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File090 - Brain function, creativity, paranormal ideation and risk for psychosis2003-032005-04

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-090
Location: Arquivo PCA - Pasta 5/2002
Title:
090 - Brain function, creativity, paranormal ideation and risk for psychosis
Duration: 2003-03 - 2005-04
Researcher(s):
Alexander Sumich, Michael Brammer, Dominic Ffytch
Institution(s): Brain Image Analysis Unit, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Diskette (Reseacrch Bursary 02-03, Alex Sumich: Brain function, creativity, paranormal ideation and risk for psychosis - BIAL)
Language: eng
Author:
Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders
DocumentFinal report - Brain function, creativity, paranormal ideation and risk for psychosis 2005

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-090
Location: Arquivo PCA - Pasta 5/2002
Title:
090 - Brain function, creativity, paranormal ideation and risk for psychosis
Duration: 2003-03 - 2005-04
Researcher(s):
Alexander Sumich, Michael Brammer, Dominic Ffytch
Institution(s): Brain Image Analysis Unit, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Diskette (Reseacrch Bursary 02-03, Alex Sumich: Brain function, creativity, paranormal ideation and risk for psychosis - BIAL)
Language: eng
Author:
Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2002-090.01
Location: Arquivo PCA - Pasta 5/2002
Title:
Final report - Brain function, creativity, paranormal ideation and risk for psychosis
Publication year: 2005
URL:
http://www.bial.com/imagem/Bolsa9002_19022014.pdf
Abstract/Results: RESULTS:
Compared to healthy controls, men with recent onset psychosis (ROP) have reduced anterior N100 amplitude, enhanced left temporal and frontal N200 amplitude and reduced left temporal and posterior P300 amplitude. Insight/judgement (IJ), rapport and depression are negatively associated with N200 amplitude implicating executive mechanisms. Reduced N200 amplitude in higher-depression ROP contrasts enhanced N200 in major depression, suggesting aetiological differences for depression between diagnoses. However, lower right anterior N200 in high-depression ROP is consistent with subclinical depression in healthy men. The relationship between right anterior N200 and depression in ROP did not persist after controlling for IJ. Thus, a contribution of intact IJ to depression in ROP is supported.
Psychomotor poverty is associated with reduced N100 amplitude. Lower left P300 is associated with total psychopathology. Various mechanisms found abnormal in ROP are also implicated in paranormal ideation (PI) including enhanced anterior N200 and reduced left- and anterior- P300 amplitude. However, in contrast to ROP, high-PI is associated with enhanced N100 amplitude which may represent a compensatory mechanism protecting against the onset of psychosis. On the other hand, paranoia/suspiciousness (PS) is associated with reduced anterior N100 and enhanced N200 in healthy men, but not women, supporting an association between PS and mechanisms implicated in negative symptoms. Results suggest the existence of a continuum of psychosis which is further supported by observed sex differences in the ERP-personality relationship reflective of those previously reported in schizophrenia. PI and PS may represent distinct risk factors for psychosis.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Notes:
The final report consists of 4 posters and 5 articles (see attachment)
Author: Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Brain structure and function / Schizophrenia / Depression

Novo ficheiro

Novo ficheiro
DocumentBrain function, creativity, paranormal ideation and risk for psychosis2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-090
Location: Arquivo PCA - Pasta 5/2002
Title:
090 - Brain function, creativity, paranormal ideation and risk for psychosis
Duration: 2003-03 - 2005-04
Researcher(s):
Alexander Sumich, Michael Brammer, Dominic Ffytch
Institution(s): Brain Image Analysis Unit, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Diskette (Reseacrch Bursary 02-03, Alex Sumich: Brain function, creativity, paranormal ideation and risk for psychosis - BIAL)
Language: eng
Author:
Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2002-090.02
Location: Arquivo PCA - Pasta 5/2002
Title:
Brain function, creativity, paranormal ideation and risk for psychosis
Publication year: 2006
URL:
http://www.bial.com/imagem/1178809516livroactas.pdf
Accessibility: Document does not exist in file
Language:
eng
Author:
Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Sumich, A., Brammer, M., & Ffytch, D. (2006). Brain function, creativity, paranormal ideation and risk for psychosis. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 6th Symposium of Fundação Bial (p. 254). Porto: Fundação Bial.
Indexed document: No
Keywords: Psychophysiology / Psychosis / Paranormal ideation / Schizophrenia

Novo ficheiro

Novo ficheiro
DocumentEvent-related potential correlates of paranormal ideation and unusual experiences2008

