous EEG and fMRI data, we observed activity in bilateral thalamus, anterior cingulate, and supplementary motor cortex that was modulated by trial-by-trial amplitude of CNV. These findings provide a likely functional neuroanatomical substrate for the CNV and demonstrate modulation of components of this neural circuitry by peripheral autonomic arousal. Moreover, these data suggest a mechanistic model whereby thalamocortical interactions regulate CNV amplitude.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D. , Featherstone, E., Fenwick, P., Trimble, M. R., Dolan, R. J.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Critchley, H. D., Featherstone, E., Fenwick, P., Trimble, M. R.,& Dolan, R. J. (2004). Brain activity relating to the Contingent Negative Variation (CNV): fMRI investigation. NeuroImage, 21(4), 1232-1241. https://doi.org/10.1016/j.neuroimage.2003.10.036
2-year Impact Factor: 4.869|2004
Times cited: 283|2025-02-04
Indexed document: Yes
Quartile: Q1
Keywords: Contingent negative variation (CNV) / Electroencephalography / Blood oxygenation level dependent

Brain activity relating to the Contingent Negative Variation (CNV): fMRI investigation

Brain activity relating to the Contingent Negative Variation (CNV): fMRI investigation

DocumentActivity inventromedial prefrontal cortex covaries with sympathetic skin conductance level (SCL): a physiological account of a "default mode" of brain function2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.04
Location: Arquivo PCA - Pasta 3/2000
Title:
Activity inventromedial prefrontal cortex covaries with sympathetic skin conductance level (SCL): a physiological account of a "default mode" of brain function
Publication year: 2004
URL:
http://www.sciencedirect.com/science/article/pii/S1053811904000540
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=15&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
We examined neural activity related to modulation of skin conductance level (SCL), an index of sympathetic tone, using functional magnetic resonance imaging (fMRI) while subjects performed biofeedback arousal and relaxation tasks. Neural activity within the ventromedial prefrontal cortex (VMPFC) and the orbitofrontal cortex (OFC) covaried with skin conductance level (SCL), irrespective of task. Activity within striate and extrastriate cortices, anterior cingulate and insular cortices, thalamus, hypothalamus and lateral regions of prefrontal cortex reflected the rate of change in electrodermal activity, highlighting areas supporting transient skin conductance responses (SCRs). Successful performance of either biofeedback task (where SCL changed in the intended direction) was associated with enhanced activity in mid-OFC. The findings point to a dissociation between neural systems controlling basal sympathetic tone (SCL) and transient skin conductance responses (SCRs). The level of activity in VMPFC has been related to a default mode of brain function and our findings provide a physiological account of this state, indicating that activity within VMPFC and OFC reflects a dynamic between exteroceptive and interoceptive deployment of attention.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D., Featherstone, E., Trimble, M. R., Dolan, R. J.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Critchley, H. D., Featherstone, E., Trimble, M. R., & Dolan, R. J. (2004). Activity in ventromedial prefrontal cortex covaries with sympathetic skin conductance level: a physiological account of a "default mode" of brain function. NeuroImage, 22(1), 243-251. https://doi.org/10.1016/j.neuroimage.2004.01.019
2-year Impact Factor: 4.869|2004
Times cited: 330|2025-02-04
Indexed document: Yes
Quartile: Q1
Keywords: Skin conductance / Functional magnetic resonance imaging (fMRI) / Biofeedback

