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File036 - The role of non-verbal behaviour on placebo and nocebo effects. Psychophysiological experiments2021-022024-11

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-036
Location: BF-GMS
Title:
036 - The role of non-verbal behaviour on placebo and nocebo effects. Psychophysiological experiments
Duration: 2021-02 - 2024-11
Researcher(s):
Magne Arve Flaten, Hojjat Daniali, Per Aslaksen, Ted Kaptchuk, Mollie Ruben
Institution(s): Department of Psychology, Norwegian University of Science and Technology, Trondheim (Norway); University of Tromsø (Norway); Harvard Medical School, Boston (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Flaten, M.
Secondary author(s):
Daniali, H., Aslaksen, P., Kaptchuk, T., Ruben, M.
Number of reproductions:
1
Keywords:
Placebo and nocebo effect / Heart rate variability / Non-verbal behaviour / Skin conductance response / Psychophysiology
DocumentA global meta-analysis of depression, anxiety, and stress before and during COVID-192023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-036
Location: BF-GMS
Title:
036 - The role of non-verbal behaviour on placebo and nocebo effects. Psychophysiological experiments
Duration: 2021-02 - 2024-11
Researcher(s):
Magne Arve Flaten, Hojjat Daniali, Per Aslaksen, Ted Kaptchuk, Mollie Ruben
Institution(s): Department of Psychology, Norwegian University of Science and Technology, Trondheim (Norway); University of Tromsø (Norway); Harvard Medical School, Boston (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Flaten, M.
Secondary author(s):
Daniali, H., Aslaksen, P., Kaptchuk, T., Ruben, M.
Number of reproductions:
1
Keywords:
Placebo and nocebo effect / Heart rate variability / Non-verbal behaviour / Skin conductance response / Psychophysiology

Reference code: PT/FB/BL-2020-036.02
Location: BF-GMS
Title:
A global meta-analysis of depression, anxiety, and stress before and during COVID-19
Publication year: 2023
URL:
https://doi.org/10.1037/hea0001259
Abstract/Results: ABSTRACT:
Objective: This meta-analysis compared negative emotions (NEs) as depression, anxiety, and stress, from before the pandemic to during the pandemic. Method: A total of 59 studies (19 before, 37 during-pandemic, and 3 that included both) using the Depression, Anxiety and Stress Scale (DASS) were included. A random effects model estimated the means of NEs before and during the pandemic. Results: Studies from 47 countries involving 193,337 participants were included. Globally, NEs increased during the pandemic, and depression had the largest elevation. In Asia, depression and stress were elevated, whereas in Europe, only depression increased, and in America, no differences in NEs between before and during the pandemic were observed. The later time phase of the pandemic was associated with lower stress globally, and lower stress and anxiety in Europe. Being younger was associated with more stress globally, and being older was associated with higher anxiety in Asia. Students had higher anxiety globally, and higher NEs in all three aspects in Europe compared to the general population. The COVID-19 infection rate was associated with more stress globally, and stress and anxiety in Europe. During the pandemic, females reported higher levels of depression, anxiety, and stress compared to males, most pronounced in Europe. Conclusion: NEs increased during the pandemic, with younger and student populations, females and Asians having the highest elevations.
Accessibility: Document exists in file
Language:
eng
Author:
Daniali, H.
Secondary author(s):
Martinussen, M., Flaten, M. A.
Document type:
Article
Number of reproductions:
1
Percentiles:
3
Reference:
Daniali, H., Martinussen, M., & Flaten, M. A. (2023). A global meta-analysis of depression, anxiety, and stress before and during COVID-19. Health Psychology, 42(2), 124-138. https://doi.org/10.1037/hea0001259
2-year Impact Factor: 4.200|2022
Impact factor notes: Impact factor not available yet for 2023
Times cited: 10|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: COVID-19 pandemic / Depression / Anxiety / Stress / DASS / Global

A global meta-analysis of depression, anxiety, and stress before and during COVID-19

