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080 - Mindfulness meditation state and trait through the eyes of brain computational modelling

2021-10

BIAL Foundation Archive
- BIAL Grants
  - 2020 Grants
    - 080 - Mindfulness meditation state and trait through the eyes of brain computational modelling

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2020
Location:	BF-GMS
Title:	2020 Grants
Start date:	2021-01

Reference code:	PT/FB/BL-2020-080
Location:	BF-GMS
Title:	080 - Mindfulness meditation state and trait through the eyes of brain computational modelling
Duration:	2021-10
Researcher(s):	Laura Marzetti
Institution(s):	Department of Neurosciences, Imaging and Clinical Sciences, Università degli Studi "G. d'Annunzio" Chieti - Pescara (Italy)
Abstract/Results:	Contents: Application form Correspondence Research Funding Agreement Progress report Articles
Language:	eng
Notes:	Ongoing project
Author:	Marzetti, L.
Number of reproductions:	3
Keywords:	Meditation / Brain states / Computational modelling / Neuroimaging / Psychophysiology and Parapsychology

Document

Looking through the windows: a study about the dependency of phase-coupling estimates on the data length

2022

BIAL Foundation Archive
- BIAL Grants
  - 2020 Grants
    - 080 - Mindfulness meditation state and trait through the eyes of brain computational modelling
      - Looking through the windows: a study about the dependency of phase-coupling estimates on the data length

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2020
Location:	BF-GMS
Title:	2020 Grants
Start date:	2021-01

Reference code:	PT/FB/BL-2020-080
Location:	BF-GMS
Title:	080 - Mindfulness meditation state and trait through the eyes of brain computational modelling
Duration:	2021-10
Researcher(s):	Laura Marzetti
Institution(s):	Department of Neurosciences, Imaging and Clinical Sciences, Università degli Studi "G. d'Annunzio" Chieti - Pescara (Italy)
Abstract/Results:	Contents: Application form Correspondence Research Funding Agreement Progress report Articles
Language:	eng
Notes:	Ongoing project
Author:	Marzetti, L.
Number of reproductions:	3
Keywords:	Meditation / Brain states / Computational modelling / Neuroimaging / Psychophysiology and Parapsychology

Reference code:	PT/FB/BL-2020-080.02
Location:	BF-GMS
Title:	Looking through the windows: a study about the dependency of phase-coupling estimates on the data length
Publication year:	2022
URL:	https://iopscience.iop.org/article/10.1088/1741-2552/ac542f
Abstract/Results:	Objective. Being able to characterize functional connectivity (FC) state dynamics in a real-time setting, such as in brain–computer interface, neurofeedback or closed-loop neurostimulation frameworks, requires the rapid detection of the statistical dependencies that quantify FC in short windows of data. The aim of this study is to characterize, through extensive realistic simulations, the reliability of FC estimation as a function of the data length. In particular, we focused on FC as measured by phase-coupling (PC) of neuronal oscillations, one of the most functionally relevant neural coupling modes. Approach. We generated synthetic data corresponding to different scenarios by varying the data length, the signal-to-noise ratio (SNR), the phase difference value, the spectral analysis approach (Hilbert or Fourier) and the fractional bandwidth. We compared seven PC metrics, i.e. imaginary part of phase locking value (iPLV), PLV of orthogonalized signals, phase lag index (PLI), debiased weighted PLI, imaginary part of coherency, coherence of orthogonalized signals and lagged coherence. Main results. Our findings show that, for a SNR of at least 10 dB, a data window that contains 5–8 cycles of the oscillation of interest (e.g. a 500–800 ms window at 10 Hz) is generally required to achieve reliable PC estimates. In general, Hilbert-based approaches were associated with higher performance than Fourier-based approaches. Furthermore, the results suggest that, when the analysis is performed in a narrow frequency range, a larger window is required. Significance. The achieved results pave the way to the introduction of best-practice guidelines to be followed when a real-time frequency-specific PC assessment is at target.
Accessibility:	Document exists in file
Language:	eng
Author:	Basti, A.
Secondary author(s):	Chella, F., Guidotti, R. , Ermolova, M., D'Andrea, A., Stenroos, M., Romani, G. L., Pizzela, V., Marzetti, L.
Document type:	Article
Number of reproductions:	3
Reference:	Basti, A., Chella, F., Guidotti, R., Ermolova, M., D’Andrea, A., Stenroos, M., … Marzetti, L. (2022). Looking through the windows: A study about the dependency of phase-coupling estimates on the data length. Journal of Neural Engineering, 19(1). https://doi.org/10.1088/1741-2552/ac542f
2-year Impact Factor:	4.000\|2022
Times cited:	16\|2025-02-17
Indexed document:	Yes
Quartile:	Q2
Keywords:	Functional connectivity / Phase-coupling / Dynamic connectivity / EEG / MEG
Looking through the windows: a study about the dependency of phase-coupling estimates on the data length

