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File119 - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings2013-062016-10

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-119
Location: Arquivo PCA - Pastas 20/2012
Title:
119 - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings
Duration: 2013-06 - 2016-10
Researcher(s):
Bryan Strange, Javier J. Gonzalez-Rosa, Juan A. Barcia, Stephan Moratti, Raffael Kaplan, Marijn Kroe
Institution(s): Laboratory for Clinical Neuroscience, Centre for Biomedical Technology (CTB), Technology University of Madrid (UPM) and Fundación para la Investigación Biomédica del Hospital Clínico San Carlos - Universidad Complutense de Madrid. Instituto de Investigación Sanitario IdISSC (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
2 posters
Language: eng
Author:
Strange, B.
Secondary author(s):
Gonzalez-Rosa, J., Barcia, J., Moratti, S., Kaplan, R., Kroe, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Anxiety disorders / Brain structure and function / Cognitive processes / Intervention
DocumentCaracterizing the spiking properties of human nucleus accumbens neurons and their responses to novelty2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-119
Location: Arquivo PCA - Pastas 20/2012
Title:
119 - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings
Duration: 2013-06 - 2016-10
Researcher(s):
Bryan Strange, Javier J. Gonzalez-Rosa, Juan A. Barcia, Stephan Moratti, Raffael Kaplan, Marijn Kroe
Institution(s): Laboratory for Clinical Neuroscience, Centre for Biomedical Technology (CTB), Technology University of Madrid (UPM) and Fundación para la Investigación Biomédica del Hospital Clínico San Carlos - Universidad Complutense de Madrid. Instituto de Investigación Sanitario IdISSC (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
2 posters
Language: eng
Author:
Strange, B.
Secondary author(s):
Gonzalez-Rosa, J., Barcia, J., Moratti, S., Kaplan, R., Kroe, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Anxiety disorders / Brain structure and function / Cognitive processes / Intervention

Reference code: PT/FB/BL-2012-119.02
Location: Arquivo PCA - Pastas 20/2012
Title:
Caracterizing the spiking properties of human nucleus accumbens neurons and their responses to novelty
Publication year: 2014
Accessibility:
Document exists in file
Language:
eng
Author:
Kroe, M.
Secondary author(s):
Lopez-Sosa, F., Avecillas, J., Acedo, V. M., Gonzalez-Hidalgo, M., Lopez-Ibor, J., Battaglia, F., Barcia, J., Strange, B.
Document type:
Unpublished document
Number of reproductions:
1
Reference:
Kroe, M., Lopez-Sosa, F., Avecillas, J., Acedo, V. M., Gonzalez-Hidalgo, M., Lopez-Ibor, J., Battaglia, F., Barcia, J., & Strange, B. (2014, June). Caracterizing the spiking properties of human nucleus accumbens neurons and their responses to novelty. Poster presented at the Organization for Human Brain Mapping, Hamburg, Germany.
Indexed document: No
Keywords: Novelty / Nucleus accumbens

Caracterizing the spiking properties of human nucleus accumbens neurons and their responses to novelty

Caracterizing the spiking properties of human nucleus accumbens neurons and their responses to novelty
DocumentMemory enhancement via deep brain stimulation of human nucleus accumbens2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-119
Location: Arquivo PCA - Pastas 20/2012
Title:
119 - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings
Duration: 2013-06 - 2016-10
Researcher(s):
Bryan Strange, Javier J. Gonzalez-Rosa, Juan A. Barcia, Stephan Moratti, Raffael Kaplan, Marijn Kroe
Institution(s): Laboratory for Clinical Neuroscience, Centre for Biomedical Technology (CTB), Technology University of Madrid (UPM) and Fundación para la Investigación Biomédica del Hospital Clínico San Carlos - Universidad Complutense de Madrid. Instituto de Investigación Sanitario IdISSC (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
2 posters
Language: eng
Author:
Strange, B.
Secondary author(s):
Gonzalez-Rosa, J., Barcia, J., Moratti, S., Kaplan, R., Kroe, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Anxiety disorders / Brain structure and function / Cognitive processes / Intervention