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-090
Location: Arquivo PCA - Pasta 5/2002
Title:
090 - Brain function, creativity, paranormal ideation and risk for psychosis
Duration: 2003-03 - 2005-04
Researcher(s):
Alexander Sumich, Michael Brammer, Dominic Ffytch
Institution(s): Brain Image Analysis Unit, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Diskette (Reseacrch Bursary 02-03, Alex Sumich: Brain function, creativity, paranormal ideation and risk for psychosis - BIAL)
Language: eng
Author:
Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2002-090.03
Location: Arquivo PCA - Pasta 5/2002
Title:
Event-related potential correlates of paranormal ideation and unusual experiences
Publication year: 2008
URL:
http://www.ncbi.nlm.nih.gov/pubmed/18625497
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=288&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
Separate dimensions of schizotypy have been differentially associated with electrophysiological measures of brain function, and further shown to be modified by sex/gender. We investigated event-related potential (ERP) correlates of two subdimensions of positive schizotypy, paranormal ideation (PI) and unusual experiences (UEs). Seventy-two individuals with no psychiatric diagnosis (men=36) completed self-report measures of UE and PI and performed an auditory oddball task. Average scores for N100, N200 and P300 amplitudes were calculated for left and right anterior, central and posterior electrode sites. Multiple linear regression was used to examine the relationships between the measures of schizotypy and ERPs across the entire sample, as well as separately according to sex. PI was inversely associated with P300 amplitude at left-central sites across the entire sample, and at right-anterior electrodes in women only. Right-anterior P300 and right-posterior N100 amplitudes were negatively associated with UE in women only. Across the entire sample, UE was negatively associated with left-central N100 amplitude, and positively associated with left-anterior N200 amplitude. These results provide support from electrophysiological measures for the fractionation of the positive dimension of schizotypy into subdimensions of PI and UE, and lend indirect support to dimensional or quasidimensional conceptions of psychosis. More specifically, they suggest that PI may be associated with alteration in contextual updating processes, and that UE may reflect altered sensory/early-attention (N100) mechanisms. The sex differences observed are consistent with those previously observed in individuals with schizophrenia.
Accessibility: Document does not exist in file
Language:
eng
Author:
Sumich, A.
Secondary author(s):
Kumari, V., Gordon, E., Tunstall, N., Brammer, M.
Document type:
Article
Number of reproductions:
1
Reference:
Sumich, A., Kumari, V., Gorden, E., Tunstall, N., & Brammer, M. (2008). Event-related potential correlates of paranormal ideation and unusual experiences. Cortex, 44(10), 1342-1352. doi: 10.1016/j.cortex.2007.10.012
2-year Impact Factor: 2.749|2008
Times cited: 26|2022-10-24
Indexed document: Yes
Quartile: Q2
Keywords: Schizotypy / N100 / N200 / P300 / Auditory oddball / Sex
DocumentEvent-related potential correlates of depression, insight and negative symptoms in males with recent-onset psychosis2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-090
Location: Arquivo PCA - Pasta 5/2002
Title:
090 - Brain function, creativity, paranormal ideation and risk for psychosis
Duration: 2003-03 - 2005-04
Researcher(s):
Alexander Sumich, Michael Brammer, Dominic Ffytch
Institution(s): Brain Image Analysis Unit, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Diskette (Reseacrch Bursary 02-03, Alex Sumich: Brain function, creativity, paranormal ideation and risk for psychosis - BIAL)
Language: eng
Author:
Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2002-090.04
Location: Arquivo PCA - Pasta 5/2002
Title:
Event-related potential correlates of depression, insight and negative symptoms in males with recent-onset psychosis
Publication year: 2006
URL:
http://www.ncbi.nlm.nih.gov/pubmed/16807100
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=290&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
OBJECTIVE - The neurobiology of clinical characteristics -in particular depression, insight and negative symptoms- in recent-onset psychosis (ROP) was studied using event-related potentials (ERPs).
METHODS - Twenty right-handed ROP men and 20 controls completed an auditory-oddball task. ROP men had minimum exposure to antipsychotic medication. N100, N200 and P300 were studied to ascertain the effects of (a) diagnosis (patients versus controls), and (b) clinical characteristics.
RESULTS - ROP men had significantly lower anterior N100, enhanced N200 at T3, and lower P300 at Pz than controls. Lower right-anterior N100 and enhanced right-anterior N200 amplitude explained 47.7% of negative symptoms. Left-central N100 amplitude explained 30.28% of negative symptoms. Lower left-posterior and higher right-posterior P300 amplitude explained 65.99% of total symptoms. Lower left-central N100, enhanced left-central N200 and depression explained 78.8% of impairments in insight and judgement. Impaired insight/judgement correlated positively with right-anterior N200 and was identified as the most significant co-efficient for depression.
CONCLUSIONS - Disturbed selective-attention and executive function indexed by N100 and N200, respectively, are associated with poor insight and negative symptoms. A complex interaction exists between insight and depression.
SIGNIFICANCE - The current results demonstrate a biological basis of insight and depression and a complex interaction between the two, perhaps mediated by executive function, in early psychosis.
Accessibility: Document does not exist in file
Language:
eng
Author:
Sumich, A.
Secondary author(s):
Harris, A., Flynn, G., Whitford, T., Tunstall, N., Kumari, V., Brammer, M., Gordon, E., Williams, L.
Document type:
Article
Number of reproductions:
1
Reference:
Sumich, A., Harris, A., Flynn, G., Whitford, T., Tunstall, N., Kumari, V., . . . Williams, L. M. (2006). Event-related potential correlates of depression, insight and negative symptoms in males with recent-onset psychosis. Clinical Neurophysiology, 117(8), 1715-1727. doi: 10.1016/j.clinph.2006.04.017
2-year Impact Factor: 2.718|2006
Times cited: 29|2022-10-24
Indexed document: Yes
Quartile: Q2
Keywords: Event-related potential (ERP) / Depression / Insight / Recent-onset psychosis / Negative symptoms
DocumentAbnormal asymmetry of N200 and P300 event-related potentials in subclinical depression2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-090
Location: Arquivo PCA - Pasta 5/2002
Title:
090 - Brain function, creativity, paranormal ideation and risk for psychosis
Duration: 2003-03 - 2005-04
Researcher(s):
Alexander Sumich, Michael Brammer, Dominic Ffytch
Institution(s): Brain Image Analysis Unit, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Diskette (Reseacrch Bursary 02-03, Alex Sumich: Brain function, creativity, paranormal ideation and risk for psychosis - BIAL)
Language: eng
Author:
Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2002-090.05
Location: Arquivo PCA - Pasta 5/2002
Title:
Abnormal asymmetry of N200 and P300 event-related potentials in subclinical depression
Publication year: 2006
URL:
http://www.jad-journal.com/article/S0165-0327(06)00007-3/abstract
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=292&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
Sex differences for depression in prevalence and symptom profile may in part be due to differences between men and women in brain dysfunction associated with the disorder. Changes in event-related potential (ERP) measures similar to those seen in clinical populations are reported in subclinical or premorbid forms of depression. The current study investigates sex differences in ERPs associated with subclinical depression. One-hundred-and-forty healthy, right-handed adults (aged 20–60 years; screened to exclude clinical depression and psychosis) completed an auditory oddball task and the Depression Anxiety and Stress Scale (DASS). Seventy (n=35 men) subclinically depressed (SD) (i.e. scoring >2 for depression on DASS) participants were matched for age and education with 70 (n=35 men) participants showing no signs of depression (ND). Repeated measures multivariate analysis of variance was used to test for differences in N200 and P300 amplitude between SD and ND groups. ND, but not SD groups had asymmetry (R>L) of central N200 amplitude. Similar asymmetry was seen in ND, but not SD men at posterior sites. SD groups demonstrated left>right posterior P300 amplitude asymmetry due to P300 enhancement at left temporoparietal sites. Results support involvement of various cognitive mechanisms measured by P300 and N200 in subclinical depressive symptoms some of which may rely on sex.
Accessibility: Document does not exist in file
Language:
eng
Notes:
Event-related potentials, N200, P300, Asymmetry, Depression, Subclinical
Author: Sumich, A.
Secondary author(s):
Kumari, V., Heasman, B., Gordon, E., Brammer, M.
Document type:
Article
Number of reproductions:
1
Reference:
Sumich, A., Kumari, V., Heasman, B., Gordon, E., & Brammer, M. (2006). Abnormal asymmetry of N200 and P300 event-related potentials in subclinical depression. Journal of Affective Disorders, 92(2-3), 171-183. doi: 10.1016/j.jad.2006.01.006
2-year Impact Factor: 3.138|2006
Times cited: 29|2022-10-24
Indexed document: Yes
Quartile: Q1
Keywords: Event-related potential (ERP) / N200 / P300 / Asymmetry / Depression / Subclinical
DocumentNeurophysiological correlates of excitement in schizophrenia2013

