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File021 - The depersonalized brain: Psychophysiological correlates of cortical hyperexcitability associated with signs of depersonalization, derealization and dissociation, in non-clinical samples2013-062015-09

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-021
Location: Arquivo PCA - Pasta 8/2012
Title:
021 - The depersonalized brain: Psychophysiological correlates of cortical hyperexcitability associated with signs of depersonalization, derealization and dissociation, in non-clinical samples
Duration: 2013-06 - 2015-09
Researcher(s):
Jason John Braithwaite
Institution(s): Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Language: eng
Author:
Braithwaite, J. J.
Number of reproductions:
3
Keywords:
Psychophysiology and Parapsychology / Biopsychological problems / Mental health / Dissociative disorders / Anomalous cognition/experiences

DocumentNeuroscience and anomalous experience: Cortical hyperexcitability and the out-of-body experience2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-021
Location: Arquivo PCA - Pasta 8/2012
Title:
021 - The depersonalized brain: Psychophysiological correlates of cortical hyperexcitability associated with signs of depersonalization, derealization and dissociation, in non-clinical samples
Duration: 2013-06 - 2015-09
Researcher(s):
Jason John Braithwaite
Institution(s): Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Language: eng
Author:
Braithwaite, J. J.
Number of reproductions:
3
Keywords:
Psychophysiology and Parapsychology / Biopsychological problems / Mental health / Dissociative disorders / Anomalous cognition/experiences

Reference code: PT/FB/BL-2012-021.02
Location: Arquivo PCA - Pasta 8/2012
Title:
Neuroscience and anomalous experience: Cortical hyperexcitability and the out-of-body experience
Publication year: 2014
URL:
http://abstracts.bps.org.uk/index.cfm?&ResultsType=Abstracts&ResultSet_ID=10970&FormDisplayMode=view&frmShowSelected=true&localAction=details
Abstract/Results: ABSTRACT:
OBJECTIVES:
Striped patterns (i.e. gratings) with a spatial frequency of three cycles-per-degree of visual angle are known to produce visual discomfort, induce phantom visual distortions and somatic sensations in susceptible observers. These phenomena have been termed ‘pattern-glare’ and are thought to reflect increased degrees of cortical hyperexcitability and be associated with visual hallucinations/aura. The present objective was to examine these signs of cortical hyperexcitability in non-clinical individuals predisposed to out-of-body experiences (OBEs).
DESIGN:
A within-subjects design was used. Participants completed questionnaire measures indexing their predisposition to specific anomalous perceptions (and the existence of OBEs) and then took part a pattern-glare task for a measure of cortical hyperexcitability.
METHODS:
A random sample of 50 non-clinical university undergraduates was recruited. A computer-based pattern-glare experiment, where participants viewed gratings of different spatial frequencies, was devised to examine degrees of cortical hyperexcitability in non-clinical hallucinators and control participants. Data were analysed via standard parametric and non-parametric procedures.
RESULTS:
Increased signs of cortical hyperexcitability (signified by increased ratings of visual irritability and increased numbers of phantom visual/somatic distortions from viewing certain striped gratings) significantly correlated with the incidence of OBEs and scores from independent questionnaire measures of anomalous perceptions.
CONCLUSIONS:
Pattern-glare tasks are sensitive to underlying cortical factors implicated in some somatic distortions and body-based hallucinations like the OBE. As a consequence, these tasks show considerable promise in their objective utility to identify neurocognitive factors underlying positive hallucinatory symptomology across a range of hallucinatory-prone non-clinical, neurological and clinical groups (e.g. Depersonalisation, Schizophrenia/Schizotypy, Dissociative disorders, Psychoses).
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Takahashi, C.
Secondary author(s):
Braithwaite, J. J.
Document type:
Online abstract
Number of reproductions:
3
Reference:
Takahashi, C., & Braithwaite, J. J. (2014, May). Neuroscience and anomalous experience: Cortical hyperexcitability and the out-of-body experience. Paper presented at the Annual conference of the British Psychological Society, Birmingham, UK. Abstract retrieved from http://abstracts.bps.org.uk/index.cfm?&ResultsType=Abstracts&ResultSet_ID=10970&FormDisplayMode=view&frmShowSelected=true&localAction=details
Indexed document: No
Keywords: Out-of-body experience (OBE) / Cortical hyperexcitability / Pattern-glare