Reference code: PT/FB/BL-2012-119.03
Location: Arquivo PCA - Pastas 20/2012
Title:
Memory enhancement via deep brain stimulation of human nucleus accumbens
Publication year: 2014
Accessibility:
Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Galarza-Vallejo, A.
Secondary author(s):
Gonzalez-Rosa, J., Arza, R., Reneses, P., Barcia, J., Strange, B.
Document type:
Unpublished document
Number of reproductions:
1
Reference:
Galarza-Vallejo, A., Gonzalez-Rosa, J., Arza, R., Reneses, P., Barcia, J., & Strange, B. (2014, June). Memory enhancement via deep brain stimulation of human nucleus accumbens. Poster presented at the Organization for Human Brain Mapping, Hamburg, Germany.
Indexed document: No
Keywords: Episodic memory / Nucleus accumbens / Obsessive-compulsive disorders

Memory enhancement via deep brain stimulation of human nucleus accumbens

Memory enhancement via deep brain stimulation of human nucleus accumbens
DocumentDynamic risk control by human nucleus accumbens2014

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-119
Location: Arquivo PCA - Pastas 20/2012
Title:
119 - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings
Duration: 2013-06 - 2016-10
Researcher(s):
Bryan Strange, Javier J. Gonzalez-Rosa, Juan A. Barcia, Stephan Moratti, Raffael Kaplan, Marijn Kroe
Institution(s): Laboratory for Clinical Neuroscience, Centre for Biomedical Technology (CTB), Technology University of Madrid (UPM) and Fundación para la Investigación Biomédica del Hospital Clínico San Carlos - Universidad Complutense de Madrid. Instituto de Investigación Sanitario IdISSC (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
2 posters
Language: eng
Author:
Strange, B.
Secondary author(s):
Gonzalez-Rosa, J., Barcia, J., Moratti, S., Kaplan, R., Kroe, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Anxiety disorders / Brain structure and function / Cognitive processes / Intervention

Reference code: PT/FB/BL-2012-119.04
Location: Arquivo PCA - Pastas 20/2012
Title:
Dynamic risk control by human nucleus accumbens
Publication year: 2014
Accessibility:
Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Nachev, P.
Secondary author(s):
Lopez-Sosa, F., Gonzalez-Rosa, J., Rascon, F., Lopez-Ibor, J., Barcia, J., Strange, B.
Document type:
Unpublished document
Number of reproductions:
1
Reference:
Nachev, P., Lopez-Sosa, F., Gonzalez-Rosa, J., Rascon, F., Lopez-Ibor, J., Barcia, J., & Strange, B. (2014, June). Dynamic risk control by human nucleus accumbens. Poster presented at the Organization for Human Brain Mapping, Hamburg, Germany.
Indexed document: No
Keywords: Decision-making / Nucleus accumbens / Deep brain stimulation

Dynamic risk control by human nucleus accumbens

Dynamic risk control by human nucleus accumbens
DocumentDynamic risk control by human nucleus accumbens2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-119
Location: Arquivo PCA - Pastas 20/2012
Title:
119 - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings
Duration: 2013-06 - 2016-10
Researcher(s):
Bryan Strange, Javier J. Gonzalez-Rosa, Juan A. Barcia, Stephan Moratti, Raffael Kaplan, Marijn Kroe
Institution(s): Laboratory for Clinical Neuroscience, Centre for Biomedical Technology (CTB), Technology University of Madrid (UPM) and Fundación para la Investigación Biomédica del Hospital Clínico San Carlos - Universidad Complutense de Madrid. Instituto de Investigación Sanitario IdISSC (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
2 posters
Language: eng
Author:
Strange, B.
Secondary author(s):
Gonzalez-Rosa, J., Barcia, J., Moratti, S., Kaplan, R., Kroe, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Anxiety disorders / Brain structure and function / Cognitive processes / Intervention

