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File495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly2015-072022-03

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology
DocumentNeuromodulation as a cognitive enhancement strategy in healthy older adults: promises and pitfalls2016

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

Reference code: PT/FB/BL-2014-495.02
Location: BF-GMS
Title:
Neuromodulation as a cognitive enhancement strategy in healthy older adults: promises and pitfalls
Publication year: 2016
URL:
http://www.tandfonline.com/doi/abs/10.1080/13825585.2016.1176986?tab=permissions&scroll=top
Abstract/Results: ABSTRACT:
Increases in life expectancy have been followed by an upsurge of age-associated cognitive decline. Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have risen as promising approaches to prevent or delay such cognitive decline. However, consensus has not yet been reached about their efficacy in improving cognitive functioning in healthy older adults. Here we review the effects of TMS and tDCS on cognitive abilities in healthy older adults. Despite considerable variability in the targeted cognitive domains, design features and outcomes, the results generally show an enhancement or uniform benefit across studies. Most studies employed tDCS, suggesting that this technique is particularly well-suited for cognitive enhancement. Further work is required to determine the viability of these techniques as tools for long-term cognitive improvement. Importantly, the combination of TMS/tDCS with other cognitive enhancement strategies may be a promising strategy to alleviate the cognitive decline associated with the healthy aging process.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Martins, A.
Secondary author(s):
Fregni, F., Simis, M., Almeida, J.
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Martins, A., Fregni, F., Simis, M., & Almeida, J. (2016). Neuromodulation as a cognitive enhancement strategy in healthy older adults: promises and pitfalls. Aging, Neuropsychology, and Cognition, 24(2), 158-185. https://doi.org/10.1080/13825585.2016.1176986
2-year Impact Factor: 1.763|2016
Times cited: 13|2024-02-07
Indexed document: Yes
Quartile: Q3
Keywords: Neuromodulation / Transcranial magnetic stimulation (TMS) / Cognitive function / Healthy / Transcranial direct current stimulation (TDCS)
DocumentMemory enhancement in aging - the role of cognitive training combined with tDCS: preliminary results2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

Reference code: PT/FB/BL-2014-495.03
Location: BF-GMS
Title:
Memory enhancement in aging - the role of cognitive training combined with tDCS: preliminary results
Publication year: 2017
URL:
http://www.brainstimjrnl.com/article/S1935-861X(17)30216-4/abstract
Abstract/Results: Document does not exist in file
Language: eng
Author:
Amaral, L.
Secondary author(s):
Martins, A., Alves, J., Fernandes, F., Fregni, F., Simis, M., Almeida, J., Simões, M. R.
Document type:
Abstract
Number of reproductions:
1
Reference:
Amaral, L., Martins, A. R., Alves, J., Fernandes, F., Fregni, F., Simis, S., Almeida, J., Simões, M. R. (2017). Memory enhancement in aging - the role of cognitive training combined with tDCS: preliminary results (Conference Abstract). Brain Stimulation, 10(2), 411. https://doi.org/10.1016/j.brs.2017.01.216
Indexed document: Yes
Keywords: Transcranial direct current stimulation (TDCS) / Cognitive training / Aging / Memory
DocumentAlzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog): Normative Data for the Portuguese Population2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