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-090
Location: Arquivo PCA - Pasta 5/2002
Title:
090 - Brain function, creativity, paranormal ideation and risk for psychosis
Duration: 2003-03 - 2005-04
Researcher(s):
Alexander Sumich, Michael Brammer, Dominic Ffytch
Institution(s): Brain Image Analysis Unit, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Diskette (Reseacrch Bursary 02-03, Alex Sumich: Brain function, creativity, paranormal ideation and risk for psychosis - BIAL)
Language: eng
Author:
Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2002-090.06
Location: Arquivo PCA - Pasta 5/2002
Title:
Neurophysiological correlates of excitement in schizophrenia
Publication year: 2013
URL:
http://www.sciencedirect.com/science/article/pii/S0278584613001309
Abstract/Results: ABSTRACT:
Objective: The excitement cluster (excitement, hostility, uncooperativeness and impulsivity) may contribute to the risk of violent behaviour, treatment non-adherence, likelihood of discharge and substance use in psychosis. Evidence suggests involvement of frontal executive mechanisms that may show sex differences in their association with symptom severity. The current study tests the association between excitement and the frontal N200 and P300 components of the auditory event-related potential in schizophrenia as a function of sex.
Method: Fourteen men and 14 women with schizophrenia (mean illness duration = 20 years) completed a novelty oddball and clinical interview.
Results: Men showed higher midline N200 and lower novelty P300 amplitude than women. They had more pronounced
differences between midline and lateral N200 amplitude, and did not show the same Novel N Target effect for right frontal P300 as did women. Right frontal N200 amplitude to target stimuli was positively associated with excitement in women and inversely associated with excitement in men. Novelty P300 amplitude was inversely associated with excitement, particularly in women and over the right hemisphere.
Conclusion: Results suggest that mechanisms underpinning frontal N200 and P300 subcomponents are differentially involved in excitement depending on sex. Understanding these individual differences may have implications
for developing personalised treatment.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Sumich, A.
Secondary author(s):
Castro, A., Anilkumar, A., Zachariach, E., Kumari, V.
Document type:
Article
Number of reproductions:
1
Percentiles:
7|2022-03-19
Reference:
Sumich, A., Castro, A., Anilkumar, A., Zachariach, E., & Kumari, V. (2013). Neurophysiological correlates of excitement in schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 46, 132–138. doi: 10.1016/j.pnpbp.2013.06.018
2-year Impact Factor: 4.025|2013
Times cited: 11|2022-10-24
Indexed document: Yes
Quartile: Q1
Keywords: Event-related potentials / Excitement / Frontal / N200 / Schizophrenia / Sex differences
DocumentNeurophysiological correlates of excitement in men with recent-onset psychosis2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-090
Location: Arquivo PCA - Pasta 5/2002
Title:
090 - Brain function, creativity, paranormal ideation and risk for psychosis
Duration: 2003-03 - 2005-04
Researcher(s):
Alexander Sumich, Michael Brammer, Dominic Ffytch
Institution(s): Brain Image Analysis Unit, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Diskette (Reseacrch Bursary 02-03, Alex Sumich: Brain function, creativity, paranormal ideation and risk for psychosis - BIAL)
Language: eng
Author:
Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders

Reference code: PT/FB/BL-2002-090.07
Location: Arquivo PCA - Pasta 5/2002
Title:
Neurophysiological correlates of excitement in men with recent-onset psychosis
Publication year: 2018
URL:
http://www.psychiatria-danubina.com/UserDocsImages/pdf/dnb_vol30_no1/dnb_vol30_no1_64.pdf
Abstract/Results: ABSTRACT:
OBJECTIVE:
Right frontal function, as indicated by the N200 component of the event-related potential during target detection, has previously been associated with excitement (excitement, impulsivity, hostility, uncooperativeness) in men with a long-term diagnosis of schizophrenia. The current study investigated excitement in relation to N200 in men who had recently experienced their first episode of psychosis.
SUBJECTS AND METHODS:
Twenty men who had recently suffered their first psychotic episode underwent a clinical interview and auditory oddball task.
RESULTS:
Multiple linear regression analysis showed that 58% of the variance in the excitement symptom cluster was explained by a positive association with frontal midline N200 amplitude and an inverse association with right frontal N200 amplitude. The latter was not apparent in the initial correlation, suggesting suppression by the midline activity. These associations were not explained by drug use, medication or negative symptoms. However, the correlation between excitement and midline N200 was stronger in drug users, and that between right frontal N200 and excitement was stronger in nonusers.
CONCLUSION:
Findings support the independent contributions to excitement of mechanisms reflected in midline and right frontal N200 amplitude respectively during the early stages of psychosis.
Accessibility: Document exists in file
Language:
eng
Author:
Sumich, A.
Secondary author(s):
Harris, A., Whitford, T., Hermens, D., Heym, N., Anderson, J., Bloxsom, C., Kibowski, F., Kumari, V.
Document type:
Article
Number of reproductions:
1
Percentiles:
7|2022-03-19
Reference:
Sumich, A., Harris, A., Whitford, T., Hermens, D., Heym, N., ..., Kumari, V. (2018). Neurophysiological correlates of excitement in men with recent-onset psychosis. Psychiatria Danubina, 30(1), 64-71. doi: 10.24869/psyd.2018.64
2-year Impact Factor: 0.683|2018
Times cited: 0|2022-10-24
Indexed document: Yes
Quartile: Q4
Keywords: Psychosis / Recent-onset / Event-related potentials / N200 / Excitement / Drug use

Neurophysiological correlates of excitement in men with recent-onset psychosis

Neurophysiological correlates of excitement in men with recent-onset psychosis