Reference code: PT/FB/BL-2012-119.05
Location: Arquivo PCA - Pastas 20/2012
Title:
Dynamic risk control by human nucleus accumbens
Publication year: 2015
URL:
http://brain.oxfordjournals.org/content/early/2015/10/01/brain.awv285#ack-1
Abstract/Results: ABSTRACT:
Real-world decisions about reward often involve a complex counterbalance of risk and value. Although the nucleus accumbens has been implicated in the underlying neural substrate, its criticality to human behaviour remains an open question, best addressed with interventional methodology that probes the behavioural consequences of focal neural modulation. Combining a psychometric index of risky decision-making with transient electrical modulation of the nucleus accumbens, here we reveal profound, highly dynamic alteration of the relation between probability of reward and choice during therapeutic deep brain stimulation in four patients with treatment-resistant psychiatric disease. Short-lived phasic electrical stimulation of the region of the nucleus accumbens dynamically altered risk behaviour, transiently shifting the psychometric function towards more risky decisions only for the duration of stimulation. A critical, on-line role of human nucleus accumbens in dynamic risk control is thereby established.
Accessibility: Document exist in file
Language:
eng
Author:
Nachev, P.
Secondary author(s):
Lopez-Sosa, F., Gonzalez-Rosa, J., Galarza, A., Avecillas, J., Pineda-Pardo, J. A., Lopez-Ibor, J., Reneses, B., Barcia, J., Strange, B.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Nachev, P., Lopez-Sosa, F., Gonzalez-Rosa, J., Galarza, A., Avecillas, J., ..., Strange, B. (2015). Dynamic risk control by human nucleus accumbens. Brain, 138(12), 3496-3502. https://doi.org/10.1093/brain/awv285
2-year Impact Factor: 10.103|2015
Times cited: 10|2024-02-07
Indexed document: Yes
Quartile: Q1
Keywords: Nucleus accumbens / Risk / Reward / Decision-making / Subcortical electrical stimulation

Dynamic risk control by human nucleus accumbens

Dynamic risk control by human nucleus accumbens
DocumentFinal report - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-119
Location: Arquivo PCA - Pastas 20/2012
Title:
119 - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings
Duration: 2013-06 - 2016-10
Researcher(s):
Bryan Strange, Javier J. Gonzalez-Rosa, Juan A. Barcia, Stephan Moratti, Raffael Kaplan, Marijn Kroe
Institution(s): Laboratory for Clinical Neuroscience, Centre for Biomedical Technology (CTB), Technology University of Madrid (UPM) and Fundación para la Investigación Biomédica del Hospital Clínico San Carlos - Universidad Complutense de Madrid. Instituto de Investigación Sanitario IdISSC (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
2 posters
Language: eng
Author:
Strange, B.
Secondary author(s):
Gonzalez-Rosa, J., Barcia, J., Moratti, S., Kaplan, R., Kroe, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Anxiety disorders / Brain structure and function / Cognitive processes / Intervention

