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File176 - Dopaminergic regulation of dietary learning in humans and rodents2011-072014-07

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

DocumentO-41 - Intravascular food reward2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.02
Location: Arquivo PCA - Pasta 14/2010
Title:
O-41 - Intravascular food reward
Publication year: 2012
URL:
http://www.sciencedirect.com/science/article/pii/S092493381274141X
Abstract/Results: ABSTRACT:
INTRODUCTION:
We recently found that, in mice, independently of orosensory input, sucrose consumption is sufficient to condition the development of spout preferences and dopamine release in the ventral striatum.
OBJECTIVES:
To clarify if the appetitive behavioral and dopaminergic responses to the postingestive effects of calorie-containing sugars reflect preabsorptive or postabsorptive events.
AIMS:
To understand if endovenous injection of glucose is sufficient to condition spout preferences and dopamine release.
METHODS:
Measurements of the behavioural, metabolic and neurochemical effects of the administration of glucose solutions, enterically, and in the jugular (JV) or hepatic-portal (HPV) veins of rats.
RESULTS:
High concentration glucose solutions administered in the JV were sufficient to condition spout preferences in a two-bottle behavioral task. Additionally, a low concentration glucose solution conditioned robust behavioral responses when administered in the HPV, but not the JV. Finally, using fast-scan cyclic voltammetry we found that, in accordance to behavioral findings, a low concentration glucose solution caused an increase of spontaneous dopamine release events in the nucleus accumbens shell when administered in the HPV, but not the JV.
CONCLUSIONS:
The postabsorptive effects of glucose are sufficient to mimic the behavioral and dopaminergic responses that result from sugar consumption. Furthermore, glycemia levels in the HPV contribute more significantly for this effect than systemic glycemia, arguing for the participation of an intra-abdominal visceral sensor for glucose.
Accessibility: Document does not exist in file
Language:
eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Roberts, C. D., Walker, Q. D., Luo, B., Kuhn, C., Simon, A., Nicolelis, M.
Document type:
Abstract
Number of reproductions:
1
Reference:
Oliveira-Maia, A. J., Roberts, C. D., Walker, Q. D., Luo, B., Kuhn, C., Simon, A., & Nicolelis, M. (2012). O-41 - Intravascular food reward. European Psychiatry, 27(Suppl. 1), 1. https://doi.org/10.1016/S0924-9338(12)74141-X
Indexed document: Yes
Keywords: Dopamine / Glucose

DocumentThe (un)pleasant intensity of taste: a glimpse into obesity2012

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.03
Location: Arquivo PCA - Pasta 14/2010
Title:
The (un)pleasant intensity of taste: a glimpse into obesity
Publication year: 2012
URL:
http://www.iaso.org/site_media/uploads/CON_OMH_program_F_6.pdf
Abstract/Results: ABSTRACT:
The relevance of orosensory factors for the pathophysiology of obesity were suggested by the report of changes in taste sensitivity in obese patients, after gastric bypass surgery. However, it is unclear if such changes are specific to this intervention. Here we report on taste intensity and pleasantness for sweet (sucrose), bitter (quinine), sour (citric acid) and salty (sodium chloride tastants, measured in severely obese patients, before and/or after a diet and exercise weight-loss program. Other measurements, such as the Beck Depression Scale, were also conducted. When compared to non-obese controls, we found that quinine and sucrose have a more intense and, respectively, unpleasant (bitter) or pleasant (sweet) taste in obese subjects. However, the effect for sweet taste seems to be, at least partially, dependent on the relationship between obesity and depression. Preliminary analyses in patients tested before and after weightloss further suggest that these taste changes are reversible. Additional experiments are now necessary to directly compare taste changes after surgical and behavioral weight-loss programs.
Accessibility: Document does not exist in file
Language:
eng
Author:
Fernandes, A.
Secondary author(s):
Paixão, V., Branco, T., Martins, S., Costa, R. M., Oliveira-Maia, A. J.
Document type:
Abstract book
Number of reproductions:
1
Reference:
Fernandes, A., Paixão, V., Branco, T., Martins, S., Costa, R. M., & Oliveira-Maia, A. J. (2012). The (un)pleasant intensity of taste: a glimpse into obesity. In Conference program of Hot Topic Conference Obesity & Mental Health (p. 10). Toronto, Canada: International Association for the Study of Obesity (IASO)
Indexed document: No
Keywords: Obesity / Taste sensitivity / Depression / Weight loss