A global meta-analysis of depression, anxiety, and stress before and during COVID-19
DocumentSystematic manipulation of experimenters' non-verbal behaviors for the investigation of pain reports and placebo effects2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-036
Location: BF-GMS
Title:
036 - The role of non-verbal behaviour on placebo and nocebo effects. Psychophysiological experiments
Duration: 2021-02 - 2024-11
Researcher(s):
Magne Arve Flaten, Hojjat Daniali, Per Aslaksen, Ted Kaptchuk, Mollie Ruben
Institution(s): Department of Psychology, Norwegian University of Science and Technology, Trondheim (Norway); University of Tromsø (Norway); Harvard Medical School, Boston (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Flaten, M.
Secondary author(s):
Daniali, H., Aslaksen, P., Kaptchuk, T., Ruben, M.
Number of reproductions:
1
Keywords:
Placebo and nocebo effect / Heart rate variability / Non-verbal behaviour / Skin conductance response / Psychophysiology

Reference code: PT/FB/BL-2020-036.03
Location: BF-GMS
Title:
Systematic manipulation of experimenters' non-verbal behaviors for the investigation of pain reports and placebo effects
Publication year: 2023
URL:
https://doi.org/10.3389/fpsyg.2023.1248127
Abstract/Results: ABSTRACT:
Objective:
Non-verbal behaviors (NBs) of caregivers affect pain reports and placebo effects. However, little experimental research has systematically examined the caregivers' NBs. This study protocol and preparatory study report a systematic manipulation of experimenters' NBs to investigate pain report and placebo effects.
Methods:
We propose an experiment in which videotaped experimenters (VEs) conduct a pain stimulation and a placebo treatment study. The VEs express one positively enhanced NB and keep the other NBs neutral. Participants will be randomized to either the positive facial expressions (+FE), tone of voice (+TV), body movement (+BM), or neutral NBs (i.e., neutral condition; NC) of the VEs. As a preparatory study for proof of concept, two groups of NB coders from Norway and the USA separately rated the degree of NBs (eye contact, body postures and movements, and tone of voice), and impressions of dominance and being in charge, positivity, and expressivity from each NB video. The NB videos had construct validity and reliability. The +BM and +FE were rated as more dominant and in charge than the +TV and the NC. The +FE and +BM were rated as the most positive and expressive NBs, respectively.
Expected results:
+FE will have the largest placebo effects on pain and stress levels. However, transmitting the NBs to patients by VEs is challenging. Moreover, controlling for the effects of research assistants present in the testing room is challenging.
Discussion:
We propose that caregivers' NBs affect pain reports and placebo effects. Moreover, different NBs elicit different impressions, and a better understanding of the role of caregiver NBs requires more rigorous investigations. Lastly, aiming to investigate the caregiver NBs, the varying degrees of micro-NBs and their effects on the formation of impressions should be considered.
Accessibility: Document exists in file
Language:
eng
Author:
Daniali, H.
Secondary author(s):
Ruben, M. A., Flaten, M. A.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Daniali, H., Ruben, M. A., & Flaten, M. A. (2023). Systematic manipulation of experimenters' non-verbal behaviors for the investigation of pain reports and placebo effects. Frontiers in Psychology, 14, 1248127. https://doi.org/10.3389/fpsyg.2023.1248127
2-year Impact Factor: 3.8|2022
Impact factor notes: Impact factor not available yet for 2023
Times cited: 0|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Nonverbal behaviors / Impression formation / Stimuli development / Placebo effects / Subtle contextual factors

Systematic manipulation of experimenters' non-verbal behaviors for the investigation of pain reports and placebo effects

Systematic manipulation of experimenters' non-verbal behaviors for the investigation of pain reports and placebo effects
DocumentThe Effect of singular nonverbal behaviours of experimenters on pain reports2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-036
Location: BF-GMS
Title:
036 - The role of non-verbal behaviour on placebo and nocebo effects. Psychophysiological experiments
Duration: 2021-02 - 2024-11
Researcher(s):
Magne Arve Flaten, Hojjat Daniali, Per Aslaksen, Ted Kaptchuk, Mollie Ruben
Institution(s): Department of Psychology, Norwegian University of Science and Technology, Trondheim (Norway); University of Tromsø (Norway); Harvard Medical School, Boston (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Flaten, M.
Secondary author(s):
Daniali, H., Aslaksen, P., Kaptchuk, T., Ruben, M.
Number of reproductions:
1
Keywords:
Placebo and nocebo effect / Heart rate variability / Non-verbal behaviour / Skin conductance response / Psychophysiology