Neuroscience and anomalous experience: Cortical hyperexcitability and the out-of-body experience

Neuroscience and anomalous experience: Cortical hyperexcitability and the out-of-body experience

DocumentFinal report - The depersonalized brain: Psychophysiological correlates of cortical hyperexcitability associated with signs of depersonalization, derealization and dissociation, in non-clinical samples2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-021
Location: Arquivo PCA - Pasta 8/2012
Title:
021 - The depersonalized brain: Psychophysiological correlates of cortical hyperexcitability associated with signs of depersonalization, derealization and dissociation, in non-clinical samples
Duration: 2013-06 - 2015-09
Researcher(s):
Jason John Braithwaite
Institution(s): Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Language: eng
Author:
Braithwaite, J. J.
Number of reproductions:
3
Keywords:
Psychophysiology and Parapsychology / Biopsychological problems / Mental health / Dissociative disorders / Anomalous cognition/experiences

Reference code: PT/FB/BL-2012-021.01
Location: Arquivo PCA - Pasta 8/2012
Title:
Final report - The depersonalized brain: Psychophysiological correlates of cortical hyperexcitability associated with signs of depersonalization, derealization and dissociation, in non-clinical samples
Publication year: 2015
URL:
https://www.bial.com/imagem/Bolsa2112_07102015.pdf
Abstract/Results: ABSTRACT:
BACKGROUND
This study explored the role of cortical hyperexcitability underlying the aberrant perceptions reported by those predisposed to sub-clinical levels of dissociative, depersonalization/ derealization experiences. The anomalous perceptions experienced in these conditions range for perceptual distortions in relation to one’s own body, to an altered experience of ones surroundings - though their neurocognitive underpinnings remain unclear.
METHOD
Participants were all screened on a variety of questionnaire measures that sought to quantify predisposition to anomalous perceptions. A revised version of the pattern-glare task was devised to examine the degree of visual distortions experienced from viewing irritable gratings. Interactions between perceptual (associated visual distortions) and emotional (facial EMG reactions) factors were explored to provide an objective psychophysiological index of both perceptual and emotional suppression as concomitants of dissociative states in the non-clinical population.
RESULTS
Those showing a predisposition to anomalous dissociative experiences reported significantly more perceptual distortions from viewing the gratings. There were no effects from psychophysiological recordings from emotional facial regions.
CONCLUSION
Cortical hyperexcitability may be one factor contributing to the anomalous perceptions reported by some experiencing dissociative conscious experiences. These effects may be more 'perceptual' than 'emotional'.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Braithwaite, J. J.
Document type:
Final report
Number of reproductions:
3
Indexed document:
No
Keywords: Dissociation / Hallucination / Aberrant perceptions / Depersonalization / Cortical hyperexcitability

DocumentStimulating the aberrant brain: Evidence for increased cortical hyperexcitability from a transcranial direct current stimulation (tDCS) study of individuals predisposed to anomalous perceptions2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-021
Location: Arquivo PCA - Pasta 8/2012
Title:
021 - The depersonalized brain: Psychophysiological correlates of cortical hyperexcitability associated with signs of depersonalization, derealization and dissociation, in non-clinical samples
Duration: 2013-06 - 2015-09
Researcher(s):
Jason John Braithwaite
Institution(s): Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Language: eng
Author:
Braithwaite, J. J.
Number of reproductions:
3
Keywords:
Psychophysiology and Parapsychology / Biopsychological problems / Mental health / Dissociative disorders / Anomalous cognition/experiences