The (un)pleasant intensity of taste: a glimpse into obesity

The (un)pleasant intensity of taste: a glimpse into obesity

DocumentImpulse control disorders in Parkinson's disease: crossroads between neurology, psychiatry and neuroscience2013

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.04
Location: Arquivo PCA - Pasta 14/2010
Title:
Impulse control disorders in Parkinson's disease: crossroads between neurology, psychiatry and neuroscience
Publication year: 2013
URL:
http://iospress.metapress.com/content/e1642885x17hu14n/?genre=article&issn=0953-4180&volume=27&issue=4&spage=547
Abstract/Results: ABSTRACT:
Non-motor symptoms contribute significantly to Parkinson's disease (PD) related disability. Impulse control disorders (ICDs) have been recently added to the behavioural spectrum of PD-related non-motor symptoms. Such behaviours are characterized by an inappropriate drive to conduct repetitive behaviours that are usually socially inadequate or result in harmful consequences. Parkinson disease impulse control disorders (PD-ICDs) have raised significant interest in the scientific and medical community, not only because of their incapacitating nature, but also because they may represent a valid model of ICDs beyond PD and a means to study the physiology of drive, impulse control and compulsive actions in the normal brain. In this review, we discuss some unresolved issues regarding PD-ICDs, including the association with psychiatric co-morbidities such as obsessive-compulsive disorder and with dopamine related side effects, such as hallucinations and dyskinesias; the relationship with executive cognitive dysfunction; and the neural underpinnings of ICDs in PD. We also discuss the contribution of neuroscience studies based on animal-models towards a mechanistic explanation of the development of PD-ICDs, specifically regarding corticostriatal control of goal directed and habitual actions.
Accessibility: Document does not exist in file
Language:
eng
Author:
Bugalho, P.
Secondary author(s):
Oliveira-Maia, A. J.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Bugalho, P., & Oliveira-Maia, A. J. (2013). Impulse control disorders in Parkinson's disease: crossroads between neurology, psychiatry and neuroscience. Behavioural Neurology, 27(4), 547-557. https://doi.org/10.3233/BEN-129019
2-year Impact Factor: 1.642|2013
Times cited: 12|2024-02-02
Indexed document: Yes
Quartile: Q3
Keywords: Parkinson's disease / Impulse control disorders / Non-motor symptoms / Frontostriatal circuits / Dopamine

Impulse control disorders in Parkinson's disease: crossroads between neurology, psychiatry and neuroscience

Impulse control disorders in Parkinson's disease: crossroads between neurology, psychiatry and neuroscience

DocumentExploring the effects of depression and treatment of depression in reinforcement learning2013

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.05
Location: Arquivo PCA - Pasta 14/2010
Title:
Exploring the effects of depression and treatment of depression in reinforcement learning
Publication year: 2013
URL:
http://www.frontiersin.org/Integrative_Neuroscience/10.3389/fnint.2013.00072/full
Accessibility: Document does not exist in file
Language:
eng
Author:
Castro-Rodrigues, P.
Secondary author(s):
Oliveira-Maia, A. J.
Document type:
Article
Number of reproductions:
1
Reference:
Castro-Rodrigues, P., & Oliveira-Maia, A. J. (2013). Exploring the effects of depression and treatment of depression in reinforcement learning. Frontiers in Integrative Neuroscience, 7: 72. https://doi.org/10.3389/fnint.2013.00072
2-year Impact Factor: N/A
Impact factor notes: Impact factor computed since 2018
Times cited: N/A
Indexed document: Yes
Quartile: N/A
Keywords: Depression / SSRI antidepressants / Reinforcement (Psychology) / Punishment / Reward

Exploring the effects of depression and treatment of depression in reinforcement learning