Reference code: PT/FB/BL-2020-036.04
Location: BF-GMS
Title:
The Effect of singular nonverbal behaviours of experimenters on pain reports
Publication year: 2024
URL:
https://doi.org/10.2147/JPR.S449150
Abstract/Results: ABSTRACT:
Introduction: Studies suggest facial expressions of caregivers may be important in placebo effects; however, this has not been systematically tested. This experiment investigated the effects of caregivers' singular positive nonverbal behaviours (NBs) on pain reports.
Methods: Fifty-one males and 53 females (total of 104) participants were randomized to four groups that were displayed positive facial expressions, tone of voice, body movement, or neutral NBs of videotaped experimenters. Subjective reports of pain, stress, arousal, and cardiac activity were obtained in a pre-test, a conditioning phase, and at a post-test. Four minutes of heat pain was induced in each test, and a placebo cream was administered before the conditioning and post-test in all groups.
Results: There were no differences between the NB groups in the reduced pain. Males had larger reduction in pain in the post-test, and females had lower arousal than the opposite sex. During the conditioning, females had larger reduction in pain ie, unconditioned pain response (UPR). In females, the UPR predicted the reinforced expectation ie, increase in expectations from conditioning to post-test, and fear of minor pain negatively predicted both the UPR and reinforced expectation.
Discussion: Singular NBs of caregiver were weak to enhance placebo effects. Females had lower pain during conditioning, and the UPR amplitude in females was associated with positive expectations. Moreover, for females, fear of minor pain weakened the UPR and expectations of cream.
Conclusion: No NB of caregivers is more effective in reducing pain. Caregivers' NBs are less effective when displayed individually. Males and females may be different in underlying mechanisms of placebo effects.
Accessibility: Document exists in file
Language:
eng
Author:
Daniali, H.
Secondary author(s):
Ruben, M., Aslaksen, P. M., Fiskum, C., Kaptchuk, T., Flaten, M. A.
Document type:
Article
Number of reproductions:
1
Reference:
Daniali, H., Ruben, M. A., Aslaksen, P. M., Fiskum, C., Kaptchuk, T. J., & Flaten, M. A. (2024). The Effect of singular nonverbal behaviours of experimenters on pain reports. Journal of Pain Research, 17, 1345–1360. https://doi.org/10.2147/JPR.S449150
2-year Impact Factor: 2.60|2023
Impact factor notes: Impact factor not available yet for 2024
Times cited: 1|2024-10-08
Indexed document: Yes
Quartile: Q2
Keywords: Placebo effects / Subtle factors / Nonverbal behaviours / Heat pain / Experimenter effects / Pain report

The Effect of singular nonverbal behaviours of experimenters on pain reports

The Effect of singular nonverbal behaviours of experimenters on pain reports
DocumentEffects of open and hidden administration of treatment-related information; A multi-experiment study2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-036
Location: BF-GMS
Title:
036 - The role of non-verbal behaviour on placebo and nocebo effects. Psychophysiological experiments
Duration: 2021-02 - 2024-11
Researcher(s):
Magne Arve Flaten, Hojjat Daniali, Per Aslaksen, Ted Kaptchuk, Mollie Ruben
Institution(s): Department of Psychology, Norwegian University of Science and Technology, Trondheim (Norway); University of Tromsø (Norway); Harvard Medical School, Boston (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Flaten, M.
Secondary author(s):
Daniali, H., Aslaksen, P., Kaptchuk, T., Ruben, M.
Number of reproductions:
1
Keywords:
Placebo and nocebo effect / Heart rate variability / Non-verbal behaviour / Skin conductance response / Psychophysiology

