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File072 - Neurocognitive mechanisms supporting the influence of memory on visual attention in healthy and disease2011-04 2013-10

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-072
Location: Arquivo PCA - Pasta 8/2010
Title:
072 - Neurocognitive mechanisms supporting the influence of memory on visual attention in healthy and disease
Duration: 2011-04 - 2013-10
Researcher(s):
José Miguel Pinto Cardoso de Bourbon Teles, David Soto, Paul Bentley
Institution(s): Centre for Neuroscience, Faculty of Medicine, Department of Neuroscience and Mental Health, Imperial College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Poster
Language: eng
Author:
de Bourbon Teles, J.
Secondary author(s):
Soto, D., Bentley, P.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Attention / Memory / Brain structure and function / Biopsychological problems / Diseases/Injuries

DocumentFinal report - Neural substrates supporting the influence of working memory contents on visual attention2013

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-072
Location: Arquivo PCA - Pasta 8/2010
Title:
072 - Neurocognitive mechanisms supporting the influence of memory on visual attention in healthy and disease
Duration: 2011-04 - 2013-10
Researcher(s):
José Miguel Pinto Cardoso de Bourbon Teles, David Soto, Paul Bentley
Institution(s): Centre for Neuroscience, Faculty of Medicine, Department of Neuroscience and Mental Health, Imperial College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Poster
Language: eng
Author:
de Bourbon Teles, J.
Secondary author(s):
Soto, D., Bentley, P.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Attention / Memory / Brain structure and function / Biopsychological problems / Diseases/Injuries

Reference code: PT/FB/BL-2010-072.01
Location: Arquivo PCA - Pasta 8/2010
Title:
Final report - Neural substrates supporting the influence of working memory contents on visual attention
Publication year: 2013
URL:
http://www.bial.com/imagem/72-10-20131212.pdf
Abstract/Results: RESULTS:
In the research project we present causal evidence from a lesion study with rare thalamic patients that the anterior ventrolateral (VL) region plays a pivotal role in linking mnemonic and attention control functions in the human brain. Subsequent fMRI work with healthy volunteers further demonstrated how the role of anterior VL thalamus in cognitive control may be shaped by experience-dependent learning, namely, in task contexts where the association between memory contents and the incoming perceptual data needs to be learned in order for memory to guide search behavior.
Together, these findings provide new and unique insight into the functional role of thalamic structures for high-level behavioral control, critically, for the biasing of attentional selection through memory and learning. The results furthermore stress the importance of characterizing the functional role of subcortical nuclei, in addition to cortical systems (e.g. parietofrontal), for a complete understanding of the mechanisms of attention and cognitive control.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Notes:
The final report consists of the doctoral thesis of the project leader
Author: de Bourbon Teles, J.
Document type:
Doctoral thesis. Final report
Number of reproductions:
1
Reference:
de Bourbon Teles, J. (2013). Neural substrates supporting the influence of working memory contents on visual attention (Unpublished doctoral thesis). Division of Brain Sciences, Imperial College London, England, UK.
Indexed document: No
Keywords: Working memory / Visual attention / Thalamus / Stroke patients / Superior frontal gyrus / Transcranial direct current stimulation (TDCS) / Functional magnetic resonance imaging (fMRI)

Final report - Neural substrates supporting the influence of working memory contents on visual attention

Final report - Neural substrates supporting the influence of working memory contents on visual attention

DocumentThalamic lesions impair memory guidance of visual selection2011

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-072
Location: Arquivo PCA - Pasta 8/2010
Title:
072 - Neurocognitive mechanisms supporting the influence of memory on visual attention in healthy and disease
Duration: 2011-04 - 2013-10
Researcher(s):
José Miguel Pinto Cardoso de Bourbon Teles, David Soto, Paul Bentley
Institution(s): Centre for Neuroscience, Faculty of Medicine, Department of Neuroscience and Mental Health, Imperial College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Poster
Language: eng
Author:
de Bourbon Teles, J.
Secondary author(s):
Soto, D., Bentley, P.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Attention / Memory / Brain structure and function / Biopsychological problems / Diseases/Injuries