Exploring the effects of depression and treatment of depression in reinforcement learning

DocumentFinal report - Dopaminergic regulation of dietary learning in humans and rodents2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.01
Location: Arquivo PCA - Pasta 14/2010
Title:
Final report - Dopaminergic regulation of dietary learning in humans and rodents
Publication year: 2014
URL:
https://www.bial.com/imagem/Bolsa17610_18112014.pdf
Abstract/Results: ABSTRACT:
BACKGROUND:
The postingestive effects of food stimulate food intake. Dopamine is critically involved in encoding food reward, including postingestive reward.
AIMS:
We proposed to explore the possibility of conditioning flavor-nutrient associations in humans and, in parallel, use invasive tools in mice to explore the relevance of dopaminergic neuron activity in the VTA for nutrient conditioning.
METHODS:
To test flavour-nutrient conditioning in human subjects, consumption levels and pleasantness ratings of flavoured yoghurts were recorded prior to and after a conditioning protocol where one flavour was paired to delivery of a tasteless carbohydrate. In mice, we established instrumental learning paradigms where postingestive feedback was isolated using intragastric infusion of sugars, contingent upon lever pressing, or using trpm5 KO mice, a transgenic model with deficits in orosensory processing of sweet taste. Finally, cell-type specific deletion of NMDAR1 was performed in VTA dopamine neurons to abolish phasic bursting of these neurons.
RESULTS:
In healthy human volunteers the conditioning process did not change flavour pleasantness ratings. However, after conditioning there was increased preference for carbohydrate-paired flavours when preference was calculated according to consumption levels, rather than pleasantness. In mice, caloric postingestive feedback was sufficient to sustain instrumental responses, and bursting activity of VTA dopamine neurons is necessary for such to occur.
CONCLUSIONS:
Nutrient value modulates instrumental responses and food choice independently of orosensory and olfactory cues, in a process that depends on activity patterns of VTA dopamine neurons.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Instrumental conditioning / Flavor-nutrient conditioning / Postingestive reward / Dopamine / Ventral tegmental area

DocumentEffects of weight-loss surgery in gustatory function2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.05
Location: Arquivo PCA - Pasta 14/2010
Title:
Effects of weight-loss surgery in gustatory function
Publication year: 2014
URL:
http://fens2014.meetingxpert.net/FENS_427/poster_103790/program.aspx
Abstract/Results: ABSTRACT:
While it has been suggested that weight-loss approaches could impact gustatory function, this question hasn´t been addressed in a longitudinal design. Here, we proposed to analyze changes in gustatory responses resulting from weight loss interventions. Specifically, we tested individuals involved in obesity treatment programs, before and at several time-points after one of two different interventions: i) 35 participants were undergoing intensive lifestyle modification of (diet + exercise), ii) 50 participants proposed for weight-loss surgery. Data was also compared to that obtained from 29 non-obese individuals. We assessed gustatory function using electrogustometry as well as subjective ratings of taste intensity and pleasantness on visual analogue scales. We found a significant positive correlation between BMI and mean sweet intensity ratings (r = 0.20; p = 0.02). Participants in the lifestyle modification program showed significant differences in sweet and salt pleasantness ratings, but not intensity, before and after weight loss. Longitudinal data collection after weight-loss surgery is on-going. However, even with a small number of subjects, after surgery we found scores on the Power of Food Scale and Food Addiction Scale to be significantly reduced. Our data suggests that gustatory function, in particular for sweet taste, is related to obesity and is modified after weight loss. In ongoing experiments we expect to assess to what degree weight loss is associated to changes in reward-related feeding behaviors.
Accessibility: Document does not exist in file
Language:
eng
Author:
Camacho, M.
Secondary author(s):
Fernandes, A., Castro, C., Branco, T., Costa, R. M., Oliveira-Maia, A. J.
Document type:
Online abstract
Number of reproductions:
1
Reference:
Camacho, M., Fernandes, A., Castro, C., Branco, T., Costa, R. M., & Oliveira-Maia, A. J. (2014, July). Effects of weight-loss surgery in gustatory function. Poster presented at the 9th FENS Forum of European Neuroscience, Milan, Italy. Abstract retrieved from http://fens2014.meetingxpert.net/FENS_427/poster_103790/program.aspx
Indexed document: No
Keywords: Weight loss / Taste sensitivity

