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File002 - Neurobiological effects of Lourdes water: An fMRI study2019-012021-09

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-002
Location: BF-GMS
Title:
002 - Neurobiological effects of Lourdes water: An fMRI study
Duration: 2019-01 - 2021-09
Researcher(s):
Anne Schienle, Albert Wabnegger
Institution(s): Clinical Psychology, University of Graz (Austria)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Schienle, A.
Secondary author(s):
Wabnegger, A.
Number of reproductions:
3
Keywords:
Lourdes water / Placebo / Resting state connectivity / fMRI / Psychophysiology and Parapsychology

DocumentBelief in the miracles of Lourdes: A voxel-based morphometry study2020

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-002
Location: BF-GMS
Title:
002 - Neurobiological effects of Lourdes water: An fMRI study
Duration: 2019-01 - 2021-09
Researcher(s):
Anne Schienle, Albert Wabnegger
Institution(s): Clinical Psychology, University of Graz (Austria)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Schienle, A.
Secondary author(s):
Wabnegger, A.
Number of reproductions:
3
Keywords:
Lourdes water / Placebo / Resting state connectivity / fMRI / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2018-002.02
Location: BF-GMS
Title:
Belief in the miracles of Lourdes: A voxel-based morphometry study
Publication year: 2020
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955922/
Abstract/Results: ABSTRACT:
BACKGROUND
It has been shown that particular religious beliefs and practices are associated with brain function and structure. The present voxel-based morphometry study investigated the correlation between the belief in the miracles of Lourdes (a major Catholic pilgrimage site) and gray matter volume in specific brain regions associated with theory of mind (ToM).
METHOD
Structural brain data from 84 women (mean age: 25 years; no current somatic illness; 80% Roman-Catholic) were correlated with self-report measures on belief in miracles, religious–spiritual well-being, and psychological problems. Selected brain regions of the ToM network included the temporoparietal junction (TPJ), hippocampus, amygdala, and medial prefrontal cortex (MPFC).
RESULTS
The belief in the miracles of Lourdes was positively correlated with general religiousness and with feelings of connectedness; there was no association with psychological problems. Belief in miracles of Lourdes correlated positively with TPJ volume and negatively with MPFC volume.
CONCLUSION
Belief in the miracles was associated with brain volume in regions involved in mentalizing and self-control.
Accessibility: Document exists in file
Language:
eng
Author:
Schienle, A.
Secondary author(s):
Höfler, C., Wabnegger, A.
Document type:
Article
Number of reproductions:
3
Reference:
Schienle, A., Höfler, C., & Wabnegger, A. (2020). Belief in the miracles of Lourdes: A voxel-based morphometry study. Brain and Behavior, 10(1): e01481. doi: 10.1002/brb3.1481
2-year Impact Factor: 2.708|2020
Times cited: 4|2022-03-09
Indexed document: Yes
Quartile: Q3
Keywords: Miracles of Lourdes / Religious-spiritual well-being / Specific religious beliefs / Voxel-based morphometry