Reference code: PT/FB/BL-2012-119.01
Location: Arquivo PCA - Pastas 20/2012
Title:
Final report - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings
Publication year: 2016
Abstract/Results:
ABSTRACT:
BACKGROUND
Deep-brain stimulation (DBS) is being increasingly used to treat medication resistant neurological and psychiatric diseases. However, the cognitive effects of DBS are not well understood.
AIM OF THE STUDY
To determine the effects of DBS to the human nucleus accumbens (NAc) on cognitive function.
METHOD
During the project period, 11 patients (10 with obsessive-compulsive disorder and 1 with major depression) underwent bilateral implantation of DBS electrodes. Intra-operatively, we recorded single-unit activity from the NAc during an auditory oddball task. Post-operatively, patients performed 3 behavioural tasks, with NAc DBS (130Hz, 3.5V, 60µs pulse-width) applied at 2 intervals during the task (On/Off design). In the third study, we simultaneously acquired scalp electroencephalography (EEG) recordings.
RESULTS & CONCLUSIONS
Intra-operative recordings - Different forms of salience evoke a change in human NAc single neuron firing rate, at a latency ~200 ms. Risky decision-making - We found that NAc DBS disrupts the normal relation between probability of reward and choice in 4 patients, resulting in a shift towards more risk seeking behaviour. Memory encoding - In all 6 patients tested, we found that NAc DBS during encoding of images increases the probability that these images will be later recognised. The magnitude of this memory enhancement predicts memory improvement in a neuropsychological test of verbal memory after 2 months of chronic DBS. Target detection during sustained attention - In 6 patients tested with the AX-type continuous performance task (AX-CPT), NAc DBS evoked a reduction of total numbers of errors in the ON relative to OFF state. In the EEG, NAc DBS produced an increase in the distribution of sources generating the P3 potential during Go trials. NAc DBs has profound effects on cognitive function.
Accessibility: Deocument exists in file
Copyright/Reproduction:
By permission
Language:
eng
Notes:
Deep-brain stimulation, Intracranial recordings, Nucleus accumbens, Electroencephalogram (EEG)
Author: Strange, B.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Deep brain stimulation / Intracranial recordings / Nucleus accumbens / Electroencephalogram (EEG)
DocumentDeep-brain stimulation of human nucleus accumbens dynamically alters risky decision-making2015

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-119
Location: Arquivo PCA - Pastas 20/2012
Title:
119 - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings
Duration: 2013-06 - 2016-10
Researcher(s):
Bryan Strange, Javier J. Gonzalez-Rosa, Juan A. Barcia, Stephan Moratti, Raffael Kaplan, Marijn Kroe
Institution(s): Laboratory for Clinical Neuroscience, Centre for Biomedical Technology (CTB), Technology University of Madrid (UPM) and Fundación para la Investigación Biomédica del Hospital Clínico San Carlos - Universidad Complutense de Madrid. Instituto de Investigación Sanitario IdISSC (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
2 posters
Language: eng
Author:
Strange, B.
Secondary author(s):
Gonzalez-Rosa, J., Barcia, J., Moratti, S., Kaplan, R., Kroe, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Anxiety disorders / Brain structure and function / Cognitive processes / Intervention

Reference code: PT/FB/BL-2012-119.06
Location: Arquivo PCA - Pastas 20/2012
Title:
Deep-brain stimulation of human nucleus accumbens dynamically alters risky decision-making
Publication year: 2015
URL:
http://www.brainstimjrnl.com/article/S1935-861X(15)00671-3/abstract
Abstract/Results: ABSTRACT:
Activity in human nucleus accumbens (NAc) is known to covary with risk when choosing between uncertain rewards. Whether this activity is critical to human behaviour remains, however, an open question, best addressed with methodology that probes the behavioural consequences of focal functional disruption of the region. Here we combine a behavioural index of risky decision-making with dynamic disruption of the NAc during therapeutic deep brain stimulation (DBS) to determine the critical relation between the two.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Nachev, P.
Secondary author(s):
Lopez-Sosa, F., Gonzalez-Rosa, J., Avecillas, J., Lopez-Ibor, J., Barcia, J., Strange, B.
Document type:
Abstract
Number of reproductions:
1
Reference:
Nachev, P., Lopez-Sosa, F., Gonzalez-Rosa, J., Avecillas, J., Lopez-Ibor, J., Barcia, J., & Strange, B. (2015). Deep-brain stimulation of human nucleus accumbens dynamically alters risky decision-making. Brain stimulation, 8(2), 390. https://doi.org/10.1016/j.brs.2015.01.247
Indexed document: Yes
Keywords: Deep brain stimulation / Nucleus accumbens
DocumentA fast pathway for fear in human amygdala2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-119
Location: Arquivo PCA - Pastas 20/2012
Title:
119 - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings
Duration: 2013-06 - 2016-10
Researcher(s):
Bryan Strange, Javier J. Gonzalez-Rosa, Juan A. Barcia, Stephan Moratti, Raffael Kaplan, Marijn Kroe
Institution(s): Laboratory for Clinical Neuroscience, Centre for Biomedical Technology (CTB), Technology University of Madrid (UPM) and Fundación para la Investigación Biomédica del Hospital Clínico San Carlos - Universidad Complutense de Madrid. Instituto de Investigación Sanitario IdISSC (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
2 posters
Language: eng
Author:
Strange, B.
Secondary author(s):
Gonzalez-Rosa, J., Barcia, J., Moratti, S., Kaplan, R., Kroe, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Anxiety disorders / Brain structure and function / Cognitive processes / Intervention