Reference code: PT/FB/BL-2012-021.03
Location: Arquivo PCA - Pasta 8/2012
Title:
Stimulating the aberrant brain: Evidence for increased cortical hyperexcitability from a transcranial direct current stimulation (tDCS) study of individuals predisposed to anomalous perceptions
Publication year: 2015
URL:
http://www.sciencedirect.com/science/article/pii/S0010945215001227
Abstract/Results: ABSTRACT:
Findings from neurological and clinical groups have shown that increased predisposition to anomalous experience/aura reflects an elevation in aberrant neural processes in the brain. However, studies of anomalous experiences in non-clinical/non-neurological groups are less clear on this matter and are more typically confined to subjective questionnaire measures alone. The current investigation, the first to our knowledge, carried out a transcranial Direct Current Stimulation (tDCS) study of cortical hyperexcitability, and its association with anomalous experience in non-clinical/non-neurological groups. Sixty participants completed; (i) both excitatory (anodal) and inhibitory (cathodal) brain stimulation conditions of the visual cortex; (ii) a computerised pattern-glare task, where observers reported phantom visual distortions from viewing highly irritable visual patterns (a metric of cortical hyperexcitability), and; (iii) questionnaire measures of predisposition to anomalous perceptions. There were no reliable signs of cortical hyperexcitability (via pattern-glare tasks) when collapsed across the whole sample. However, a significant positive correlation between predisposition to anomalous experience and elevated signs of cortical hyperexcitability was observed. Crucially, there was a significant negative correlation between tDCS stimulatory conditions. A visual cortex that reacted more strongly to excitatory stimulation, responded less well to inhibitory suppression, and this pattern was related to predisposition to anomalous perceptions. Both findings are consistent with the presence of a hyperexcitable cortex. Collectively the present findings provide objective evidence that the brains of individuals predisposed to anomalous experiences/hallucinations can be hyperexcitable – even in the non-clinical/non-neurological population. These data are consistent with continuum models of anomalous experience and have important implications for contemporary theories of aberrations in self-consciousness.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Author:
Braithwaite, J. J.
Secondary author(s):
Mevorach, C., Takahashi, C.
Document type:
Article
Number of reproductions:
3
Percentiles:
6|2022-03-19
Reference:
Braithwaite, J. J., Mevorach, C., & Takahashi, C. (2015). Stimulating the aberrant brain: Evidence for increased cortical hyperexcitability from a transcranial direct current stimulation (tDCS) study of individuals predisposed to anomalous perceptions. Cortex, 69, 1–13. doi: 10.1016/j.cortex.2015.03.023
2-year Impact Factor: 4.314|2015
Times cited: 11|2022-05-22
Indexed document: Yes
Quartile: Q1
Keywords: Cortical hyperexcitability / TDCS / Hallucinations / Brain stimulation / Pattern-glare

DocumentThe Cortical Hyperexcitability Index (CHi): a new measure for quantifying correlates of visually driven cortical hyperexcitability2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-021
Location: Arquivo PCA - Pasta 8/2012
Title:
021 - The depersonalized brain: Psychophysiological correlates of cortical hyperexcitability associated with signs of depersonalization, derealization and dissociation, in non-clinical samples
Duration: 2013-06 - 2015-09
Researcher(s):
Jason John Braithwaite
Institution(s): Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Language: eng
Author:
Braithwaite, J. J.
Number of reproductions:
3
Keywords:
Psychophysiology and Parapsychology / Biopsychological problems / Mental health / Dissociative disorders / Anomalous cognition/experiences

