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File112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications2005-012007-11

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders
DocumentFinal report - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders

Reference code: PT/FB/BL-2004-112.01
Location: Arquivo PCA - Pasta 15/2004
Title:
Final report - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Publication year: 2007
URL:
http://www.bial.com/imagem/Bolsa%2011204_21122011.pdf
Abstract/Results: RESULTS:
Two improved versions of a TMS coil designed for stimulation of deep neuronal structures, the new H1 and H2 coils, were built and tested for safety on 31 normal volunteers. Treatments were conducted with H1-coil, H2-coil, Standard (superficial) figure-8 coil and Sham coil at 1, 10 and 20 Hz. Analysis of short clinical assessments protocols and additional safety measurements revealed that TMS stimulation was well tolerated with no major side effects. Overall, the changes were not differential for the four treatment groups and no evidence was found for a possible deterioration in cognitive performance due to the TMS treatments. In some tests transient cognitive improvement were observed, but only with deep TMS.
The H-coils were then used in a clinical study to test for effectiveness and safety on 50 depressed patients, who received daily TMS treatment 5 days per week for 4 consecutive weeks. Stimulation with these coils was well tolerated, with no major side effects or adverse physical outcomes. Compared with the value prior to the start of TMS therapy, 31.3 ± 5.0, the average HAM-D scale dropped significantly to 16.2 ± 9.9 on the day after completion of the therapy. There was no significant difference between the coils, but the H1 coil tended to induce greater antidepressant effects. The CANTAB performed before, during and after the study indicated selective improvement in cognitive functions, especially spatial memory and executive function.
We also showed, using computer models, that an effective way to improve the performance of the H-coils is to combine them with iron cores. Their presence contributes to an overall increase in stimulus intensity in the vicinity of the core, which is more pronounced in deep regions.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Notes:
The final report consists of two progress reports
Author: Miranda, P. C.
Secondary author(s):
Zangen, A., Salvador, R., Cruz, E., Roth, Y.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Depression / Transcranial magnetic stimulation (TMS)

Final report - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications

Final report - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
DocumentThree-dimensional distribution of the electric field induced in the brain by transcranial magnetic stimulation using figure-8 and deep H-coils2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders

Reference code: PT/FB/BL-2004-112.02
Location: Arquivo PCA - Pasta 15/2004
Title:
Three-dimensional distribution of the electric field induced in the brain by transcranial magnetic stimulation using figure-8 and deep H-coils
Publication year: 2007
URL:
http://www.brainsway.com/Brainsway/SendFile.asp?DBID=1&LNGID=1&GID=467
Abstract/Results: ABSTRACT:
The H-coils are a novel development in transcranial magnetic stimulation (TMS), designed to achieve effective stimulation of deep neuronal regions without inducing unbearable fields cortically, thus broadly expanding the potential feasibility of TMS for research and for treating various neurologic disorders. This study compared the field distribution of two H-coil versions, termed H1 and H2, and of a standard figure-of-eight coil. Three-dimensional electrical field distributions of the H1 and H2-coils, designed for effective stimulation of prefrontal regions, and of a standard figure-8 coil, were measured in a head model filled with physiologic saline solution. With stimulator output at 120% of the hand motor threshold, suprathreshold field is induced by the H1-coil at lateral and medial frontal regions at depths of up to 4 to 5 cm, and by the H2-coil at medial prefrontal regions up to 2 to 3 cm, and at lateral frontal regions up to 5 to 6 cm. The figure-8 coil induced suprathreshold field focally under the coil's central segment, at depths of up to 1.5 cm. The ability of the H-coils to stimulate effectively deeper neuronal structures is obtained at the cost of a wider electrical field distribution in the brain. However, the H-coils enable simultaneous stimulation of several brain regions, whereas the depth penetration in each region can be controlled either by adjusting the stimulator output, and/or by varying the distance between various coil elements and the skull.
Accessibility: Document does not exist in file
Language:
eng
Author:
Roth, Y.
Secondary author(s):
Amir, A., Levkovitz, Y., Zangen, A.
Document type:
Article
Number of reproductions:
1
Reference:
Roth, Y., Amir, A., Levkovitz, Y., & Zangen, A. (2007). Three-dimensional distribution of the electric field induced in the brain by transcranial magnetic stimulation using figure-8 and deep H-coils. Journal of Clinical Neurophysiology, 24(1), 31-38. doi: 10.1097/WNP.0b013e31802fa393
2-year Impact Factor: 1.500|2007
Times cited: 225|2022-10-27
Indexed document: Yes
Quartile: Q3
Keywords: Transcranial magnetic stimulation (TMS) / Deep brain stimulation / Electrical field distribution / Motor threshold / Magnetic coil
DocumentA randomized controlled feasibility and safety study of deep transcranial magnetic stimulation2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders

Reference code: PT/FB/BL-2004-112.03
Location: Arquivo PCA - Pasta 15/2004
Title:
A randomized controlled feasibility and safety study of deep transcranial magnetic stimulation
Publication year: 2007
URL:
http://psych.wisc.edu/postlab/readings/Levkovitz2007ClinNeurophys.pdf
Abstract/Results: ABSTRACT:
OBJECTIVE:
The H-coils are a new development in transcranial magnetic stimulation (TMS) research, allowing direct stimulation of deeper neuronal pathways than does standard TMS. This study assessed possible health risks, and some cognitive and emotional effects, of two H-coil versions designed to stimulate deep portions of the prefrontal cortex, using several stimulation frequencies.
METHODS:
Healthy volunteers (n=32) were randomly assigned to one of four groups: each of two H-coil designs (H1/H2), standard figure-8 coil, and sham-coil control. Subjects were tested in a pre-post design, during three increasing (single pulses, 10 Hz, and 20 Hz stimulation sessions, as well as 24-36 h after the last stimulation.
RESULTS:
The major finding of the present study is that stimulation with the novel H-coils was well tolerated, with no adverse physical or neurological outcomes. Computerized cognitive tests found no deterioration in cognitive functions, except for a transient short-term effect of the H1-coil on spatial recognition memory on the first day of rTMS (but not in the following treatment days). On the other hand, spatial working memory was transiently improved by the H2-coil treatment. Finally, the questionnaires showed no significant emotional or mood alterations, except for reports on 'detachment' experienced by subjects treated with the H1-coil.
CONCLUSIONS:
This study provides additional evidence for the feasibility and safety of the two H-coil designs (H1/H2).
SIGNIFICANCE:
The H-coils offer a safe new tool with potential for both research and clinical applications for psychiatric and neurological disorders associated with dysfunctions of deep brain regions.
Accessibility: Document does not exist in file
Language:
eng
Author:
Levkovitz, Y.
Secondary author(s):
Roth, Y., Harel, E. V., Braw, Y., Sheer, A., Zangen, A.
Document type:
Article
Number of reproductions:
1
Reference:
Levkovitz, Y., Roth, Y., Harel, E. V., Braw, Y., Sheer, A., & Zangen, A. (2007). A randomized controlled feasibility and safety study of deep transcranial magnetic stimulation. Clinical Neurophysiology, 118(12), 2730-2744. doi: 10.1016/j.clinph.2007.09.061
2-year Impact Factor: 2.468|2007
Times cited: 104|2022-10-27
Indexed document: Yes
Quartile: Q2
Keywords: Deep transcranial magnetic stimulation / Repetitive transcranial magnetic stimulation (rTMS) / H-coil / Safety / Cognitive / Mood
DocumentHigh permeability cores to optimize the stimulation of deeply located brain regions using transcranial magnetic stimulation2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders

Reference code: PT/FB/BL-2004-112.04
Location: Arquivo PCA - Pasta 15/2004
Title:
High permeability cores to optimize the stimulation of deeply located brain regions using transcranial magnetic stimulation
Publication year: 2009
URL:
http://iopscience.iop.org/0031-9155/54/10/010
Abstract/Results: ABSTRACT:
Efficient stimulation of deeply located brain regions with transcranial magnetic stimulation (TMS) poses many challenges, arising from the fact that the induced field decays rapidly and becomes less focal with depth. We propose a new method to improve the efficiency of TMS of deep brain regions that combines high permeability cores, to increase focality and field intensity, with a coil specifically designed to induce a field that decays slowly with increasing depth. The performance of the proposed design was investigated using the finite element method to determine the total electric field induced by this coil/core arrangement on a realistically shaped homogeneous head model. The calculations show that the inclusion of the cores increases the field's magnitude by as much as 25% while also decreasing the field's decay with depth along specific directions. The focality, as measured by the area where the field's norm is greater than 1/sq.rt.2 of its maximum value, is also improved by as much as 15% with some core arrangements. The coil's inductance is not significantly increased by the cores. These results show that the presence of the cores might make this specially designed coil even more suited for the effective stimulation of deep brain regions.
Accessibility: Document does not exist in file
Language:
eng
Author:
Salvador, R.
Secondary author(s):
Miranda, P. C., Roth, Y., Zangen, A.
Document type:
Article
Number of reproductions:
1
Reference:
Salvador, R., Miranda, P. C., Roth, Y., & Zangen, A. (2009). High permeability cores to optimize the stimulation of deeply located brain regions using transcranial magnetic stimulation. Physics in Medicine and Biology, 54(10), 3113-3128. doi: 10.1088/0031-9155/54/10/010
2-year Impact Factor: 2.781|2009
Times cited: 15|2022-10-27
Indexed document: Yes
Quartile: Q1
Keywords: Psychophysiology / Transcranial magnetic stimulation (TMS) / Deep brain stimulation / Electric field
DocumentThe electric field induced by a new coil specifically designed for activation of deep brain regions2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders

Reference code: PT/FB/BL-2004-112.05
Location: Arquivo PCA - Pasta 15/2004
Title:
The electric field induced by a new coil specifically designed for activation of deep brain regions
Publication year: 2006
Accessibility:
Document exists in file (in CD)
Copyright/Reproduction:
By permission
Language:
eng
Author:
Salvador, R.
Secondary author(s):
Miranda, P. C., Roth, Y., Amir, A., Zangen, A.
Document type:
Unpublished document
Number of reproductions:
1
Reference:
Salvador, R., Miranda, P. C., Roth, Y., Amir, A., & Zangen, A. (2006, August). The electric field induced by a new coil specifically designed for activation of deep brain regions. Poster presented at Biomag2006, the 15th International Conference on Biomagnetism. Vancouver, Bristish Columbia, Canada.
Indexed document: No
Keywords: Psychophysiology / Transcranial magnetic stimulation (TMS) / Electric field / Deep brain stimulation

The electric field induced by a new coil specifically designed for activation of deep brain regions

The electric field induced by a new coil specifically designed for activation of deep brain regions
DocumentHigh-permeability core coils for Transcranial Magnetic Stimulation of deep brain regions2007

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders

Reference code: PT/FB/BL-2004-112.06
Location: Arquivo PCA - Pasta 15/2004
Title:
High-permeability core coils for Transcranial Magnetic Stimulation of deep brain regions
Publication year: 2007
URL:
http://europepmc.org/abstract/MED/18003551
Abstract/Results: ABSTRACT:
Stimulation of deep brain regions with Transcranial Magnetic Stimulation (TMS) may have an important role as a therapy to treat chemical dependency and depression. The coils traditionally used in TMS, however, have a poor performance in stimulating deep neurons. In this work we study the usage of high permeability cores combined with coils specifically designed to induce fields that decay slowly with depth. By using the finite elements method we show that the use of such cores increases the field's magnitude, decreases its decay rate and improves its focality. Such improvements make these high permeability core coils more suited to stimulate deep brain regions.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Salvador, R.
Secondary author(s):
Miranda, P. C., Roth, Y., Zangen, A.
Document type:
Conference paper
Number of reproductions:
1
Reference:
Salvador, R., Miranda, P. C., Roth, Y., & Zangen, A. (2007). High-permeability core coils for Transcranial Magnetic Stimulation of deep brain regions. In Proceedings of the 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2007 (pp. 6653-6656). New York: IEEE. doi: 10.1109/IEMBS.2007.4353885
Times cited: 11|2022-10-22
Indexed document: Yes
Keywords: Psychophysiology / Transcranial magnetic stimulation (TMS) / Deep brain stimulation / Electric field