Reference code: PT/FB/BL-2014-495.04
Location: BF-GMS
Title:
Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog): Normative Data for the Portuguese Population
Publication year: 2018
URL:
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8859/5353
Abstract/Results: ABSTRACT:
INTRODUCTION:
The Alzheimer’s Disease Assessment Scale – Cognitive Subscale is a brief battery developed to assess cognitive functioning in Alzheimer’s disease that encompasses the core characteristics of cognitive decline (e.g. memory, language, praxis, constructive ability and orientation). The early detection, as well as the monitoring of cognitive decline along disease progression, is extremely important in clinical care and interventional research. The main goals of the present study were to analyze the psychometric properties of the Portuguese version of the Alzheimer’s Disease Assessment Scale – Cognitive Subscale, and to establish normative values for the Portuguese population.
MATERIALS AND METHODS:
The Portuguese version of Alzheimer’s Disease Assessment Scale – Cognitive Subscale was administered to 223 cognitively healthy participants according to a standard assessment protocol consisting of the Mini-Mental State Examination, the Montreal Cognitive Assessment and the Adults and Older Adults Functional Assessment Inventory. Normal performance on the
assessment protocol was the inclusion criteria for the study.
RESULTS:
The Alzheimer’s Disease Assessment Scale – Cognitive Subscale revealed good psychometric properties when used in the Portuguese population. Age was the main predictor of the Alzheimer’s Disease Assessment Scale – Cognitive Subscale total score
(R2 = 0.123), whereas the influence of education level was lower (R2 = 0.027). These two variables explained 14.4% of the variance on the Alzheimer’s Disease Assessment Scale – Cognitive Subscale scores and were used to stratify the normative values for the Portuguese population presented here.
CONCLUSION:
On the total sample, the average total score in the Alzheimer’s Disease Assessment Scale – Cognitive Subscale was 6 points. The normative data were determined according to age and educational level as these were the sociodemographic variables that
significantly contributed to the prediction of the Alzheimer’s Disease Assessment Scale – Cognitive Subscale total scores, explaining 14.4% of their variance. The normative data are of the utmost importance to ensure proper use of this battery in Portugal.
Accessibility: Document exists in file
Language:
eng
Author:
Nogueira, J.
Secondary author(s):
Freitas, S., Duro, D., Tábuas-Pereira, M., Guerreiros, M., Almeida, J., Santana, I.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Nogueira, J., Freitas, S., Duro, D., Tábuas-Pereira, M., Guerreiros, M., Almeida, J., & Santana, I. (2018). Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog): Normative Data for the Portuguese Population. Acta Médica Portuguesa, 31(2), 94-100. https://doi.org/10.20344/amp.8859
2-year Impact Factor: 0.581|2018
Times cited: 6|2024-02-09
Indexed document: Yes
Quartile: Q4
Keywords: Alzheimer disease / Cognitive dysfunction / Neuropsychological tests / Portugal / Surveys and questionnaires / Translations

Alzheimer’s Disease Assessment Scale - Cognitive subscale (ADAS-Cog): Normative data for the Portuguese population

Alzheimer’s Disease Assessment Scale - Cognitive subscale (ADAS-Cog): Normative data for the Portuguese population
DocumentValidation study of the Alzheimer’s disease assessment scale–cognitive subscale (ADAS-Cog) for the Portuguese patients with mild cognitive impairment and Alzheimer’s disease2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