Reference code: PT/FB/BL-2020-036.05
Location: BF-GMS
Title:
Effects of open and hidden administration of treatment-related information; A multi-experiment study
Publication year: 2024
URL:
https://doi.org/10.1080/08870446.2024.2392820
Abstract/Results: ABSTRACT:
Background: Two experiments (E1 and E2; N = 44 and N = 52, respectively) investigated the effect of positive (PI) and neutral information (NI) about a dental procedure, and if the delivery of the information by the treatment team (open administration) or unbeknownst to the treatment team (hidden administration), affected pain.
Methods: Using a mixed design, patients undergoing drilling in a molar were randomized to the NI or PI groups. Before, during, and after treatment, patients reported their pain and stress levels. In E1 the treatment team delivered the information. In E2, an assistant not engaged in the treatment delivered the information.
Results: In the PI group in E1, pain was reduced by 50 % compared to the NI group, and the effects of stress on pain were mitigated. These effects were abolished in E2. The dentist reported having displayed positive nonverbal behaviours (e.g. smiling and longer eye contact) in the PI group in E1, but not in E2.
Discussion: Positive information reduced pain only when administrated openly. There was no effect of positive information administrated hidden from the treatment team. As information was similar in both experiments, factors other than the information most likely reduced pain in the PI group in E1.
Conclusion: Delivering positive information by the treatment team may generate behavioural cues which generate placebo effects.
Accessibility: Document exists in file
Language:
eng
Author:
Daniali, H.
Secondary author(s):
Hunsbeth, P. L., Flaten, M. A.
Document type:
Article
Number of reproductions:
1
Reference:
Daniali, H., Hunsbeth, P. L., & Flaten, M. A. (2024). Effects of open and hidden administration of treatment-related information; A multi-experiment study. Psychology & Health, 1–29. Advance online publication. https://doi.org/10.1080/08870446.2024.2392820
2-year Impact Factor: 0.78|2023
Impact factor notes: Impact factor not available yet for 2024
Times cited: 0|2024-10-15
Indexed document: Yes
Quartile: Q2
Keywords: Open-hidden administration / Contextual factors / Dental pain / Healthcare providers / Placebo effects

Effects of open and hidden administration of treatment-related information; A multi-experiment study

Effects of open and hidden administration of treatment-related information; A multi-experiment study
DocumentSpecifying Contextual Factors; Caregivers' Role in Pain Report and Placebo Effects - The role of caregivers' characteristics and nonverbal behaviours in pain and placebo effects2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-036
Location: BF-GMS
Title:
036 - The role of non-verbal behaviour on placebo and nocebo effects. Psychophysiological experiments
Duration: 2021-02 - 2024-11
Researcher(s):
Magne Arve Flaten, Hojjat Daniali, Per Aslaksen, Ted Kaptchuk, Mollie Ruben
Institution(s): Department of Psychology, Norwegian University of Science and Technology, Trondheim (Norway); University of Tromsø (Norway); Harvard Medical School, Boston (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Flaten, M.
Secondary author(s):
Daniali, H., Aslaksen, P., Kaptchuk, T., Ruben, M.
Number of reproductions:
1
Keywords:
Placebo and nocebo effect / Heart rate variability / Non-verbal behaviour / Skin conductance response / Psychophysiology

Reference code: PT/FB/BL-2020-036.06
Location: BF-GMS
Title:
Specifying Contextual Factors; Caregivers' Role in Pain Report and Placebo Effects - The role of caregivers' characteristics and nonverbal behaviours in pain and placebo effects
Publication year: 2024
URL:
https://hdl.handle.net/11250/3130407
Abstract/Results: ABSTRACT:
In this PhD project, we investigated the role of caregivers’ characteristics, by means of caregivers’ sex/gender and social status, and their nonverbal behaviours on pain reports and placebo effects (i.e., better treatment outcomes due to expectations that effective treatment has been administrated). Our systematic review of the literature revealed that both pain patients and healthy participants reported less pain when interacting with providers of the opposite sex. Furthermore, caregivers displaying higher status, professionalism, and confidence tended to receive lower pain reports and elicit stronger placebo effects. Positive nonverbal behaviours, such as smiling, maintaining eye contact, and using open body gestures, led to lower pain reports and enhanced placebo effects. Conversely, negative nonverbal behaviours, like avoiding eye contact, not smiling, and displaying closed or defensive body gestures, increased pain reports and elicited nocebo effects (i.e., worse treatment outcomes due to a medically inactive factor).
In a dental pain experiment, we observed that the effectiveness of positive treatment information depended on the caregiver and their subtle nonverbal behaviours. Dental patients reported lower pain levels when they received positive treatment information from the dentist performing the treatment. However, the pain-reducing effects of positive information were lost when the information came from an assistant not involved in the treatment. An interview with the dentist suggested that she may have exhibited positive subtle nonverbal behaviours when delivering the information.
We then explored the impact of singular nonverbal behaviours of caregivers as facial expressions, tone of voice and body movements in a pain experiment involving healthy participants. We found that the reduced-pain from pre-test to post-test was similar between all nonverbal behaviours. While our systematic review and dental pain study underscored the influence of caregiver characteristics and nonverbal behaviours on pain reports and placebo effects, the pain experiment showed no significant differences between singular nonverbal behaviours. Consequently, we concluded that examining singular nonverbal behaviours separately might underestimate the effect of nonverbal behaviours.
Overall, our findings underscore the impact of caregiver characteristics and behaviours on pain reports and placebo effects. These insights carry implications for improving therapeutic interventions and patient outcomes.
Accessibility: Document exists in file
Language:
eng
Author:
Daniali, H.
Document type:
Doctoral thesis
Number of reproductions:
1
Reference:
Daniali, H. (2024). Specifying Contextual Factors; Caregivers' Role in Pain Report and Placebo Effects The role of caregivers' characteristics and nonverbal behaviours in pain and placebo effects. https://hdl.handle.net/11250/3130407
Indexed document: No
Keywords: Caregiver / Contextual factors / Experimenter effects / Nonverbal behavior / Nocebo effect / Placebo effect / Pain