Document

Magnetoencephalographic spectral fingerprints differentiate evidence accumulation from saccadic motor preparation in perceptual decision-making

2022

BIAL Foundation Archive
- BIAL Grants
  - 2020 Grants
    - 080 - Mindfulness meditation state and trait through the eyes of brain computational modelling
      - Magnetoencephalographic spectral fingerprints differentiate evidence accumulation from saccadic motor preparation in perceptual decision-making

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2020
Location:	BF-GMS
Title:	2020 Grants
Start date:	2021-01

Reference code:	PT/FB/BL-2020-080
Location:	BF-GMS
Title:	080 - Mindfulness meditation state and trait through the eyes of brain computational modelling
Duration:	2021-10
Researcher(s):	Laura Marzetti
Institution(s):	Department of Neurosciences, Imaging and Clinical Sciences, Università degli Studi "G. d'Annunzio" Chieti - Pescara (Italy)
Abstract/Results:	Contents: Application form Correspondence Research Funding Agreement Progress report Articles
Language:	eng
Notes:	Ongoing project
Author:	Marzetti, L.
Number of reproductions:	3
Keywords:	Meditation / Brain states / Computational modelling / Neuroimaging / Psychophysiology and Parapsychology

Reference code:	PT/FB/BL-2020-080.03
Location:	BF-GMS
Title:	Magnetoencephalographic spectral fingerprints differentiate evidence accumulation from saccadic motor preparation in perceptual decision-making
Publication year:	2022
URL:	https://www.cell.com/iscience/fulltext/S2589-0042(22)01518-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004222015188%3Fshowall%3Dtrue
Abstract/Results:	ABSTRACT: The understanding of the neurobiological basis of perceptual decision-making has been profoundly shaped by studies in the monkey brain in tandem with mathematical models, providing the basis for the formulation of an intentional account of decision-making. Although much progress has been made in human studies, a characterization of the neural underpinnings of an integrative mechanism, where evidence accumulation and the selection and execution of responses are carried out by the same system, remains challenging. Here, by employing magnetoencephalographic recording in combination with an experimental protocol that measures saccadic response and leverages a systematic modulation of evidence levels, we obtained a spectral dissociation between evidence accumulation mechanisms and motor preparation within the same brain region. Specifically, we show that within the dorsomedial parietal cortex alpha power modulation reflects the amount of sensory evidence available while beta power modulations reflect motor preparation, putatively representing the human homolog of the saccadic-related LIP region.
Accessibility:	Document exists in file
Language:	eng
Related objects:	BL-2016-066.05
Author:	D'Andrea, A.
Secondary author(s):	Basti, A., Tosoni, A., Guidotti, R., Chella, F., Michelmann, S., Romani, G. L., Pizzella, V., Marzetti, L
Document type:	Article-d
Number of reproductions:	3
Reference:	D'Andrea, A., Basti, A., Tosoni, A., Guidotti, R., Chella, F., Michelmann, S., Romani, G. L., Pizzella, V., & Marzetti, L. (2022). Magnetoencephalographic spectral fingerprints differentiate evidence accumulation from saccadic motor preparation in perceptual decision-making. iScience, 25(10), 105246. https://doi.org/10.1016/j.isci.2022.105246
2-year Impact Factor:	5.800\|2022
Times cited:	1\|2025-02-17
Indexed document:	Yes
Quartile:	Q1
Keywords:	Biological sciences / Neuroscience / Sensory neuroscience
Magnetoencephalographic spectral fingerprints differentiate evidence accumulation from saccadic motor preparation in perceptual decision-making