Reference code: PT/FB/BL-2014-495.05
Location: BF-GMS
Title:
Validation study of the Alzheimer’s disease assessment scale–cognitive subscale (ADAS-Cog) for the Portuguese patients with mild cognitive impairment and Alzheimer’s disease
Publication year: 2018
URL:
https://www.tandfonline.com/doi/full/10.1080/13854046.2018.1454511
Abstract/Results: ABSTRACT:
OBJECTIVE:
The Alzheimer’s disease assessment scale–Cognitive Subscale (ADAS-Cog) is a battery to assess cognitive performance in Alzheimer’s disease (AD) and was developed according to the core characteristics of cognitive decline in AD: memory, language, praxis, constructive ability, and orientation. The aim of this study was to explore the diagnostic accuracy and discriminative capacity of the ADAS-Cog for Mild Cognitive Impairment (MCI) and AD, using cut-off points for the Portuguese population. METHOD:
The European Portuguese version of the ADAS-Cog was administrated to 650 participants, divided into a control group (n = 210), an MCI group (n = 240), and an AD group (n = 200). The clinical groups fulfilled standard international diagnostic criteria. Controls were healthy cognitive participants actively integrated in the community. The neuropsychological assessment protocol included the ADAS-Cog, the Mini Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), and the Adults and Older Adults Functional Assessment Inventory (IAFAI).
RESULTS: The ADAS-Cog revealed good psychometric indicators, and the total scores were significantly different between the three groups (p < .001: Control < MCI < AD). The optimal cut-off points established were: MCI > 9 points (AUC = .835; sensitivity = 58% and specificity = 91%) and AD > 12 points (AUC = .996; sensitivity = 94% and specificity = 98%).
CONCLUSIONS: Our findings confirmed the capacity of the ADAS-Cog total score to identify cognitive impairment in AD patients, with poor sensitivity for MCI, in a Portuguese cohort.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Nogueira, J.
Secondary author(s):
Freitas, S., Duro, D., Almeida, J., Santana, I.
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Nogueira, J., Freitas, S., Duro, D., Almeida, J., & Santana, I. (2018). Validation study of the Alzheimer’s disease assessment scale–cognitive subscale (ADAS-Cog) for the Portuguese patients with mild cognitive impairment and Alzheimer’s disease. Clinical Neuropsychologist, 32(Supplement 1), 46-59. https://doi.org/10.1080/13854046.2018.1454511
2-year Impact Factor: 2.006|2018
Times cited: 22|2024-02-09
Indexed document: Yes
Quartile: Q3
Keywords: ADAS-Cog / Neuropsychological assessment / Mild cognitive impairment / Alzheimer’s disease / Dementia
DocumentPolarity-specific transcranial direct current stimulation effects on object-selective neural responses in the inferior parietal lobe2017

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

Reference code: PT/FB/BL-2014-495.06
Location: BF-GMS
Title:
Polarity-specific transcranial direct current stimulation effects on object-selective neural responses in the inferior parietal lobe
Publication year: 2017
URL:
https://www.sciencedirect.com/science/article/abs/pii/S0010945217302204?via%3Dihub
Abstract/Results: ABSTRACT:
Neuromodulation techniques such as transcranial direct current stimulation (tDCS) are routinely used for treating neurological and neuropsychiatric disorders, and for enhancement of cognitive abilities. Recently, their effectiveness in modulating behavioral and neural responses has been questioned. Here we use excitatory and inhibitory tDCS prior to a functional magnetic resonance imaging (fMRI) experiment to show that neural responses for an area's preferred stimuli depend on the polarity of stimulation. This is an important, yet overlooked, data point in demonstrating the effectiveness of these stimulation techniques. Our results show that response preferences in the target area are dependent on the polarity of the tDCS session preceding the fMRI experiment these preferences are less distinct in the cathodal than in the anodal session. As such, we show unequivocally that tDCS modulates neural responses. This result is of the utmost importance in demonstrating the effectiveness of tDCS for clinical and experimental purposes. (C) 2017 Elsevier Ltd. All rights reserved.
Accessibility: Document does not exist in file
Language:
eng
Author:
Almeida, J.
Secondary author(s):
Martins, A. R., Bergström, F., Amaral, L., Freixo, A., Ganho-Ávila, A., Kristensen, S., Lee, D., Nogueira, J., Ruttorf, M.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Almeida, J., Martins, A. R., Bergström, F., Amaral, L., Freixo, A., Ganho-Ávila, A., Kristensen, S., Lee, D., Nogueira, J., & Ruttorf, M. (2017). Polarity-specific transcranial direct current stimulation effects on object-selective neural responses in the inferior parietal lobe. Cortex, 94, 176-181. https://doi.org/10.1016/j.cortex.2017.07.001
2-year Impact Factor: 4.907|2017
Times cited: 13|2024-02-08
Indexed document: Yes
Quartile: Q1
Keywords: tDCS / fMRI / Neuromodulation / IPL / Tools
DocumentFinal report - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly2018