Reference code: PT/FB/BL-2010-072.02
Location: Arquivo PCA - Pasta 8/2010
Title:
Thalamic lesions impair memory guidance of visual selection
Publication year: 2011
URL:
http://www.the-bns.org/resources/11_11+BNS+Abstracts+Final.pdf
Abstract/Results: ABSTRACT:
OBJECTIVE:
Functional magnetic resonance imaging (fMRI) research suggests that guidance of attention from the contents of working memory (WM) engages a complex network including frontal areas in dorsolateral prefrontal cortex (DLPFC), superior frontal gyrus (SFG), middle temporal regions, thalamic nuclei and occipital visual cortex. However, evidence from fMRI is only correlational and therefore it is difficult to determine which of the identified brain regions are necessary and causally involved in WM guidance of attention. This issue was addressed in a lesion study with focal-lesion stroke patients.
METHODS:
A total of 67 patients were tested. Patients were required to perform a visual search task for a target object presented amongst distracters. In the valid condition the colour of the sought after target was pre-cued by a verbal cue presented prior to the search display. On neutral trials, the patients did not receive any cue prior to search. Voxel-based lesion-symptom mapping (VLSM) analyses were carried out to relate lesion anatomy to search behaviour.
RESULTS:
The VLSM analyses revealed that patients with thalamic lesions (N=4) showed no memory cueing effect of search despite having intact memory performance in a control memory task. In contrast, the control patients were able to use the memory cue to guide attention towards the target, as indexed by faster reaction times on valid relative to invalid trials.
CONCLUSION:
The findings support the role of the thalamus in controlling visual attention, specifically in guiding attention based on relevant information held in memory.
Accessibility: Document exists in file (poster)
Copyright/Reproduction:
By permission
Language:
eng
Notes:
Abstract and respective poster in attachment
Author: de Bourbon Teles, J.
Secondary author(s):
Bentley, P., Soto, D.
Document type:
Online abstract
Number of reproductions:
1
Reference:
de Bourbon Teles, J., Bentley, P., & Soto, D. (2011, November). Thalamic lesions impair memory guidance of visual selection. Poster presented at the British Neuropsychological Society (BNS) Autumn meeting 2011, London, England. Abstract retrieved from http://www.the-bns.org/resources/11_11+BNS+Abstracts+Final.pdf
Indexed document: No
Keywords: Stroke patients / Visual attention / Working memory / Voxel-based lesion-symptom mapping (VLSM) / Thalamus

Abstract

Abstract

Poster

Poster

DocumentThalamic control of human attention driven by memory and learning2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-072
Location: Arquivo PCA - Pasta 8/2010
Title:
072 - Neurocognitive mechanisms supporting the influence of memory on visual attention in healthy and disease
Duration: 2011-04 - 2013-10
Researcher(s):
José Miguel Pinto Cardoso de Bourbon Teles, David Soto, Paul Bentley
Institution(s): Centre for Neuroscience, Faculty of Medicine, Department of Neuroscience and Mental Health, Imperial College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Poster
Language: eng
Author:
de Bourbon Teles, J.
Secondary author(s):
Soto, D., Bentley, P.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Attention / Memory / Brain structure and function / Biopsychological problems / Diseases/Injuries

Reference code: PT/FB/BL-2010-072.03
Location: Arquivo PCA - Pasta 8/2010
Title:
Thalamic control of human attention driven by memory and learning
Publication year: 2014
URL:
http://www.cell.com/current-biology/abstract/S0960-9822(14)00316-9
Abstract/Results: ABSTRACT:
The role of the thalamus in high-level cognition—attention, working memory (WM), rule-based learning, and decision making—remains poorly understood, especially in comparison to that of cortical frontoparietal networks [1–3]. Studies of visual thalamus have revealed important roles for pulvinar and lateral geniculate nucleus in visuospatial perception and attention [4–10] and for mediodorsal thalamus in oculomotor control [11]. Ventrolateral thalamus contains subdivisions devoted to action control as part of a circuit involving the basal ganglia [12, 13] and motor, premotor, and prefrontal cortices [14], whereas anterior thalamus forms a memory network in connection with the hippocampus [15]. This connectivity profile suggests that ventrolateral and anterior thalamus may represent a nexus between mnemonic and control functions, such as action or attentional selection. Here, we characterize the role of thalamus in the interplay between memory and visual attention. We show that ventrolateral lesions impair the influence of WM representations on attentional deployment. A subsequent fMRI study in healthy volunteers demonstrates involvement of ventrolateral and, notably, anterior thalamus in biasing attention through WM contents. To further characterize the memory types used by the thalamus to bias attention, we performed a second fMRI study that involved learning of stimulus-stimulus associations and their retrieval from long-term memory to optimize attention in search. Responses in ventrolateral and anterior thalamic nuclei tracked learning of the predictiveness of these abstract associations and their use in directing attention. These findings demonstrate a key role for human thalamus in higher-level cognition, notably, in mnemonic biasing of attention.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
de Bourbon Teles, J.
Secondary author(s):
Bentley, P., Koshino, S., Shah, K., Dutta, A., Malhotra, P., Egner, T., Husain, M., Soto, D.
Document type:
Article
Number of reproductions:
1
Percentiles:
4|2022-03-19
Reference:
de Bourbon Teles, J., Bentley, P., Koshino, S., Shah, K., Dutta, A., Malhotra, P., . . . Soto, D. (2014). Thalamic control of human attention driven by memory and learning. Current Biology, 24(9), 993-999. doi: 10.1016/j.cub.2014.03.024
2-year Impact Factor: 9.571|2014
Times cited: 60|2022-05-21
Indexed document: Yes
Quartile: Q1
Keywords: Thalamus / Memory / Visual attention / Learning