DocumentInfluence of sympathetic autonomic arousal on cortical arousal: implications for a therapeutic behavioural intervention in epilepsy2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.05
Location: Arquivo PCA - Pasta 3/2000
Title:
Influence of sympathetic autonomic arousal on cortical arousal: implications for a therapeutic behavioural intervention in epilepsy
Publication year: 2004
URL:
http://www.google.pt/url?sa=t&rct=j&q=&esrc=s&frm=1&source=web&cd=1&cad=rja&ved=0CDAQFjAA&url=http%3A%2F%2Fciteseerx.ist.psu.edu%2Fviewdoc%2Fdownload%3Fdoi%3D10.1.1.124.795%26rep%3Drep1%26type%3Dpdf&ei=tEjNUcjKIfSR7Aab1oBg&usg=AFQjCNHjj37kSx3p2CPlzuuH7h6K96Xs-w&sig2=PbDr5s-sOh4IwUUKET5uUw&bvm=bv.48572450,d.ZWU
Abstract/Results: ABSTRACT:
Negative amplitude shifts of cortical potential are related to seizure activity in epilepsy. Regulation of the cortical potential with biofeedback has been successfully used to reduce the frequency of some patients’ seizures. Although such behavioural treatments are increasingly popular as an alternative to pharmacotherapy, there has been no investigation of the mechanisms that might bridge the behavioural index of peripheral autonomic activity and the central regulation of arousal. Galvanic Skin Response (GSR) is a sensitive measurement of autonomic arousal and physiological state which reflects one’s behaviour. Thus we investigated the effect of peripheral autonomic modulation on cortical arousal with the future intention of using GSR biofeedback as a therapeutic treatment for epilepsy. The cortical negative potential was induced using the paradigm called Contingent Negative Variation (CNV) and measured in different physiological states. A high skin resistance state (reflecting a state of relaxation) and a low skin resistance state (reflecting a state of arousal), were engendered by two opposing procedures of GSR biofeedback. The CNV negative potential, acting as an index of cortical excitation, was significantly greater in amplitude at high levels of skin resistance (relaxed state) than at low levels of skin resistance (aroused state). Our results suggest an inverse relationship between a peripheral measure of autonomic arousal and an index of cortical arousal, the CNV. Moreover, we demonstrate modulation of this arousal-related potential by a behavioural intervention, indicating a potential therapeutic use of arousal biofeedback using GSR in the management of treatment-resistant epilepsy.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Goldstein, L., Critchley, H. D., Fenwick, P.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Goldstein, L., Critchley, H. D., & Fenwick, P. (2004). Influence of sympathetic autonomic arousal on cortical arousal: implications for a therapeutic behavioural intervention in epilepsy. Epilepsy Research, 58(2-3), 185-193. https://doi.org/10.1016/j.eplepsyres.2004.02.004
2-year Impact Factor: 2.897|2004
Times cited: 41|2025-02-04
Indexed document: Yes
Quartile: Q1
Keywords: Contingent negative variation (CNV) / Galvanic Skin Response (GSR) / Biofeedback

Influence of sympathetic autonomic arousal on contingent negative variation: implications for a therapeutic behavioural intervention in epilepsy

Influence of sympathetic autonomic arousal on contingent negative variation: implications for a therapeutic behavioural intervention in epilepsy

DocumentChanges in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.06
Location: Arquivo PCA - Pasta 3/2000
Title:
Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy
Publication year: 2009
URL:
http://www.psychosomaticmedicine.org/content/71/1/84.full.pdf
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=19&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
OBJECTIVES:
To examine the immediate and sustained effects of volitional sympathetic modulation, using galvanic skin response (GSR) biofeedback training on cortical excitability in patients with drug-resistant epilepsy.
METHODS:
Ten patients undertook 12 sessions of GSR biofeedback training over 1 month, during which they were trained to increase sympathetic arousal, using GSR biofeedback. Contingent negative variation (CNV) (a slow cortical potential reflecting cortical arousal and excitability) and the related post imperative negative variation (PINV) were quantified before and after biofeedback treatment.
RESULTS:
A significant reduction in CNV amplitude was observed in both the short-term (within the first session, after 10 minutes of GSR biofeedback) and long-term (sustained after 12 training sessions). Specifically, the change in baseline CNV amplitude after the 12 training sessions correlated with a percentage reduction in seizure frequency. Furthermore, changes in baseline amplitude of the PINV also correlated with seizure reduction.
CONCLUSIONS:
Our findings demonstrate that behavioral enhancement of peripheral sympathetic tone (GSR) is associated with modulation of indices of cortical excitability. Moreover, GSR biofeedback training over repeated sessions was associated with a chronic baseline reduction in slow cortical potentials and concurrent therapeutic improvement.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D., Rothwell, J. C., Duncan, J. S., Trimble, M. R.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y., Critchley, H. D., Rothwell, J. C., Duncan, J. S., & Trimble, M. R. (2009). Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy. Psychosomatic Medicine, 71(1), 84-92. https://doi.org/10.1097/PSY.0b013e31818f667c
2-year Impact Factor: 4.236|2009
Times cited: 26|2025-02-07
Indexed document: Yes
Quartile: Q1
Keywords: Biofeedback / Galvanic skin response (GSR) / Contingent negative variation (CNV) / Slow cortical potentials / Post imperative negative / Epilepsy

Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy

Changes in cortical potential associated with modulation of peripheral sympathetic activity in patients with epilepsy

DocumentBehavioral treatment for epilepsy2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.07
Location: Arquivo PCA - Pasta 3/2000
Title:
Behavioral treatment for epilepsy
Publication year: 2007
Accessibility:
Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Document type:
Book chapter
Number of reproductions:
1
Reference:
Nagai, Y. (2007). Behavioral treatment for epilepsy. In K. J. Hollaway (Ed.), New research on epilepsy and behavior (pp. 279-294). New York, NY: Nova Publisher.
Indexed document: No
Keywords: Psychophysiology / Epilepsy

DocumentNovel application of electrodermal biofeedback to neurological disorder: therapeutic and neural mechanisms2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.08
Location: Arquivo PCA - Pasta 3/2000
Title:
Novel application of electrodermal biofeedback to neurological disorder: therapeutic and neural mechanisms
Publication year: 2007
Accessibility:
Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Critchley, H. D.
Document type:
Book chapter
Number of reproductions:
1
Reference:
Nagai, Y., & Critchley, H. D. (2007). Novel therapeutic application of Galvanic Skin Response (GSR) biofeedback to a neurological disorder: Mechanisms underlying biofeedback in epilepsy management. In H. L. Puckhaber(Ed.), New research in biofeedback (pp. 1-31). New York, NY: Nova Publisher.
Indexed document: No
Keywords: Psychophysiology / Neurological disorder / Biofeedback

DocumentEffect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2002

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.09
Location: Arquivo PCA - Pasta 3/2000
Title:
Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Publication year: 2002
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/4%C2%BA_simposio.a110.html
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Fenwick, P., Goldstein, L., Lumsden, J., Trimble, M. R.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Nagai, Y., Fenwick, P., Goldstein, L., Lumsden, J., & Trimble, M. R. (2002). Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 4th Symposium of Fundação Bial (p. 448). Porto: Fundação Bial.
Indexed document: No
Keywords: Psychophysiology / Epilepsy / Galvanic skin response (GSR)

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

DocumentEffect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy2004

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.10
Location: Arquivo PCA - Pasta 3/2000
Title:
Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Publication year: 2004
URL:
http://www.bial.com/pt/fundacao_bial.11/simposios.19/edicoes_anteriores.75/5%C2%BA_simposio.a111.html
Abstract/Results: ABSTRACT:
Behavioural interventions including biofeedback represent an alternative or adjunctive therapeutic axis in the management of drug refractory epilepsy. Our previous study suggested that the modulation of the peripheral state of arousal as indexed by the Galvanic Skin Response (GSR) had considerable influence on cortical excitability, indicating the possible use of biofeedback in controlling seizure activity.
We investigated the effect of the GSR biofeedback training on seizure frequency in patients with treatment resistant epilepsy. Eighteen patients with drug refractory epilepsy were randomly assigned either to an active GSR biofeedback group (n = 10) or to a sham control biofeedback group (n = 8). Patients received a total of 12 sessions over four weeks, representing either real GSR biofeedback training, where subjects were trained to decrease skin resistance using biofeedback, or sham training, where the feedback was unrelated to the subjects’ GSR. Biofeedback training significantly reduced patients’ seizure frequency in the active biofeedback group (p = 0.017), but not the control group (p>0.10). This was manifest as a significant between group difference in seizure reduction (p = 0.01). Our findings demonstrate that a behavioural intervention, GSR biofeedback training, may substantially reduce seizure frequency in drug refractory epilepsy, highlighting the potential therapeutic value of this method.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Nagai, Y., Trimble, M. R., Fenwick, P., Goldstein, L., & Lumsden, J. (2004). Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 5th Symposium of Fundação Bial (pp. 306-307). Porto: Fundação Bial.
Indexed document: No
Keywords: Psychophysiology / Epilepsy / Galvanic skin response (GSR)