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

Reference code: PT/FB/BL-2014-495.01
Location: BF-GMS
Title:
Final report - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Publication year: 2018
Abstract/Results:
ABSTRACT:
BACKGROUND
Cognitive training (CT) has been widely implemented and it is currently accepted as the most promising method to alleviate cognitive decline. Several techniques have been combined with CT to explore the synergetic effects and, recently, a beneficial effect has been shown after the combination with transcranial direct current stimulation (tDCS).
AIMS
Here we combined multiple sessions CT with tDCS to assess verbal episodic memory improvement in healthy elderly subjects, compared with sham and a wait list group.
METHOD
We tested whether CT and excitatory tDCS over the left dorsolateral prefrontal cortex (lDLPFC) or right cerebellar cortex (rCC) facilitates verbal episodic memory, compared with sham stimulation and a wait list control group. CT was applied daily for 1 hour, after 20 minutes of tDCS, over 12 sessions. Performance on memory and other cognitive tasks was evaluated at baseline and postintervention, using behavioral and neuroimaging tools. Participants were healthy elderly, = 60 years, right-handed, without history of neuropsychiatric disease.
RESULTS
Data suggest an improvement in verbal episodic memory tasks in the groups receiving CT + tDCS. Interestingly, there is a greater improvement and consistency in the group receiving CT+ tDCS in the rCC. Neuroimaging data supports the results from the neuropsychological assessment. Specifically, tDCS over the right cerebellum + CT increased the functional connectivity in the left hippocampus.
CONCLUSIONS
These data suggest that CT and neuromodulation hold promise as a means to enhance cognitive functions in healthy elderly. Greater light is also shed on the role of the cerebellar cortex in cognitive processing.
Accessibility: Document exists in file
Language:
eng
Author:
Simões, M. R.
Secondary author(s):
Fernandes, F., Alves, J. E., Simis, M. , Martins, A. R., Almeida, J.
Document type:
Final report
Number of reproductions:
1
Reference:
Simões, M. R., Fernandes, F., Alves, J. E., Simis, M., Martins, A. R., & Almeida, J. (2018). Final report - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly.
Indexed document: No
Keywords: Aging / Cognitive enhancement / tDCS / fMRI / Cerebellum

Final report - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly

Final report - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
DocumentThe cerebellum is causally involved in episodic memory under aging2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

Reference code: PT/FB/BL-2014-495.07
Location: BF-GMS
Title:
The cerebellum is causally involved in episodic memory under aging
Publication year: 2023
URL:
https://link.springer.com/article/10.1007/s11357-023-00738-0
Abstract/Results: ABSTRACT:
Episodic memory decline is a major signature of both normal and pathological aging. Many neural regions have been implicated in the processes subserving both episodic memory and typical aging decline. Here, we demonstrate that the cerebellum is causally involved episodic memory under aging. We show that a 12-day neurostimulation program delivered to the right cerebellum led to improvements in episodic memory performance under healthy aging that long outlast the stimulation period — healthy elderly individuals show episodic memory improvement both immediately after the intervention program and in a 4-month follow-up. These results demonstrate the causal relevance of the cerebellum in processes associated with long-term episodic memory, potentially highlighting its role in regulating and maintaining cognitive processing. Moreover, they point to the importance of non-pharmacological interventions that prevent or diminish cognitive decline in healthy aging.
Accessibility: Document exists in file
Language:
eng
Author:
Almeida, J.
Secondary author(s):
Martins, A. R., Amaral, L., Valério, D., Bukhari, Q., Schu, G., Nogueira, J., Spínola, M., Soleimani, G., Fernandes, F., Silva, A. R., Fregni, F., Simis, M., Simões, M., Peres, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Almeida, J., Martins, A. R., Amaral, L., Valério, D., Bukhari, Q., Schu, G., Nogueira, J., Spínola, M., Soleimani, G., Fernandes, F., Silva, A. R., Fregni, F., Simis, M., Simões, M., & Peres, A. (2023). The cerebellum is causally involved in episodic memory under aging. GeroScience, 45(4), 2267–2287. https://doi.org/10.1007/s11357-023-00738-0
2-year Impact Factor: 5.3|2023
Times cited: 2|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Episodic memory decline / Cerebellum / Neurostimulation

The cerebellum is causally involved in episodic memory under aging

The cerebellum is causally involved in episodic memory under aging