Reference code: PT/FB/BL-2012-021.04
Location: Arquivo PCA - Pasta 8/2012
Title:
The Cortical Hyperexcitability Index (CHi): a new measure for quantifying correlates of visually driven cortical hyperexcitability
Publication year: 2015
URL:
http://www.tandfonline.com/doi/abs/10.1080/13546805.2015.1040152?journalCode=pcnp20#.Vfw6eHlREeE
Abstract/Results: ABSTRACT:
INTRODUCTION:
Aberrations of visual experience, including visual hallucinations and visual distortions, are known to be associated with increased cortical hyperexcitability. As a consequence, the presence, intensity and frequency of certain experiences may
well be indicative of an underlying increase in cortical hyperexcitability.
METHOODS:
The current study presents a new proxy measure of cortical hyperexcitability, the Cortical Hyperexcitability Index (CHi). Two hundred and fifty healthy participants completed the CHi with the results subjected to exploratory factor analysis (EFA).
RESULTS:
The EFA revealed a three-factor model as the most parsimonious solution. The three factors were defined as: (1) heightened visual sensitivity and discomfort; (2) negative aura-type visual aberrations; and (3) positive aura-type visual aberrations. The identification of three factors suggests that multiple mechanisms underlie the notion of cortical hyperexcitability, providing researchers with new and greater precision in delineating these underlying features.
CONCLUSIONS:
The factorial structure of the CHi and the increased precision could aid the interpretation of findings from neuroscientific (i.e., brain imaging/stimulation) examinations of cortical processes underlying aberrant perceptions across a host of
clinical, neurological and pathological conditions. As a consequence, the CHi is a useful and comprehensive proxy measure of cortical hyperexcitability with considerable scientific and clinical utility.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Braithwaite, J. J.
Secondary author(s):
Marchant, R., Takahashi, C., Dewe, H., Watson, D.
Document type:
Article
Number of reproductions:
3
Percentiles:
7|2022-03-19
Reference:
Braithwaite, J. J., Marchant, R., Takahashi, C., Dewe, H., & Watson, D. (2015). The Cortical Hyperexcitability Index (CHi): a new measure for quantifying correlates of visually driven cortical hyperexcitability. Cognitive Neuropsychiatry, 20(4), 330-348. doi: 10.1080/13546805.2015.1040152
2-year Impact Factor: 1.924|2015
Times cited: 5|2022-05-22
Indexed document: Yes
Quartile: Q3
Keywords: Cortical hyperexcitability / Hallucinations / Aberrant experience / Consciousness

DocumentStimulating the aberrant brain: Predisposition to anomalous visual distortions reflects increased cortical hyperexcitability in those prone to Hallucinations: Evidence from a tDCS brain stimulation study2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-021
Location: Arquivo PCA - Pasta 8/2012
Title:
021 - The depersonalized brain: Psychophysiological correlates of cortical hyperexcitability associated with signs of depersonalization, derealization and dissociation, in non-clinical samples
Duration: 2013-06 - 2015-09
Researcher(s):
Jason John Braithwaite
Institution(s): Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Language: eng
Author:
Braithwaite, J. J.
Number of reproductions:
3
Keywords:
Psychophysiology and Parapsychology / Biopsychological problems / Mental health / Dissociative disorders / Anomalous cognition/experiences

Reference code: PT/FB/BL-2012-021.05
Location: Arquivo PCA - Pasta 8/2012
Title:
Stimulating the aberrant brain: Predisposition to anomalous visual distortions reflects increased cortical hyperexcitability in those prone to Hallucinations: Evidence from a tDCS brain stimulation study
Publication year: 2015
URL:
http://easychair.org/smart-program/ECVP2015/2015-08-27.html#talk:10329
Abstract/Results: ABSTRACT:
Clinical and neurological research has suggested that increased predisposition to anomalous perceptual experience can result from increases in cortical hyperexcitability. However, such studies are often based on subjective questionnaire measures alone. The present study examined the role of cortical hyperexcitability in healthy individuals predisposed to anomalous hallucinatory visual experiences by manipulating the level of excitability in the visual cortex via transcranial direct current stimulation (tDCS). Sixty participants completed questionnaire measures indexing their predispositions to anomalous perceptions. They also took part in a computer based pattern-glare task (view irritable gratings) across three separate tDCS sessions (sham/anodal/cathodal) applied over the visual cortex. Participants reported the number of phantom visual and somatic distortions experienced during the viewing these highly irritable gratings. Those predisposed to anomalous experiences, reported more visual distortions as a result of viewing the grating stimuli even under sham conditions. In addition, these individuals responded more strongly to excitatory stimulation of the visual cortex (reporting more visual distortions as a result of such stimulation), yet more weakly to inhibitory stimulation of the same brain regions. Collectively, these findings are consistent with a hyperexcitable cortex being associated with proneness to report more visual distortions and hallucinations even in non-clinical samples.
Accessibility: Document does exist in file
Language:
eng
Author:
Takahashi, C.
Secondary author(s):
Braithwaite, J. J.
Document type:
Online abstract
Number of reproductions:
3
Reference:
Takahashi, C. & Braithwaite, J. J. (2015, August). Stimulating the aberrant brain: Predisposition to anomalous visual distortions reflects increased cortical hyperexcitability in those prone to Hallucinations: Evidence from a tDCS brain stimulation study. Poster presented at The European Conference of Visual Perception (ECVP), Liverpool, UK. Abstract retrieved from http://easychair.org/smart-program/ECVP2015/2015-08-27.html#talk:10329
Indexed document: No
Keywords: Hallucinations / Transcranial direct current stimulation (TDCS) / Cortical hyperexcitability