Belief in the miracles of Lourdes: A voxel-based morphometry study

Belief in the miracles of Lourdes: A voxel-based morphometry study

DocumentPlacebo effects in the context of religious beliefs and practices: A resting-state functional connectivity study2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-002
Location: BF-GMS
Title:
002 - Neurobiological effects of Lourdes water: An fMRI study
Duration: 2019-01 - 2021-09
Researcher(s):
Anne Schienle, Albert Wabnegger
Institution(s): Clinical Psychology, University of Graz (Austria)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Schienle, A.
Secondary author(s):
Wabnegger, A.
Number of reproductions:
3
Keywords:
Lourdes water / Placebo / Resting state connectivity / fMRI / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2018-002.03
Location: BF-GMS
Title:
Placebo effects in the context of religious beliefs and practices: A resting-state functional connectivity study
Publication year: 2021
URL:
https://www.frontiersin.org/articles/10.3389/fnbeh.2021.653359/full
Abstract/Results: ABSTRACT:
BACKGROUND
Placebos (inert substances or procedures) can positively influence a person’s psychological and physical well-being, which is accompanied by specific changes in brain activity. There are many different types of placebos with different effects on health-related variables. This study investigated placebo effects in the context of religious beliefs and practices. The participants received an inert substance (tap water) along with the verbal suggestion that the water would come from the sanctuary in Lourdes (a major Catholic pilgrimage site with reports of miracle cures). We investigated changes in resting-state functional connectivity (rsFC) in three brain networks (default-mode, salience, cognitive control) associated with the drinking of the placebo water.
METHODS
A total of 37 females with the belief that water from the sanctuary in Lourdes has positive effects on their spiritual, emotional, and physical well-being participated in this placebo study with two sessions. The participants drank tap water that was labeled “Lourdes water” (placebo) before a 15-min resting-state scan in one session. In the other (control) session, they received tap water labeled as tap water. The participants rated their affective state (valence, arousal) during the session and were interviewed concerning specific thoughts, feelings, and bodily sensations directly after each of the two sessions.
RESULTS
The placebo reduced rsFC in the frontoparietal cognitive control network and increased rsFC in the salience network (insular-cerebellar connectivity). During the session, the participants rated their affective state as very pleasant and calm. The ratings did not differ between the two conditions. Immediately after the session, the participants reported increased intensity of pleasant bodily sensations (e.g., feelings of warmth, tingling) and feelings (e.g., gratefulness) for the “Lourdes water” condition.
CONCLUSIONS
The present findings provide the first evidence that placebos in the context of religious beliefs and practices can change the experience of emotional salience and cognitive control which is accompanied by connectivity changes in the associated brain networks.
Accessibility: Document exists in file
Language:
eng
Author:
Schienle, A.
Secondary author(s):
Gremsl, A., Wabnegger, A.
Document type:
Article
Number of reproductions:
3
Reference:
Schienle, A., Gremsl, A., & Wabnegger, A. (2021). Placebo effects in the context of religious beliefs and practices: A resting-state functional connectivity study. Frontiers in Behavioral Neuroscience, 15: 653359. doi: 10.3389/fnbeh.2021.653359
2-year Impact Factor: 3.558|2020
Impact factor notes: Impact factor not available yet for 2021
Times cited: 0|2022-03-09
Indexed document: Yes
Quartile: Q1
Keywords: Resting-state functional connectivity / Religious belief / Fronto-parietal cognitive control network / Salience network / Placebo

Placebo effects in the context of religious beliefs and practices: A resting-state functional connectivity study

Placebo effects in the context of religious beliefs and practices: A resting-state functional connectivity study

DocumentFinal report - Neurobiological effects of Lourdes water: An fMRI study2021

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-002
Location: BF-GMS
Title:
002 - Neurobiological effects of Lourdes water: An fMRI study
Duration: 2019-01 - 2021-09
Researcher(s):
Anne Schienle, Albert Wabnegger
Institution(s): Clinical Psychology, University of Graz (Austria)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Schienle, A.
Secondary author(s):
Wabnegger, A.
Number of reproductions:
3
Keywords:
Lourdes water / Placebo / Resting state connectivity / fMRI / Psychophysiology and Parapsychology

Reference code: PT/FB/BL-2018-002.01
Location: BF-GMS
Title:
Final report - Neurobiological effects of Lourdes water: An fMRI study
Publication year: 2021
URL:
https://www.bial.com/media/3758/neurobiological-effects-of-lourdes-water.pdf
Abstract/Results: ABSTRACT:
BACKGROUND
Water from Lourdes (a Catholic pilgrimage site in France) has been associated with medical miracles. From a skeptical point of view, Lourdes's water is a placebo.
AIMS
The project investigated neurobiological correlates of the belief in the healing power of Lourdes water.
METHOD
In the conducted studies (with structural/ functional magnetic resonance imaging/ resting-state functional connectivity; rsFC), participants drank either tap water that was labeled ‘Lourdes water’ (placebo), water from the sanctuary in Lourdes (verum), or ‘tap water’ (labeled as tap water; control). Additionally, they evaluated their subjective state (emotions, thoughts, somatic symptoms).
RESULTS
The belief in the miracles of Lourdes was positively associated with brain volume in the temporo-parietal junction (TPJ) and negatively with volume in the medial prefrontal cortex (MPFC). The mentioned brain regions are involved in mentalizing and self-control. The placebo reduced rsFC in the fronto-parietal cognitive control network and increased rsFC in the salience network (insular-cerebellar connectivity). The three groups did not differ in the intensity of reported emotions, thoughts, somatic symptoms, and whole-brain activity during the experiment. After the fMRI session, the placebo group reported increased intensity of bodily sensations (e.g. feelings of warmth, tingling) and positive emotions (e.g., gratefulness).
CONCLUSIONS
The findings provide the first evidence that the belief in the miracles of Lourdes is associated with brain activity in large-scale functional networks and brain volume in regions involved in processes related to self-regulation and self-awareness.
Accessibility: Document exists in file
Language:
eng
Author:
Schienle, A.
Secondary author(s):
Wabnegger, A.
Document type:
Final report
Number of reproductions:
3
Reference:
Schienle, A., & Wabnegger, A. (2021). Final report - Neurobiological effects of Lourdes water: An fMRI study.
Indexed document: No
Keywords: Lourdes water / Resting state connectivity / Placebo / Magnetic resonance imaging

Final report - Neurobiological effects of Lourdes water: An fMRI study

Final report - Neurobiological effects of Lourdes water: An fMRI study