Reference code: PT/FB/BL-2012-119.07
Location: Arquivo PCA - Pastas 20/2012
Title:
A fast pathway for fear in human amygdala
Publication year: 2016
URL:
http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.4324.html
Abstract/Results: ABSTRACT:
A fast, subcortical pathway to the amygdala is thought to have evolved to enable rapid detection of threat. This pathway’s existence is fundamental for understanding nonconscious emotional responses, but has been challenged as a result of a lack of evidence for short-latency fear-related responses in primate amygdala, including humans. We recorded human intracranial electrophysiological data and found fast amygdala responses, beginning 74-ms post-stimulus onset, to fearful, but not neutral or happy, facial expressions. These responses had considerably shorter latency than fear responses that we observed in visual cortex. Notably, fast amygdala responses were limited to low spatial frequency components of fearful faces, as predicted by magnocellular inputs to amygdala. Furthermore, fast amygdala responses were not evoked by photographs of arousing scenes, which is indicative of selective early reactivity to socially relevant visual information conveyed by fearful faces. These data therefore support the existence of a phylogenetically old subcortical pathway providing fast, but coarse, threat-related signals
to human amygdala.
Accessibility: Document exist in file
Language:
eng
Author:
Méndez-Bértolo, C.
Secondary author(s):
Moratti, S., Toledano, R., Lopez-Sosa, F., Martínez-Alvarez, R., Mah, Y., Vuilleumier, P., Gil-Nagel, A., Strange, B.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Méndez-Bértolo, C., Moratti, S., Toledano, R., Lopez-Sosa, F., Martínez-Alvarez, R., … Strange, B. (2016). A fast pathway for fear in human amygdala. Nature Neuroscience, 19(8), 1041-1049. https://doi.org/10.1038/nn.4324
2-year Impact Factor: 17.839|2016
Impact factor notes: Impact factor not available yet for 2018
Times cited: 211|2024-02-07
Indexed document: Yes
Quartile: Q1
Keywords: Amygdala / Fear / Psychology

A fast pathway for fear in human amygdala

A fast pathway for fear in human amygdala
DocumentA ventromedial prefrontal dysrhythmia in obsessive-compulsive disorder is attenuated by nucleus accumbens deep brain stimulation2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

Reference code: PT/FB/BL-2012-119
Location: Arquivo PCA - Pastas 20/2012
Title:
119 - Dynamic cortical and nucleus accumbens networks in humans: combining intracranial and MEG recordings
Duration: 2013-06 - 2016-10
Researcher(s):
Bryan Strange, Javier J. Gonzalez-Rosa, Juan A. Barcia, Stephan Moratti, Raffael Kaplan, Marijn Kroe
Institution(s): Laboratory for Clinical Neuroscience, Centre for Biomedical Technology (CTB), Technology University of Madrid (UPM) and Fundación para la Investigación Biomédica del Hospital Clínico San Carlos - Universidad Complutense de Madrid. Instituto de Investigación Sanitario IdISSC (Spain)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
2 Articles
2 posters
Language: eng
Author:
Strange, B.
Secondary author(s):
Gonzalez-Rosa, J., Barcia, J., Moratti, S., Kaplan, R., Kroe, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Biopsychological problems / Anxiety disorders / Brain structure and function / Cognitive processes / Intervention