Document

Long-term and meditation-specific modulations of brain connectivity revealed through multivariate pattern analysis

2023

BIAL Foundation Archive
- BIAL Grants
  - 2020 Grants
    - 080 - Mindfulness meditation state and trait through the eyes of brain computational modelling
      - Long-term and meditation-specific modulations of brain connectivity revealed through multivariate pattern analysis

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2020
Location:	BF-GMS
Title:	2020 Grants
Start date:	2021-01

Reference code:	PT/FB/BL-2020-080
Location:	BF-GMS
Title:	080 - Mindfulness meditation state and trait through the eyes of brain computational modelling
Duration:	2021-10
Researcher(s):	Laura Marzetti
Institution(s):	Department of Neurosciences, Imaging and Clinical Sciences, Università degli Studi "G. d'Annunzio" Chieti - Pescara (Italy)
Abstract/Results:	Contents: Application form Correspondence Research Funding Agreement Progress report Articles
Language:	eng
Notes:	Ongoing project
Author:	Marzetti, L.
Number of reproductions:	3
Keywords:	Meditation / Brain states / Computational modelling / Neuroimaging / Psychophysiology and Parapsychology

Reference code:	PT/FB/BL-2020-080.04
Location:	BF-GMS
Title:	Long-term and meditation-specific modulations of brain connectivity revealed through multivariate pattern analysis
Publication year:	2023
URL:	https://link.springer.com/article/10.1007/s10548-023-00950-3
Abstract/Results:	ABSTRACT: Neuroimaging studies have provided evidence that extensive meditation practice modifies the functional and structural properties of the human brain, such as large-scale brain region interplay. However, it remains unclear how different meditation styles are involved in the modulation of these large-scale brain networks. Here, using machine learning and fMRI functional connectivity, we investigated how focused attention and open monitoring meditation styles impact large-scale brain networks. Specifically, we trained a classifier to predict the meditation style in two groups of subjects: expert Theravada Buddhist monks and novice meditators. We showed that the classifier was able to discriminate the meditation style only in the expert group. Additionally, by inspecting the trained classifier, we observed that the Anterior Salience and the Default Mode networks were relevant for the classification, in line with their theorized involvement in emotion and self-related regulation in meditation. Interestingly, results also highlighted the role of specific couplings between areas crucial for regulating attention and self-awareness as well as areas related to processing and integrating somatosensory information. Finally, we observed a larger involvement of left inter-hemispheric connections in the classification. In conclusion, our work supports the evidence that extensive meditation practice modulates large-scale brain networks, and that the different meditation styles differentially affect connections that subserve style-specific functions.
Accessibility:	Document exists in file
Language:	eng
Author:	Guidotti, R.
Secondary author(s):	D'Andrea, A., Basti, A., Raffone, A., Pizzella, V., Marzetti, L.
Document type:	Article
Number of reproductions:	3
Reference:	Guidotti, R., D'Andrea, A., Basti, A., Raffone, A., Pizzella, V., & Marzetti, L. (2023). Long-term and meditation-specific modulations of brain connectivity revealed through multivariate pattern analysis. Brain Topography, 36(3), 409-418. https://doi.org/10.1007/s10548-023-00950-3
2-year Impact Factor:	2.3\|2023
Times cited:	8\|2025-02-18
Indexed document:	Yes
Quartile:	Q3
Keywords:	Functional magnetic resonance imaging (fMRI) / Functional connectivity / Machine learning / Focused attention mediation / Open monitoring meditation / Mindfulnes
Long-term and meditation-specific modulations of brain connectivity revealed through multivariate pattern analysis

Document

Mindfulness meditation styles differently modulate source-level MEG microstate dynamics and complexity

2024

BIAL Foundation Archive
- BIAL Grants
  - 2020 Grants
    - 080 - Mindfulness meditation state and trait through the eyes of brain computational modelling
      - Mindfulness meditation styles differently modulate source-level MEG microstate dynamics and complexity