DocumentAssociation between hedonic hunger and body-mass index versus obesity status2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.06
Location: Arquivo PCA - Pasta 14/2010
Title:
Association between hedonic hunger and body-mass index versus obesity status
Publication year: 2018
URL:
https://www.nature.com/articles/s41598-018-23988-x
Abstract/Results: ABSTRACT:
Obesity-associated differences in hedonic hunger, while consistently reported, have not been adequately quantified, with most studies failing to demonstrate strong correlations between Body Mass Index (BMI) and hedonic hunger indicators. Here, we quantified and assessed the nature of the relationship between hedonic hunger and BMI, in a cross-sectional study using the Portuguese version of the PFS (P-PFS) to measure hedonic hunger. Data were collected from 1266 participants belonging to non-clinical, clinical (candidates for weight-loss surgery) and population samples. Across samples, significant but weak positive associations were found between P-PFS scores and BMI, in adjusted linear regression models. However, in logistic regression models of data from the clinical and non-clinical samples, the P-PFS Food Available domain score was significantly and robustly associated with belonging to the clinical sample (OR=1.8, 95%CI: 1.2–2.8; p=0.008), while in the population sample it was associated to being obese (OR=2.1, 95%CI: 1.6–2.7; p<0.001). Thus, hedonic hunger levels are associated with obesity status with the odds of being obese approximately doubling for each unit increase in the P-PFS Food Available score.
Accessibility: Document exists in file
Language:
eng
Author:
Ribeiro, G.
Secondary author(s):
Camacho, M., Santos, O., Pontes, C., Torres, S., Oliveira-Maia, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
5
Reference:
Ribeiro, G., Camacho, M., Santos, O., Pontes, C., Torres, S., & Oliveira-Maia, A. (2018). Association between hedonic hunger and body-mass index versus obesity status. Scientific Reports, 8: 5857. https://doi.org/10.1038/s41598-018-23988-x
2-year Impact Factor: 4.011|2018
Times cited: 27|2024-02-09
Indexed document: Yes
Quartile: Q1
Keywords: Obesity / Hedonic hunger

Association between hedonic hunger and body-mass index versus obesity status

Association between hedonic hunger and body-mass index versus obesity status

DocumentEnhanced sweet taste sensitivity in candidates for bariatric surgery2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.07
Location: Arquivo PCA - Pasta 14/2010
Title:
Enhanced sweet taste sensitivity in candidates for bariatric surgery
Publication year: 2019
URL:
https://www.karger.com/Article/PDF/497797
Abstract/Results: ABSTRACT
INTRODUCTION
While taste has been suggested as a potential determinant of feeding behavior in obesity, the supporting evidence, namely of altered sensitivity for sweet taste in obese relative to lean individuals, is inconsistent. Furthermore, such evidence has typically been obtained in studies including only small sample sizes, and with substantial methodological heterogeneity. Importantly, potential associations between taste perception and measures of reward-related feeding behavior remain undetermined.
METHODS
A cross-sectional study was conducted to compare 212 patients with severe obesity, on the waiting list for bariatric surgery, and 94 healthy individuals. Psychophysical gustatory parameters, namely intensity and pleasantness ratings of sour, salt, sweet and bitter tastants, and taste thresholds as assessed with electrogustometry, were determined. Reward-related feeding behavior was assessed using self-rated psychometric scales.
RESULTS
In addition to having a higher BMI, bariatric patients were older, more frequently female and had higher self-rated depression scores than their respective controls. Logistic regressions to assess the likelihood of belonging to the bariatric group were thus adjusted for age and gender, in addition to type II diabetes, education level and research center. In these analyses we found that higher taste thresholds and higher sweet intensity ratings were associated with belonging to the bariatric group (1.03<OR=1.04, both p<0.05), as were higher ratings for hedonic hunger, food addiction symptom scores, restrained and emotional eating (1.94<OR=4.27, all p<0.01), and lower alcohol acceptance (OR = 0.91, p = 0.001). In final exploratory analyses of potential linear relationships between the variables associated with the obese status, while hedonic hunger, food addiction or emotional eating were strongly inter-related, they were not associated with sweet intensity, that in turn had a closer relationship with restrained eating and alcohol acceptance.
CONCLUSION
Here we found that subjects with severe obesity report higher sweet taste intensity ratings than healthy study volunteers. Furthermore, while self-report measures of reward-related feeding behavior seem to assess a similar construct, sweet intensity was not associated with these variables, and may represent a separate obesity-related dimension.
Accessibility: Document exists in file
Language:
eng
Author:
Ribeiro, G.
Secondary author(s):
Torres, S., Fernandes, A. B., Camacho, M., Oliveira Maia, A. J., Study Group, F.
Document type:
Abstract
Number of reproductions:
1
Reference:
Ribeiro, G., Torres, S., Fernandes, A. B., Camacho, M., Oliveira Maia, A. J., & Study Group, F. (2019). Enhanced sweet taste sensitivity in candidates for bariatric surgery. Obesity Facts, 12(Suppl.1), 22-23.
Indexed document: Yes
Keywords: Obesity / Sweet taste

