Reference code: | PT/FB/BL-2018-106.05 |
Location: | BF-GMS
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Title:
| Thalamocortical interactions shape hierarchical neural variability during stimulus perception
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Publication year: | 2024
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URL:
| https://doi.org/10.1016/j.isci.2024.110065
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Abstract/Results: | ABSTRACT:
The brain is organized hierarchically to process sensory signals. But, how do functional connections within and across areas contribute to this hierarchical order? We addressed this problem in the thalamocortical network, while monkeys detected vibrotactile stimulus. During this task, we quantified neural variability and directed functional connectivity in simultaneously recorded neurons sharing the cutaneous receptive field within and across VPL and areas 3b and 1. Before stimulus onset, VPL and area 3b exhibited similar fast dynamics while area 1 showed slower timescales. During the stimulus presence, inter-trial neural variability increased along the network VPL-3b-1 while VPL established two main feedforward pathways with areas 3b and 1 to process the stimulus. This lower variability of VPL and area 3b was found to regulate feedforward thalamocortical pathways. Instead, intra-cortical interactions were only anticipated by higher intrinsic timescales in area 1. Overall, our results provide evidence of hierarchical functional roles along the thalamocortical network.
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Accessibility: | Document exists in file
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Language:
| eng
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Author:
| Tauste Campo, A.
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Secondary author(s):
| Zainos, A., Vázquez, Y., Adell Segarra, R., Álvarez, M., Deco, G., Díaz, H., Parra, S., Romo, R., Rossi-Pool, R.
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Document type:
| Article
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Number of reproductions:
| 1
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Reference:
| Tauste Campo, A., Zainos, A., Vázquez, Y., Adell Segarra, R., Álvarez, M., Deco, G., Díaz, H., Parra, S., Romo, R., & Rossi-Pool, R. (2024). Thalamocortical interactions shape hierarchical neural variability during stimulus perception. iScience, 27(7), 110065. https://doi.org/10.1016/j.isci.2024.110065
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2-year Impact Factor: | 1.02|2023
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Impact factor notes: | Impact factor not available yet for 2024
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Times cited: | 0|2024-10-15
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Indexed document: | Yes
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Quartile: | Q1
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Keywords: | Somatosensory cortex / Thalamus / Connectivity / Neurons / Driven / Networks
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Thalamocortical interactions shape hierarchical neural variability during stimulus perception |