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File061 - Translation of neuron-glia interactions in complex cognitive functions2011-052015-07

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-061
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
061 - Translation of neuron-glia interactions in complex cognitive functions
Duration: 2011-05 - 2015-07
Researcher(s):
João Filipe Pedreira de Oliveira, Nuno Sérgio Mendes Dias, Luis Ricardo Monteiro Jacinto
Institution(s): Instituto de Investigação em Ciências da Vida e da Saúde (ICVS), Escola de Ciências da Saúde, Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
3 Articles
1 Poster
Language: eng
Author:
Oliveira, J. F.
Secondary author(s):
Dias, N., Jacinto, L. R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Brain structure and function
DocumentChronic stress disrupts neural coherence between cortico-limbic structures2013

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-061
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
061 - Translation of neuron-glia interactions in complex cognitive functions
Duration: 2011-05 - 2015-07
Researcher(s):
João Filipe Pedreira de Oliveira, Nuno Sérgio Mendes Dias, Luis Ricardo Monteiro Jacinto
Institution(s): Instituto de Investigação em Ciências da Vida e da Saúde (ICVS), Escola de Ciências da Saúde, Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
3 Articles
1 Poster
Language: eng
Author:
Oliveira, J. F.
Secondary author(s):
Dias, N., Jacinto, L. R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Brain structure and function

Reference code: PT/FB/BL-2010-061.02
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
Chronic stress disrupts neural coherence between cortico-limbic structures
Publication year: 2013
URL:
http://www.frontiersin.org/Neural_Circuits/10.3389/fncir.2013.00010/abstract
Abstract/Results: ABSTRACT:
Chronic stress impairs cognitive function, namely on tasks that rely on the integrity of cortico-limbic networks. To unravel the functional impact of progressive stress in cortico-limbic networks we measured neural activity and spectral coherences between the ventral hippocampus (vHIP) and the medial prefrontal cortex (mPFC) in rats subjected to short term stress (STS) and chronic unpredictable stress (CUS). CUS exposure consistently disrupted the spectral coherence between both areas for a wide range of frequencies, whereas STS exposure failed to trigger such effect. The chronic stress-induced coherence decrease correlated inversely with the vHIP power spectrum, but not with the mPFC power spectrum, which supports the view that hippocampal dysfunction is the primary event after stress exposure. Importantly, we additionally show that the variations in vHIP-to-mPFC coherence and power spectrum in the vHIP correlated with stress-induced behavioral deficits in a spatial reference memory task. Altogether, these findings result in an innovative readout to measure, and follow, the functional events that underlie the stress-induced reference memory impairments.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
PT/FB/BL-2008-134.02
Author: Oliveira, J. F.
Secondary author(s):
Dias, N., Correia, M., Gama-Pereira, F., Sardinha, V. M., Lima, A., Oliveira, A. F., Jacinto, L. R., Ferreira, D. S., Silva, A. M., Reis, J. S., Cerqueira, J., Sousa, N.
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Oliveira, J. F., Dias, N., Correia, M., Gama-Pereira, F., Sardinha, V. M., ... Sousa, N. (2013). Chronic stress disrupts neural coherence between cortico-limbic structures. Frontiers in Neural Circuits, 7:10, 1-12. https://doi.org/10.3389/fncir.2013.00010
2-year Impact Factor: 2.950|2013
Times cited: 37|2024-02-02
Indexed document: Yes
Quartile: Q2
Keywords: Chronic stress / Coherence / Power spectrum / Hippocampus / Prefrontal cortex

Chronic stress disrupts neural coherence between cortico-limbic structures

Chronic stress disrupts neural coherence between cortico-limbic structures
DocumentAssessing cognitive function in a rat model of glial pathology2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-061
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
061 - Translation of neuron-glia interactions in complex cognitive functions
Duration: 2011-05 - 2015-07
Researcher(s):
João Filipe Pedreira de Oliveira, Nuno Sérgio Mendes Dias, Luis Ricardo Monteiro Jacinto
Institution(s): Instituto de Investigação em Ciências da Vida e da Saúde (ICVS), Escola de Ciências da Saúde, Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
3 Articles
1 Poster
Language: eng
Author:
Oliveira, J. F.
Secondary author(s):
Dias, N., Jacinto, L. R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Brain structure and function