High-permeability core coils for Transcranial Magnetic Stimulation of deep brain regions

High-permeability core coils for Transcranial Magnetic Stimulation of deep brain regions
DocumentNovas bobinas para estimulação magnética transcraniana de regiões cerebrais profundasn.d.

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders

Reference code: PT/FB/BL-2004-112.07
Location: Arquivo PCA - Pasta 15/2004
Title:
Novas bobinas para estimulação magnética transcraniana de regiões cerebrais profundas
Publication year: n.d.
Accessibility:
Document exists in file
Copyright/Reproduction:
By permission
Language:
por
Notes:
This documents is a final research project as requirement to complete a bachelor's degree
Author: Salvador, R.
Document type:
Unpublished document
Number of reproductions:
1
Reference:
Salvador, R. (n.d.). Novas bobinas para estimulação magnética transcraniana de regiões cerebrais profundas
(Unpublished document). Lisboa: Instituto Superior Técnico, Universidade Técnica de Lisboa.
Indexed document: No
Keywords: Psychophysiology / Transcranial magnetic stimulation (TMS) / Deep brain stimulation

Novas bobinas para estimulação magnética transcraniana de regiões cerebrais profundas

Novas bobinas para estimulação magnética transcraniana de regiões cerebrais profundas
DocumentEstimulação magnética transcraniana em profundidade2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders

Reference code: PT/FB/BL-2004-112.08
Location: Arquivo PCA - Pasta 15/2004
Title:
Estimulação magnética transcraniana em profundidade
Publication year: 2006
Accessibility:
Document exists in file (in CD)
Copyright/Reproduction:
By permission
Language:
por
Author:
Cruz, E.
Document type:
Unpublished document
Number of reproductions:
1
Reference:
Cruz, E. (2006). Estimulação magnética transcraniana em profundidade [Technical report]. Lisboa: Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa.
Indexed document: No
Keywords: Psychophysiology / Transcranial magnetic stimulation (TMS) / Deep brain stimulation / Mu-metal sheets

Estimulação magnética transcraniana em profundidade

Estimulação magnética transcraniana em profundidade
DocumentHigh permeability core coils in transcranial magnetic stimulation of deep brain regionsn.d.

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders

Reference code: PT/FB/BL-2004-112.09
Location: Arquivo PCA - Pasta 15/2004
Title:
High permeability core coils in transcranial magnetic stimulation of deep brain regions
Publication year: n.d.
Accessibility:
Document exists in file (in CD)
Copyright/Reproduction:
By permission
Language:
eng
Author:
Salvador, R.
Secondary author(s):
Miranda, P. C., Roth, Y., Zangen, A.
Document type:
Unpublished document
Number of reproductions:
1
Reference:
Salvador, R., Miranda, P. C., Roth, Y., & Zangen, A. (n. d.). High permeability core coils in transcranial magnetic stimulation of deep brain regions [Technical report].
Indexed document: No
Keywords: Psychophysiology / Transcranial magnetic stimulation (TMS) / Deep brain stimulation / Electric field

High permeability core coils in transcranial magnetic stimulation of deep brain regions

High permeability core coils in transcranial magnetic stimulation of deep brain regions
DocumentImprovement of transcranial magnetic stimulation (TMS) coils for psychiatric applications2008

