Reference code: | PT/FB/BL-2020-146.03 |
Location: | BF-GMS
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Title:
| EEG resting state alpha dynamics predict an individual’s vulnerability to auditory hallucinations
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Publication year: | 2024
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URL:
| https://doi.org/10.1007/s11571-024-10093-1
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Abstract/Results: | ABSTRACT:
Task-free brain activity exhibits spontaneous fluctuations between functional states, characterized by synchronized activation patterns in distributed resting-state (RS) brain networks. The temporal dynamics of the networks’ electrophysiological signatures reflect individual variations in brain activity and connectivity linked to mental states and cognitive functions and can predict or monitor vulnerability to develop psychiatric or neurological disorders. In particular, RS alpha fluctuations modulate perceptual sensitivity, attentional shifts, and cognitive control, and could therefore reflect a neural correlate of increased vulnerability to sensory distortions, including the proneness to hallucinatory experiences. We recorded 5 min of RS EEG from 33 non-clinical individuals varying in hallucination proneness (HP) to investigate links between task-free alpha dynamics and vulnerability to hallucinations. To this end, we used a dynamic brain state allocation method to identify five recurrent alpha states together with their spatiotemporal dynamics and most active brain areas through source reconstruction. The dynamical features of a state marked by activation in somatosensory, auditory, and posterior default-mode network areas predicted auditory and auditory-verbal HP, but not general HP, such that individuals with higher vulnerability to auditory hallucinations spent more time in this state. The temporal dynamics of spontaneous alpha activity might reflect individual differences in attention to internally generated sensory events and altered auditory perceptual sensitivity. Altered RS alpha dynamics could therefore instantiate a neural marker of increased vulnerability to
auditory hallucinations.
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Accessibility: | Document exists in file
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Language:
| eng
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Author:
| Honcamp, H.
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Secondary author(s):
| Duggirala, S. X., Climent, J. R., Astudillo, A., Trujillo-Barreto, N. J., Schwartze, M., Linden, D. E. J., van Amelsvoort, T. A. M. J., El-Deredy, W., Kotz, S. A.
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Document type:
| Article
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Number of reproductions:
| 1
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Reference:
| Honcamp, H., Duggirala, S. X., Climent, J. R., Astudillo, A., Trujillo-Barreto, N. J., Schwartze, M., Linden, D. E. J., van Amelsvoort, T. A. M. J., El-Deredy, W., & Kotz, S. A. (2024). EEG resting state alpha dynamics predict an individual’s vulnerability to auditory hallucinations. Cognitive Neurodynamics. https://doi.org/10.1007/s11571-024-10093-1
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2-year Impact Factor: | 3.7|2022
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Impact factor notes: | Impact factor not available yet for 2024
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Times cited: | 0|2024-05-27
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Indexed document: | Yes
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Quartile: | Q2
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Keywords: | Alpha / EEG resting state / Hallucination proneness / Hidden semi-Markov modeling / Risk assessment / Temporal dynamics
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EEG resting state alpha dynamics predict an individual’s vulnerability to auditory hallucinations |