Thalamic control of human attention driven by memory and learning

Thalamic control of human attention driven by memory and learning

DocumentAssessing the role of the left dorsal frontal cortex in working memory guidance: attentional or mnemonic? A neurostimulation study2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-072
Location: Arquivo PCA - Pasta 8/2010
Title:
072 - Neurocognitive mechanisms supporting the influence of memory on visual attention in healthy and disease
Duration: 2011-04 - 2013-10
Researcher(s):
José Miguel Pinto Cardoso de Bourbon Teles, David Soto, Paul Bentley
Institution(s): Centre for Neuroscience, Faculty of Medicine, Department of Neuroscience and Mental Health, Imperial College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Poster
Language: eng
Author:
de Bourbon Teles, J.
Secondary author(s):
Soto, D., Bentley, P.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Attention / Memory / Brain structure and function / Biopsychological problems / Diseases/Injuries

Reference code: PT/FB/BL-2010-072.04
Location: Arquivo PCA - Pasta 8/2010
Title:
Assessing the role of the left dorsal frontal cortex in working memory guidance: attentional or mnemonic? A neurostimulation study
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/abs/pii/S0306452219303057?via%3Dihub
Abstract/Results: ABSTRACT
Perceptual selection can be guided by the contents of working memory (WM). Neuroimaging and neuropsychological data points to a role of a fronto-parietal and fronto-thalamic networks in WM guidance. Here we assessed the effect of transcranial direct current stimulation of the left dorsal frontal cortex (lDFC) in a combined WM/attention paradigm. We asked the extent to which the lDFC is implicated in mnemonic and selective attention functions during WM guidance of behaviour. Observers were asked to keep information in memory while searching for a visual target, while the validity of WM contents for the search task varied. We tested the effects of lDFC-tDCS on the strength of WM guidance of search, whether any tDCS effect is dependent on the amount of WM load, and whether lDFC-tDCS primarily influences how WM contents are retained, the process of selective attention in search task, or both. Consistent with prior behavioural findings, we found that (i) selection of items that matched the contents of WM was facilitated relative to non-matching items and (ii) this WM guidance effect was reduced when the level processing/cognitive load in WM was higher. Notably, across two experiments we found that lDFC-tDCS modulated WM guidance of visual selection in the context of high processing loads in WM. No effects of tDCS were observed in WM accuracy. These findings demonstrate that the role of the left dorsal frontal cortex in WM guidance is associated with selective attentional control rather than mnemonic processing.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
de Bourbon Teles, J.
Secondary author(s):
Soto, D.
Document type:
Article
Number of reproductions:
1
Percentiles:
7|2022-03-19
Reference:
de Bourbon Teles, J., & Soto, D. (2019). Assessing the role of the left dorsal frontal cortex in working memory guidance: attentional or mnemonic? A neurostimulation study. Neuroscience, 411, 140-149. doi: 10.1016/j.neuroscience.2019.04.049
2-year Impact Factor: 3.056|2019
Times cited: 3|2022-05-21
Indexed document: Yes
Quartile: Q2
Keywords: Working memory / Attention / Vision / tDCS / Frontal / Search