DocumentThe Cortical Hyperexcitability Index (CHi): A new measure for quantifying correlates of visually-driven cortical hyperexcitability2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-021
Location: Arquivo PCA - Pasta 8/2012
Title:
021 - The depersonalized brain: Psychophysiological correlates of cortical hyperexcitability associated with signs of depersonalization, derealization and dissociation, in non-clinical samples
Duration: 2013-06 - 2015-09
Researcher(s):
Jason John Braithwaite
Institution(s): Behavioural Brain Sciences Centre, School of Psychology, University of Birmingham (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Language: eng
Author:
Braithwaite, J. J.
Number of reproductions:
3
Keywords:
Psychophysiology and Parapsychology / Biopsychological problems / Mental health / Dissociative disorders / Anomalous cognition/experiences

Reference code: PT/FB/BL-2012-021.06
Location: Arquivo PCA - Pasta 8/2012
Title:
The Cortical Hyperexcitability Index (CHi): A new measure for quantifying correlates of visually-driven cortical hyperexcitability
Publication year: 2015
URL:
http://www.eps.ac.uk/images/Lincoln%20meeting%20programme%20July%202015.pdf
Abstract/Results: ABSTRACT:
Aberrations of visual experience (visual distortions / hallucinations) are known to be associated with increased cortical hyperexcitability. Therefore, the presence, intensity and frequency of certain experiences may well be indicative of an increase in cortical hyperexcitability. The current study presents a new 27-item proxy measure of cortical hyperexcitability: the Cortical Hyperexcitability index (CHi). Two-hundred and fifty healthy participants completed the CHi with the results subjected to Exploratory Factor Analysis (EFA) and Parallel Analysis. The EFA revealed a 3-factor model as the most parsimonious solution. The 3-factors were defined as; (i) heightened visual sensitivity and discomfort; (ii) negative aura-type visual aberrations; and, (iii) positive aura-type visual aberrations. The identification of the 3-factors suggest that multiple mechanisms underlie the notion of cortical hyperexcitability, proving researchers with new and greater precision in delineating the underlying mechanisms. The factor structure of the CHi, and the increased precision could aid the interpretation of findings from neuroscientific (i.e., neuroimaging / brain stimulation) examinations of cortical processes predisposing individuals to aberrant perceptions across a legion of clinical, neurological, and pathological conditions. As a consequence, the CHi provides a useful and comprehensive proxy measure of cortical hyperexctability and has considerable scientific and clinical utility.
Accessibility: Document does not exist in file
Language:
eng
Author:
Takahashi, C.
Secondary author(s):
Marchant, R., Dewe, H., Watson, D., Braithwaite, J. J.
Document type:
Abstract book
Number of reproductions:
3
Reference:
Takahashi, C., Marchant, R., Dewe, H., Watson, D., & Braithwaite, J. J. (2015). The Cortical Hyperexcitability Index (CHi): A new measure for quantifying correlates of visually-driven cortical hyperexcitability. Abstract Book of Experimental Psychology Society (EPS), Lincoln meeting, UK (p. 44).
Indexed document: No
Keywords: Hallucinations / Cortical hyperexcitability

The Cortical Hyperexcitability Index (CHi): A new measure for quantifying correlates of visually-driven cortical hyperexcitability

The Cortical Hyperexcitability Index (CHi): A new measure for quantifying correlates of visually-driven cortical hyperexcitability