Enhanced sweet taste sensitivity in candidates for bariatric surgery

Enhanced sweet taste sensitivity in candidates for bariatric surgery

DocumentPostingestive modulation of food seeking depends on vagus-mediated dopamine neuron activity2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.08
Location: Arquivo PCA - Pasta 14/2010
Title:
Postingestive modulation of food seeking depends on vagus-mediated dopamine neuron activity
Publication year: 2020
URL:
https://www.cell.com/neuron/pdf/S0896-6273(20)30216-6.pdf?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627320302166%3Fshowall%3Dtrue
Abstract/Results: ABSTRACT:
Postingestive nutrient sensing can induce food preferences. However, much less is known about the ability of postingestive signals to modulate food-seeking behaviors. Here we report a causal connection between postingestive sucrose sensing and vagus-mediated dopamine neuron activity in the ventral tegmental area (VTA), supporting food seeking. The activity of VTA dopamine neurons increases significantly after administration of intragastric sucrose, and deletion of the NMDA receptor in these neurons, which affects bursting and plasticity, abolishes lever pressing for postingestive sucrose delivery. Furthermore, lesions of the hepatic branch of the vagus nerve significantly impair postingestive-dependent VTA dopamine neuron activity and food seeking, whereas optogenetic stimulation of left vagus nerve neurons significantly increases VTA dopamine neuron activity. These data establish a necessary role of vagus-mediated dopamine neuron activity in postingestive-dependent food seeking, which is independent of taste signaling.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Fernandes, A. B.
Secondary author(s):
Alves da Silva, J., Almeida, J., Cui, G., Gerfen, C. R. , Costa, R. M. , Oliveira-Maia, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Fernandes, A. B., Alves da Silva, J., Almeida, J., Cui, G., Gerfen, C. R., Costa, R. M., & Oliveira-Maia, A. (2020). Postingestive modulation of food seeking depends on vagus-mediated dopamine neuron activity. Neuron. https://doi.org/10.1016/j.neuron.2020.03.009
2-year Impact Factor: 17.173|2020
Times cited: 57|2024-02-13
Indexed document: Yes
Quartile: Q1
Keywords: Postingestive / Ventral Tegmental Area / Dopamine / Feeding behavior / Food seeking / Nutrient sensing / Vagus nerve