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-112
Location: Arquivo PCA - Pasta 15/2004
Title:
112 - Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Duration: 2005-01 - 2007-11
Researcher(s):
Pedro Cavaleiro Miranda, Yiftach Roth, Ludovic Correia, Ricardo Salvador, Abraham Zangen
Institution(s): Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa (Portugal)
Contents: Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
CD (progress and financial report 2005, graduation project, letter, consortium agreement - Weizmann )
CD (final report, 2 technical reports, abstract, poster)
DVD (financial report, invoices, statement of expenditure)
Final research project as requirement to complete a bachelor’s degree
Language: eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R., Zangen, A.
Number of reproductions:
1
Keywords:
Psychophysiology / Assessment tools / Intervention / Biopsychological problems / Mental health / Mood disorders

Reference code: PT/FB/BL-2004-112.10
Location: Arquivo PCA - Pasta 15/2004
Title:
Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications
Publication year: 2008
URL:
http://www.bial.com/imagem/Actas_7Simp.pdf
Abstract/Results: ABSTRACT:
OBJECTIVES:
To design and test new coils for transcranial magnetic stimulation of deep brain structures. Efficient stimulation of structures such as the nucleus accumbens and other limbic regions is necessary for the successful application of TMS in psychiatry.
METHODS:
TMS coils specially designed for deep stimulation (H1 and H2 coils) were tested on 31 normal subjects and on 50 drug resistant patients suffering from major depression. Numerical methods were used to predict the electric field induced by these coils and to investigate ways to improve their performance.
RESULTS:
In normal subjects rTMS stimulation at 1, 10 or 20 Hz was well tolerated with no major side effects. Auditory thresholds measured by audiograms indicated no hearing loss of any of the subjects. No evidence was found for a possible deterioration in cognitive performance due to rTMS. No epileptic convulsions were experienced.
TMS treatment 5 days per week for 4 consecutive weeks was well tolerated by the depressed subjects, with no major side effects or adverse physical outcomes. The average HAM-D scale dropped significantly from 31.3 ± 5.0 prior to TMS to 16.2 ± 9.9 on the day after completion of therapy. There was no significant difference between the coils, however the H1 coil tended to induce greater antidepressant effects. The CANTAB performed before, during and after the study indicated selective improvement in cognitive functions, especially spatial memory and executive function.
Numerical calculations based on 3D models of the H1 and H2 coils placed over the head phantom produced results in good agreement with measured values. Clear improvements in coil performance (stimulus intensity, depth and focality) were predicted only when iron cores were added to the coils.
CONCLUSIONS:
The safety and effectiveness of the novel H1 and H2 coils were demonstrated. The use of high permeability cores is the best way to improve the performance of these coils.
PUBLICATIONS:
Roth Y, Amir A, Levkovitz Y, Zangen A, “Three-dimensional distribution of the electric field induced in the brain by transcranial magnetic stimulation using figure-8 and deep H-coils”, J Clin Neurophysiol, 2007, 24:31-
8.; Salvador R, Miranda P C, Roth Y, Zangen A, “High-permeability core coils for Transcranial Magnetic Stimulation of deep brain regions”, 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Lyon, France, August 2007.
Accessibility: Document does not exist in file
Language:
eng
Author:
Miranda, P. C.
Secondary author(s):
Roth, Y., Correia, L., Salvador, R.
Document type:
Conference abstract
Number of reproductions:
1
Reference:
Miranda, P. C., Roth, Y., Correia, L., & Salvador, R. (2008). Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications. In Aquém e além do cérebro. Behind and beyond the brain. Proceedings of the 7th Symposium of Fundação Bial. Porto: Fundação Bial.
Indexed document: No
Keywords: Transcranial magnetic stimulation (TMS) / Stimulation / Deep / Depression / Psychiatry

Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications

Improvement of transcranial magnetic stimulation (TMS) coils for psychiatric applications