Specifying Contextual Factors; Caregivers' Role in Pain Report and Placebo Effects - The role of caregivers' characteristics and nonverbal behaviours in pain and placebo effects

Specifying Contextual Factors; Caregivers' Role in Pain Report and Placebo Effects - The role of caregivers' characteristics and nonverbal behaviours in pain and placebo effects
DocumentFinal report - The role of non verbal behavior on placebo and nocebo effects. Psychophysiological experiments2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-036
Location: BF-GMS
Title:
036 - The role of non-verbal behaviour on placebo and nocebo effects. Psychophysiological experiments
Duration: 2021-02 - 2024-11
Researcher(s):
Magne Arve Flaten, Hojjat Daniali, Per Aslaksen, Ted Kaptchuk, Mollie Ruben
Institution(s): Department of Psychology, Norwegian University of Science and Technology, Trondheim (Norway); University of Tromsø (Norway); Harvard Medical School, Boston (USA)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Article
Language: eng
Author:
Flaten, M.
Secondary author(s):
Daniali, H., Aslaksen, P., Kaptchuk, T., Ruben, M.
Number of reproductions:
1
Keywords:
Placebo and nocebo effect / Heart rate variability / Non-verbal behaviour / Skin conductance response / Psychophysiology

Reference code: PT/FB/BL-2020-036.01
Location: BF-GMS
Title:
Final report - The role of non verbal behavior on placebo and nocebo effects. Psychophysiological experiments
Publication year: 2024
Abstract/Results:
ABSTRACT:
Background:
Nonverbal behaviors (NBs) of healthcare providers impact pain reports and treatment outcomes, however, no investigation so far has systematically investigated the impact of healthcare providers NBs on pain reports and treatment outcomes.
Aims:
The aim of this project was to investigate the role of healthcare providers’ NBs on pain reports and placebo effects.
Methods: The project consisted of one laboratory experiment and analysis of data from a Dental multi experiment . In the laboratory experiment the impact of singular NBs of videotaped experimenters were investigated on pain reports from heat stimulation in 104 healthy participants. Videotaped experimenters instructed participants while displaying only one singular positive NB. In-person experimenters carried out the experiment and received either certain (i.e., all creams are active pain relieving creams) or uncertain (e.g., "the cream is pain relieving 50% of the time, and a placebo the other 50%") information about the cream. The data from the Dental multi experiment investigated the impact of providers NBs on effectiveness of treatment information on dental pain reports.
Results and discussions:
No differences were observed between the singular NBs of videotaped experimenters, however, compared to uncertain in person experimenters, certain in person experimenters received lower pain reports from participants. The dental multi experiment showed that the positive information about the dental treatment reduced pain only when it was delivered by the dentist administering the treatment.
Conclusions:
Even though the singular NBs might not have a discernable impact on pain reports, the overall NBs of healthcare providers still may impact pain reports and treatment outcome.
Language: eng
Author:
Flaten, M. A.
Secondary author(s):
Daniali, H., Ruben, M. A., Aslaksen, P. M., Kaptchuk, T. J.
Document type:
Final report
Number of reproductions:
1
Reference:
Flaten, M. A., Daniali, H., Ruben, M. A., Aslaksen, P. M., & Kaptchuk, T. J. (2024). Final report - The role of nonverbal behavior on placebo and nocebo effects: Psychophysiological experiments.
Indexed document: No
Keywords: Healthcare providers / Nonverbal behaviors / Pain reports / Placebo effects

Final report - The role of non verbal behavior on placebo and nocebo effects. Psychophysiological experiments

Final report - The role of non verbal behavior on placebo and nocebo effects. Psychophysiological experiments