DocumentPsychometric properties of the Portuguese version of the Yale Food Addiction Scale2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.09
Location: Arquivo PCA - Pasta 14/2010
Title:
Psychometric properties of the Portuguese version of the Yale Food Addiction Scale
Publication year: 2017
URL:
https://link.springer.com/article/10.1007/s40519-016-0349-6
Abstract/Results: ABSTRACT:
PURPOSE:
Rising rates of obesity have been recently associated to the novel concept of food addiction (FA). The Yale Food Addiction Scale (YFAS) is the most widely used measure for examining FA (1) and analysis of its reliability and validity is expected to facilitate empirical research on the construct. Here, we tested the psychometric properties of a Portuguese version of the YFAS (P-YFAS), establishing its factor structure, reliability and construct validity.
METHODS:
Data were obtained from 468 Portuguese individuals, 278 sampled from non-clinical populations, and 190 among obese candidates for weight-loss surgery. A battery of self-report measures of eating behavior was applied.
RESULTS:
Confirmatory factor analysis verified a one-factor structure with acceptable fit, with item analysis suggesting the need to eliminate item 24 from the P-YFAS. Internal consistency (KR-20 = .82) and test-retest stability were adequate. Correlation analyses supported convergent and divergent validity of the P-YFAS, particularly in the clinical sample. Both FA symptom count and diagnosis, according to the P-YFAS, adequately discriminated between samples, with classification of FA met by 2.5 and 25.8% of the participants in the non-clinical and clinical samples, respectively.
CONCLUSIONS:
These findings reinforce the use of P-YFAS in non-clinical and clinical populations. Future directions for extending YFAS validation are discussed.
Accessibility: Document exists in file
Language:
eng
Author:
Torres, S.
Secondary author(s):
Camacho, M. , Costa, P. , Ribeiro, G. , Santos, O. , Vieira, F. M., Brandão, I. , Sampaio, D. , Oliveira-Maia, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Torres, S., Camacho, M., Costa, P., Ribeiro, G., Santos, O., Vieira, F. M., ... Oliveira-Maia, A. (2017). Psychometric properties of the Portuguese version of the Yale Food Addiction Scale. Eating and Weight Disorders, 22, 259–267. https://doi.org/10.1007/s40519-016-0349-6
2-year Impact Factor: 2.154|2017
Times cited: 25|2024-02-08
Indexed document: Yes
Quartile: Q3
Keywords: Food addiction / Obesity / Psychometrics / Reward

Psychometric properties of the Portuguese version of the Yale Food Addiction Scale

Psychometric properties of the Portuguese version of the Yale Food Addiction Scale

DocumentReward-related gustatory and psychometric predictors of weight loss following bariatric surgery: a multicenter cohort study2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.10
Location: Arquivo PCA - Pasta 14/2010
Title:
Reward-related gustatory and psychometric predictors of weight loss following bariatric surgery: a multicenter cohort study
Publication year: 2021
URL:
https://academic.oup.com/ajcn/advance-article/doi/10.1093/ajcn/nqaa349/6131431
Abstract/Results: ABSTRACT:
BAKGROUND
Reward sensitivity has been proposed as a potential mediator of outcomes for bariatric surgery.
OBJECTIVES
We aimed to determine whether gustatory and psychometric measures of reward-related feeding are predictors of bariatric-induced weight loss.
METHODS
A multicenter longitudinal cohort study was conducted in patients scheduled for bariatric surgery (surgical group), assessed at baseline and 2 follow-up assessments. Predictions of % weight loss from baseline (%WL) according to baseline gustatory measures, including intensity and pleasantness ratings of sweet and other tastants, and psychometric measures of reward-related feeding behavior, including hedonic hunger scores, were assessed with multivariable linear regression. Exploratory analyses were conducted to test for associations between %WL and changes in gustatory and psychophysical measures, as well as for comparisons with data from patients on the surgery waiting list (control group).
RESULTS
We included 212 patients, of whom 96 in the surgical group and 50 in the control group were prospectively assessed. The groups were similar at baseline and, as expected, bariatric surgery resulted in higher %WL (BTreatment-Time = 2.4; 95% CI: 2.1–2.8; P < 0.0001). While variation in gustatory measures did not differ between groups, in the surgery group baseline sweet intensity predicted %WL at the primary endpoint (11 to 18 months postoperatively; ß = 0.2; B = 0.2, 95% CI: 0.02 to 0.3; P = 0.02), as did hedonic hunger scores (ß = -0.2; B = -2.0, 95% CI: -3.8 to -0.3; P = 0.02). Furthermore, at this endpoint, postsurgical reduction of sweet taste intensity and acceptance of sweet foods were associated with %WL (ß = -0.3; B = -3.5, 95% CI: -5.8 to -1.3; P = 0.003, and ß = -0.2; B = -4.7, 95% CI: -8.5 to -0.8; P = 0.02, respectively). The use of sweet intensity as a predictor of weight change was confirmed in another bariatric cohort.
CONCLUSIONS
Sweet intensity ratings and hedonic hunger scores predict %WL after surgery. The variability of sweet intensity ratings is also associated with %WL, further suggesting they may reflect physiological processes that are variably modulated by bariatric surgery, influencing clinical outcomes.
Accessibility: Document exists in file
Language:
eng
Author:
Ribeiro, G.
Secondary author(s):
Camacho, M., Fernandes, A. B., Cotovio, G., Torres, S., Oliveira-Maia, A.
Document type:
Article
Number of reproductions:
1
Reference:
Ribeiro, G., Camacho, M., Fernandes, A. B., Cotovio, G., Torres, S., Oliveira-Maia, A., & Food Reward in Bariatric Surgery Portuguese Study Group (2021). Reward-related gustatory and psychometric predictors of weight loss following bariatric surgery: a multicenter cohort study. The American Journal of Clinical Nutrition, nqaa349. https://doi.org/10.1093/ajcn/nqaa349
2-year Impact Factor: 7.045|2020
Impact factor notes: Impact factor not available yet for 2021
Times cited: 11|2024-02-14
Indexed document: Yes
Quartile: Q1
Keywords: Food reward / Feeding behavior / Sweet taste / Gustation / Psychometry / Weight loss / Bariatric surger