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2020
Location:	BF-GMS
Title:	2020 Grants
Start date:	2021-01

Reference code:	PT/FB/BL-2020-080
Location:	BF-GMS
Title:	080 - Mindfulness meditation state and trait through the eyes of brain computational modelling
Duration:	2021-10
Researcher(s):	Laura Marzetti
Institution(s):	Department of Neurosciences, Imaging and Clinical Sciences, Università degli Studi "G. d'Annunzio" Chieti - Pescara (Italy)
Abstract/Results:	Contents: Application form Correspondence Research Funding Agreement Progress report Articles
Language:	eng
Notes:	Ongoing project
Author:	Marzetti, L.
Number of reproductions:	3
Keywords:	Meditation / Brain states / Computational modelling / Neuroimaging / Psychophysiology and Parapsychology

Reference code:	PT/FB/BL-2020-080.05
Location:	BF-GMS
Title:	Mindfulness meditation styles differently modulate source-level MEG microstate dynamics and complexity
Publication year:	2024
URL:	https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2024.1295615/full
Abstract/Results:	ABSTRACT: Background: The investigation of mindfulness meditation practice, classically divided into focused attention meditation (FAM), and open monitoring meditation (OMM) styles, has seen a long tradition of theoretical, affective, neurophysiological and clinical studies. In particular, the high temporal resolution of magnetoencephalography (MEG) or electroencephalography (EEG) has been exploited to fill the gap between the personal experience of meditation practice and its neural correlates. Mounting evidence, in fact, shows that human brain activity is highly dynamic, transiting between different brain states (microstates). In this study, we aimed at exploring MEG microstates at source-level during FAM, OMM and in the resting state, as well as the complexity and criticality of dynamic transitions between microstates. Methods: Ten right-handed Theravada Buddhist monks with a meditative expertise of minimum 2,265 h participated in the experiment. MEG data were acquired during a randomized block design task (6 min FAM, 6 min OMM, with each meditative block preceded and followed by 3 min resting state). Source reconstruction was performed using eLORETA on individual cortical space, and then parcellated according to the Human Connect Project atlas. Microstate analysis was then applied to parcel level signals in order to derive microstate topographies and indices. In addition, from microstate sequences, the Hurst exponent and the Lempel-Ziv complexity (LZC) were computed. Results: Our results show that the coverage and occurrence of specific microstates are modulated either by being in a meditative state or by performing a specific meditation style. Hurst exponent values in both meditation conditions are reduced with respect to the value observed during rest, LZC shows significant differences between OMM, FAM, and REST, with a progressive increase from REST to FAM to OMM. Discussion: Importantly, we report changes in brain criticality indices during meditation and between meditation styles, in line with a state-like effect of meditation on cognitive performance. In line with previous reports, we suggest that the change in cognitive state experienced in meditation is paralleled by a shift with respect to critical points in brain dynamics.
Accessibility:	Document exists in file
Language:	eng
Author:	D'Andrea, A.
Secondary author(s):	Croce, P., O'Byrne, J., Jerbi, K., Pascarella, A., Raffone, A., Pizzella, V., Marzetti, L.
Document type:	Article
Number of reproductions:	3
Reference:	D'Andrea, A., Croce, P., O'Byrne, J., Jerbi, K., Pascarella, A., Raffone, A., Pizzella, V., & Marzetti, L. (2024). Mindfulness meditation styles differently modulate source-level MEG microstate dynamics and complexity. Frontiers in Neuroscience, 18, 1295615. https://doi.org/10.3389/fnins.2024.1295615
2-year Impact Factor:	3.2\|2023
Impact factor notes:	Impact factor not available yet for 2024
Times cited:	0\|2025-02-19
Indexed document:	Yes
Quartile:	Q2
Keywords:	Microstate analysis / Brain criticality / Complexity / Mindfulness meditation / Open monitoring meditation / Focused attention meditation / Magnetoencephalography
Mindfulness meditation styles differently modulate source-level MEG microstate dynamics and complexity