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy

DocumentLong-term effects of electrodermal biofeedback training on seizure control in patients with drug-resistant epilepsy: Two case reports2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.11
Location: Arquivo PCA - Pasta 3/2000
Title:
Long-term effects of electrodermal biofeedback training on seizure control in patients with drug-resistant epilepsy: Two case reports
Publication year: 2014
URL:
http://www.epires-journal.com/article/S0920-1211(13)00258-1/abstract
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=25&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
We report data from two patients, followed over 3 years after electrodermal biofeedback treatment. Patients were trained three times each week for four weeks to increase their sympathetic arousal using electrodermal biofeedback. This treatment was directed at enabling the patients to change their psychophysiological state as a countermeasure to prevent seizures. Both patients voluntarily kept a record of seizure frequency over the year preceding the treatment and continued to record their seizures for up to 3 years after the termination of biofeedback treatment. Both patients showed a marked reduction in seizure frequency (54.9% and 59.8%) during the month of biofeedback treatment. This improvement was maintained over the subsequent years. We highlight the therapeutic potential of biofeedback interventions that enable patients to volitionally control their state of physiological arousal in the management of drug-resistant epilepsy.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Secondary author(s):
Trimble, M. R.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Nagai, Y., & Trimble, M. R. (2014). Long-term effects of electrodermal biofeedback training on seizure control in patients with drug-resistant epilepsy: Two case reports. Epilepsy Research, 108(1), 149-152. https://doi.org/10.1016/j.eplepsyres.2013.10.004
2-year Impact Factor: 2.015|2014
Times cited: 16|2025-02-10
Indexed document: Yes
Quartile: Q3
Keywords: Biofeedback / Electrodermal activity (EDA) / Drug resistant epilepsy

DocumentBiofeedback and epilepsy2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2000
Location: Arquivo PCA - Pastas 1 a 13/2000
Title:
2000 Grants
Start date: 2001-01 - 2014-02
Dimension/support:
13 caixas de arquivo

Reference code: PT/FB/BL-2000-054
Location: Arquivo PCA - Pasta 3/2000
Title:
054 - Effect of Galvanic Skin Response (GSR) biofeedback on seizure frequency in patients with poorly controlled epilepsy
Duration: 2001-05 - 2003-03
Researcher(s):
Yoko Nagai, Michael Trimble, Peter Fenwick, Laura Goldstein, John Lumsden
Institution(s): Institute of Neurology, University College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Article
Author: Nagai, Y.
Secondary author(s):
Trimble, M. R., Fenwick, P., Goldstein, L., Lumsden, J.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Diseases/Injuries / Epilepsy / Intervention

Reference code: PT/FB/BL-2000-054.12
Location: Arquivo PCA - Pasta 3/2000
Title:
Biofeedback and epilepsy
Publication year: 2011
URL:
http://link.springer.com/article/10.1007%2Fs11910-011-0201-3
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=27&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
Biofeedback is a noninvasive behavioral treatment that enables a patient to gain volitional control over a physiological process. As a treatment for epilepsy, biofeedback interventions were explored from as early as the 1970s, concentrating on sensory motor rhythm (SMR) as a neurophysiologic parameter. Whereas SMR biofeedback aims to modulate frequency components of the electroencephalography (EEG), slow cortical potential (SCP) biofeedback (which was introduced in the 1990s) focuses on the regulation of the amplitude of cortical potential changes (DC shift). In its application to epilepsy, biofeedback using galvanic skin response (GSR), an electrodermal measure of sympathetic activity, is a relatively new cost-effective methodology. The present article first reviews biofeedback using SMR and SCP, for which efficacy and neural mechanisms are relatively well characterized. Then recent data regarding promising applications of GSR biofeedback will be introduced and discussed in detail.
Accessibility: Document does not exist in file
Language:
eng
Author:
Nagai, Y.
Document type:
Article
Number of reproductions:
1
Reference:
Nagai, Y. (2011). Biofeedback and epilepsy. Current Neurology and Neuroscience Reports, 11(4), 443-450. https://doi.org/10.1007/s11910-011-0201-3
2-year Impact Factor: 3.455|2011
Times cited: 21|2025-02-10
Indexed document: Yes
Quartile: Q1
Keywords: Biofeedback / Volitional control / Sensory motor rhythm (SMR) / Slow cortical potentials (SCPs) / Galvanic skin response (GSR)