Reward-related gustatory and psychometric predictors of weight loss following bariatric surgery: a multicenter cohort study

Reward-related gustatory and psychometric predictors of weight loss following bariatric surgery: a multicenter cohort study

DocumentSweet taste and obesity2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.11
Location: Arquivo PCA - Pasta 14/2010
Title:
Sweet taste and obesity
Publication year: 2021
URL:
https://www.sciencedirect.com/science/article/pii/S0953620521000236
Abstract/Results: ABSTRACT:
For more than 50 years, there has been evidence for greater consumption of sweet- foods in overweight humans and animals, relative to those that have a normal weight. Furthermore, it has long been suggested that energy deficit resulting from dieting, while moving the individual from a higher weight set point, would result in heightened susceptibility to palatable tastants, namely to sweet tastants. This was the motivation behind the first studies comparing sweet taste perception between individuals with obesity and those of a normal weight. These studies, using direct measures of taste, have been characterized by significant methodological heterogeneity, contributing towards variability in results and conclusions. Nevertheless, some of these findings have been used to support the theory that patients with obesity have decreased taste perception, particularly for sweet tastants. A similar hypothesis has been proposed regarding evidence for reduced brain dopamine receptors in obesity and, in both cases, it is proposed that increased food consumption, and associated weight gain, result from the need to increase sensory and brain stimulation. However, the available literature is not conclusive on the association between obesity and reduced sweet taste perception, with both negative and contradictory findings in comparisons between individuals with obesity and normal weight control subjects, as well as within-subject comparisons before and after bariatric surgery. Nevertheless, following either Roux-en-Y gastric bypass or sleeve gastrectomy, there is evidence of changes in taste perception, particularly for reward-related measures of sweet tastants, that should be further tested and confirmed in large samples, using consensual methodology.
Accessibility: Document exists in file
Language:
eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Ribeiro, G.
Document type:
Article
Number of reproductions:
1
Percentiles:
5
Reference:
Oliveira-Maia, A. J., & Ribeiro, G. (2021). Sweet taste and obesity. European Journal of Internal Medicine. https://doi.org/10.1016/j.ejim.2021.01.023
2-year Impact Factor: 7.749|2021
Times cited: 12|2024-02-14
Indexed document: Yes
Quartile: Q1
Keywords: Obesity / Bariatric surgery / Taste perception / Psychophysics / Reward-related feeding behavior