Reference code: PT/FB/BL-2010-061.03
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
Assessing cognitive function in a rat model of glial pathology
Publication year: 2012
URL:
http://fens.ekonnect.co/FENS_331/poster_35339/program.aspx
Abstract/Results: ABSTRACT:
Astrocytes are being recognized as active elements concerning information flow in the brain, however their role in cognition is still unknown. In this study we aimed to understand the influence of astrocytic function in complex cognitive processes that depend on the medial prefrontal cortex (mPFC). The rationale consisted in analysing the cognitive performance of animals with induced glial pathology in the mPFC. This animal model was obtained by bilateral intracranial injections of L-a-aminoadipate to cause astrocyte ablation in Wistar-Han rats. Cognitive functions dependent on the mPFC, such as attention set-shifting and reversal learning of non-spatial working memory, were assessed by the attentional set-shifting task (ASST). Animals with mPFC-glial pathology showed no differences in learning how to perform the task, however they learnt faster the compound discrimination stages, when compared to the controls. Regarding the reversal learning stages, drug injected animals presented more difficulties than controls. Glial pathology seems to affect the function of neuro-glial networks, which may be translated in altered behavioural outputs.
Accessibility: Document exists in file (poster)
Copyright/Reproduction:
By permission
Language:
eng
Author:
Lima, A.
Secondary author(s):
Reis, M., Cerqueira, J., Sousa, N., Oliveira, J. F.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Lima, A., Reis, M., Cerqueira, J., Sousa, N., & Oliveira, J. F. (2012, July). Assessing cognitive function in a rat model of glial pathology. Poster presented at the 8th FENS Forum Neuroscience, Barcelona, Spain. Abstract retrieved from http://fens.ekonnect.co/FENS_331/poster_35339/program.aspx
Indexed document: No
Keywords: Astrocyte / Cognition / Learning / Prefrontal cortex

Assessing cognitive function in a rat model of glial pathology

Assessing cognitive function in a rat model of glial pathology
DocumentAstrocyte pathology in the prefrontal cortex impairs the cognitive function of rats2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-061
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
061 - Translation of neuron-glia interactions in complex cognitive functions
Duration: 2011-05 - 2015-07
Researcher(s):
João Filipe Pedreira de Oliveira, Nuno Sérgio Mendes Dias, Luis Ricardo Monteiro Jacinto
Institution(s): Instituto de Investigação em Ciências da Vida e da Saúde (ICVS), Escola de Ciências da Saúde, Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
3 Articles
1 Poster
Language: eng
Author:
Oliveira, J. F.
Secondary author(s):
Dias, N., Jacinto, L. R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Brain structure and function

Reference code: PT/FB/BL-2010-061.04
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
Astrocyte pathology in the prefrontal cortex impairs the cognitive function of rats
Publication year: 2014
URL:
http://www.nature.com/mp/journal/vaop/ncurrent/full/mp2013182a.html
Abstract/Results: ABSTRACT:
Interest in astroglial cells is rising due to recent findings supporting dynamic neuron–astrocyte interactions. There is increasing evidence of astrocytic dysfunction in several brain disorders such as depression, schizophrenia or bipolar disorder; importantly these pathologies are characterized by the involvement of the prefrontal cortex and by significant cognitive impairments. Here, to model astrocyte pathology, we injected animals with the astrocyte specific toxin L-a-aminoadipate (L-AA) in the medial prefrontal cortex (mPFC); a behavioral and structural characterization two and six days after the injection was performed. Behavioral data shows that the astrocyte pathology in the mPFC affects the attentional set-shifting, the working memory and the reversal learning functions. Histological analysis of brain sections of the L-AA-injected animals revealed a pronounced loss of astrocytes in the targeted region. Interestingly, analysis of neurons in the lesion sites showed a progressive neuronal loss that was accompanied with dendritic atrophy in the surviving neurons. These results suggest that the L-AA-induced astrocytic loss in the mPFC triggers subsequent neuronal damage leading to cognitive impairment in tasks depending on the integrity of this brain region. These findings are of relevance to better understand the pathophysiological mechanisms underlying disorders that involve astrocytic loss/dysfunction in the PFC.
Accessibility: Document does not exist in file
Language:
eng
Related objects:
PT/FB/BL-2008-134.04
Author: Lima, A.
Secondary author(s):
Sardinha, V. M., Oliveira, A. F., Reis, M., Mota, C., Silva, M., Marques, F., Cerqueira, J., Pinto, L., Sousa, N., Oliveira, J. F.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Lima, A., Sardinha V. M., Oliveira A. F., Reis M., Mota C., Silva, M., . . . Oliveira, J. F. (2014). Astrocyte pathology in the prefrontal cortex impairs the cognitive function of rats. Molecular Psychiatry,19(7), 834-841. https://doi.org/10.1038/mp.2013.182
2-year Impact Factor: 14.496|2014
Times cited: 81|2024-02-02
Indexed document: Yes
Quartile: Q1
Keywords: Aminoadipate / Astrocyte / Cognition / Learning / Prefrontal cortex