Reference code: PT/FB/BL-2012-119.08
Location: Arquivo PCA - Pastas 20/2012
Title:
A ventromedial prefrontal dysrhythmia in obsessive-compulsive disorder is attenuated by nucleus accumbens deep brain stimulation
Publication year: 2021
URL:
https://www.brainstimjrnl.com/article/S1935-861X(21)00099-1/fulltext
Abstract/Results: ABSTRACT:
BACKGROUND
Obsessive-compulsive disorder (OCD) has consistently been linked to abnormal frontostriatal activity. The electrophysiological disruption in this circuit, however, remains to be characterized.
OBJECTIVE/HYPOTHESIS
The primary goal of this study was to investigate the neuronal synchronization in OCD patients. We predicted aberrant oscillatory activity in frontal regions compared to healthy control subjects, which would be alleviated by deep brain stimulation (DBS) of the nucleus accumbens (NAc).
METHODS
We compared scalp EEG recordings from nine patients with OCD treated with NAc-DBS with recordings from healthy controls, matched for age and gender. Within the patient group, EEG activity was compared with DBS turned off vs. stimulation at typical clinical settings (3.5 V, frequency of stimulation 130 Hz, pulse width 60 µs). In addition, intracranial EEG was recorded directly from depth macroelectrodes in the NAc in four OCD patients.
RESULTS
Cross-frequency coupling between the phase of alpha/low beta oscillations and amplitude of high gamma was significantly increased over midline frontal and parietal electrodes in patients when stimulation was turned off, compared to controls. Critically, in patients, beta (16–25 Hz) -gamma (110–166 Hz) phase amplitude coupling source localized to the ventromedial prefrontal cortex, and was reduced when NAc-DBS was active. In contrast, intracranial EEG recordings showed no beta-gamma phase amplitude coupling. The contribution of non-sinusoidal beta waveforms to this coupling are reported.
CONCLUSION
We reveal an increased beta-gamma phase amplitude coupling in fronto-central scalp sensors in patients suffering from OCD, compared to healthy controls, which may derive from ventromedial prefrontal regions implicated in OCD and is normalized by DBS of the nucleus accumbens. This aberrant cross-frequency coupling could represent a biomarker of OCD, as well as a target for novel therapeutic approaches.
Accessibility: Document exits in file
Language:
eng
Author:
Treu, S.
Secondary author(s):
Gonzalez-Rosa, J. J., Soto-Leon, V., Lozano-Soldevilla, D., Oliviero, A., Lopez-Sosa, F., Reneses-Prieto, B., Barcia, J. A., Strange, B. A.
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Treu, S., Gonzalez-Rosa, J. J., Soto-Leon, V., Lozano-Soldevilla, D., Oliviero, A., Lopez-Sosa, F., …, Strange, B. A. (2021). A ventromedial prefrontal dysrhythmia in obsessive-compulsive disorder is attenuated by nucleus accumbens deep brain stimulation. Brain Stimulation, 14(4), 761-770. https://doi.org/10.1016/j.brs.2021.04.028
2-year Impact Factor: 9.184|2021
Times cited: 7|2024-02-14
Indexed document: Yes
Quartile: Q1
Keywords: Obsessive-compulsive disorder / Deep brain stimulation / EEG / Nucleus accumbens / Ventromedial frontal cross-frequency coupling

A ventromedial prefrontal dysrhythmia in obsessive-compulsive disorder is attenuated by nucleus accumbens deep brain stimulation

A ventromedial prefrontal dysrhythmia in obsessive-compulsive disorder is attenuated by nucleus accumbens deep brain stimulation