Sweet taste and obesity

Sweet taste and obesity

DocumentEnhanced sweet taste perception in obesity: Joint analysis of gustatory data from multiple studies2022

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2010
Location: Arquivo PCA - Pastas 1 a 23
Title:
2010 Grants
Start date: 2011-01

Reference code: PT/FB/BL-2010-176
Location: Arquivo PCA - Pasta 14/2010
Title:
176 - Dopaminergic regulation of dietary learning in humans and rodents
Duration: 2011-07 - 2014-07
Researcher(s):
Albino Jorge Carvalho de Sousa Oliveira Maia, Rui M. Costa
Institution(s): Champalimaud Foundation, Lisbon (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress report
Language: eng
Author:
Oliveira-Maia, A. J.
Secondary author(s):
Costa, R. M.
Number of reproductions:
1
Keywords:
Psychophysiology / Cognitive processes / Learning / Biopsychological problems / Diseases/Injuries / Obesity / Brain structure and function

Reference code: PT/FB/BL-2010-176.12
Location: BF-GMS
Title:
Enhanced sweet taste perception in obesity: Joint analysis of gustatory data from multiple studies
Publication year: 2022
URL:
https://www.frontiersin.org/articles/10.3389/fnut.2022.1028261/full
Abstract/Results: ABSTRACT:
INTRODUCTION:
While sweet taste perception is a potential determinant of feeding behavior in obesity, the supporting evidence is inconsistent and is typically associated with methodological limitations. Notably, possible associations between sweet taste perception and measures of food reward remain undetermined.
MATERIALS AND METHODS:
We conducted a cross-sectional analysis comparing 246 individuals with severe obesity and 174 healthy volunteers using a validated method for taste perception assessment. We included gustatory variables, namely intensity and pleasantness ratings of sour, salt, sweet, and bitter tastants, and taste thresholds assessed by electrogustometry. Reward-related feeding behavior, including hedonic hunger, food addiction, feeding behavior traits, and acceptance of foods and alcohol, was evaluated using self-rated scales for comparison with gustatory measures.
RESULTS:
In logistic regressions adjusted for age, gender, educational level, and research center, we found that a greater likelihood of belonging to the obesity group was associated with higher sweet intensity ratings (OR = 1.4, P = 0.01), hedonic hunger, food addiction symptoms, restrained and emotional eating (1.7 < OR = 4.6, all P = 0.001), and lower alcohol acceptance (OR = 0.6, P = 0.0002). Using principal component analysis, we found that while hedonic hunger, food addiction, and emotional eating were strongly interrelated, they were not associated with sweet intensity perception that, in turn, had a closer relationship with alcohol acceptance and restrained eating.
CONCLUSIONS:
We found that individuals with obesity report higher sweet taste intensity ratings than healthy controls. Furthermore, while psychological measures of reward-related feeding behavior assess a common construct, sweet intensity perception may represent a different obesity-related dimension.
Accessibility: Document exists in file
Language:
eng
Author:
Ribeiro, G.
Secondary author(s):
Torres, S., Fernandes, A. B., Camacho, M., Branco, T. L, Martins, S. S., Raimundo, A., Oliveira-Maia, A. J., Food Reward in Bariatric Surgery Portuguese Study Group
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Ribeiro, G., Torres, S., Fernandes, A. B., Camacho, M., Branco, T. L., Martins, S. S., Raimundo, A., Oliveira-Maia, A. J., & Food Reward in Bariatric Surgery Portuguese Study Group (2022). Enhanced sweet taste perception in obesity: Joint analysis of gustatory data from multiple studies. Frontiers in Nutrition, 9, 1028261. https://doi.org/10.3389/fnut.2022.1028261
2-year Impact Factor: 5.000|2022
Times cited: 3|2024-02-15
Indexed document: Yes
Quartile: Q2
Keywords: Food reward / Gustation / Hedonic hunger / Obesity / Reward-related feeding behavior / Sweet taste / Taste perception

Enhanced sweet taste perception in obesity: Joint analysis of gustatory data from multiple studies

Enhanced sweet taste perception in obesity: Joint analysis of gustatory data from multiple studies