Astrocyte pathology in the prefrontal cortex impairs the cognitive function of rats

Astrocyte pathology in the prefrontal cortex impairs the cognitive function of rats
DocumentFinal report - Translation of neuron-glia interactions in complex cognitive functions2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-061
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
061 - Translation of neuron-glia interactions in complex cognitive functions
Duration: 2011-05 - 2015-07
Researcher(s):
João Filipe Pedreira de Oliveira, Nuno Sérgio Mendes Dias, Luis Ricardo Monteiro Jacinto
Institution(s): Instituto de Investigação em Ciências da Vida e da Saúde (ICVS), Escola de Ciências da Saúde, Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
3 Articles
1 Poster
Language: eng
Author:
Oliveira, J. F.
Secondary author(s):
Dias, N., Jacinto, L. R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Brain structure and function

Reference code: PT/FB/BL-2010-061.01
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
Final report - Translation of neuron-glia interactions in complex cognitive functions
Publication year: 2015
URL:
https://www.bial.com/imagem/Bolsa6110_22092015.pdf
Abstract/Results: ABSTRACT:
BACKGROUND
The classical paradigm that cognitive processing is exclusively neuronal has been challenged in the past ten years by an exciting body of evidence. Indeed, the importance of glial cells is rising due to emerging data supporting dynamic neuron-glia interactions, in which a cross-talk between astrocytes and neurons complements and modulates the communication between pre- and post-synaptic structures.
AIM
The main research objective of this project is to assess the interplay between astrocytes and neurons underlying cognitive function in the brain.
METHODS
We have used complementary state-of-the-art techniques such as in vivo electrophysiology, innovative behavior, anatomical and molecular analysis, to seek a role of astrocytes in the computation of cognitive functions.
RESULTS/CONCLUSIONS
Astrocytes appear as critical elements of the neuroglial network, whose function is required for the normal hippocampal function. This information accounts for new knowledge on the cognitive computation and this new player may account also for the cognitive decline observed for instance in ageing or pathological processes, arising as a possible therapeutic target for the treatment of prevention of cognitive deficits.
Accessibility: Document exists in file
Language:
eng
Author:
Oliveira, J. F.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Astrocyte / Cognition / Neural circuits / Behavior / Electrophysiology

Final report - Translation of neuron-glia interactions in complex cognitive functions

Final report - Translation of neuron-glia interactions in complex cognitive functions
DocumentDo stars govern our actions? Astrocyte involvement in rodent behavior2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-061
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
061 - Translation of neuron-glia interactions in complex cognitive functions
Duration: 2011-05 - 2015-07
Researcher(s):
João Filipe Pedreira de Oliveira, Nuno Sérgio Mendes Dias, Luis Ricardo Monteiro Jacinto
Institution(s): Instituto de Investigação em Ciências da Vida e da Saúde (ICVS), Escola de Ciências da Saúde, Universidade do Minho, Braga (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
3 Articles
1 Poster
Language: eng
Author:
Oliveira, J. F.
Secondary author(s):
Dias, N., Jacinto, L. R.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Brain structure and function

Reference code: PT/FB/BL-2010-061.05
Location: Arquivo PCA - Pastas 17/2010 e 18/2010
Title:
Do stars govern our actions? Astrocyte involvement in rodent behavior
Publication year: 2015
URL:
http://www.sciencedirect.com/science/article/pii/S0166223615001733
Abstract/Results: ABSTRACT:
Astrocytes have emerged as important partners of neurons in information processing. Important progress has been made in the past two decades in understanding the role of astrocytes in the generation of neuron–astrocyte network outputs resulting in behavior. We review evidence for astrocyte involvement across four different behavioral domains: cognition, emotion, motor, and sensory processing. Accumulating evidence from animal models has provided a wealth of data that largely supports a direct involvement of astrocytes on diverse aspects of behavior. The development of tools for selectively controlling the temporal and spatial properties of astrocyte activity will help to consolidate our knowledge of the mechanisms underlying this involvement.
Accessibility: Document does not exist in file
Language:
eng
Author:
Oliveira, J. F.
Secondary author(s):
Sardinha, V. M., Guerra-Gomes, S., Araque, A., Sousa, N.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Oliveira, J. F., Sardinha, V. M., Guerra-Gomes, S., Araque, A., & Sousa, N. (2015). Do stars govern our actions? Astrocyte involvement in rodent behavior. Trends in Neurosciences, 38(9), 535-549. https://doi.org/10.1016/j.tins.2015.07.006
2-year Impact Factor: 12.504|2015
Times cited: 123|2024-02-07
Indexed document: Yes
Quartile: Q1
Keywords: Astrocyte / Behavior / Cognition / Emotion / Motor / Sensorial