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File288 - The origin of the sublime power in the brain: An integrated EEG-TMS study2021-04

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-288
Location: BF-GMS
Title:
288 - The origin of the sublime power in the brain: An integrated EEG-TMS study
Duration: 2021-04
Researcher(s):
Eleonora Maggioni, Paolo Brambilla, Giandomenico Schiena, Alice Chirico, Andrea Gaggioli, Maddalena Mazzocut-Mis
Institution(s): Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan (Italy); Universitŕ Cattolica del Sacro Cuore, Milan (Italy); Universitŕ degli Studi di Milano (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Maggioni, E.
Secondary author(s):
Brambilla, P., Schiena, G., Chirico, A., Gaggioli, A., Mazzocut-Mis, M.
Number of reproductions:
3
Keywords:
Virtual reality / Sublime / Brain connectivity / EEG-TMS / Parapsychology and Psychophysiology
DocumentMachine learning methods to predict outcomes of pharmacological treatment in psychosis2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-288
Location: BF-GMS
Title:
288 - The origin of the sublime power in the brain: An integrated EEG-TMS study
Duration: 2021-04
Researcher(s):
Eleonora Maggioni, Paolo Brambilla, Giandomenico Schiena, Alice Chirico, Andrea Gaggioli, Maddalena Mazzocut-Mis
Institution(s): Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan (Italy); Universitŕ Cattolica del Sacro Cuore, Milan (Italy); Universitŕ degli Studi di Milano (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Maggioni, E.
Secondary author(s):
Brambilla, P., Schiena, G., Chirico, A., Gaggioli, A., Mazzocut-Mis, M.
Number of reproductions:
3
Keywords:
Virtual reality / Sublime / Brain connectivity / EEG-TMS / Parapsychology and Psychophysiology

Reference code: PT/FB/BL-2020-288.02
Location: BF-GMS
Title:
Machine learning methods to predict outcomes of pharmacological treatment in psychosis
Publication year: 2023
URL:
https://www.nature.com/articles/s41398-023-02371-z
Abstract/Results: ABSTRACT:
In recent years, machine learning (ML) has been a promising approach in the research of treatment outcome prediction in psychosis. In this study, we reviewed ML studies using different neuroimaging, neurophysiological, genetic, and clinical features to predict antipsychotic treatment outcomes in patients at different stages of schizophrenia. Literature available on PubMed until March 2022 was reviewed. Overall, 28 studies were included, among them 23 using a single-modality approach and 5 combining data from multiple modalities. The majority of included studies considered structural and functional neuroimaging biomarkers as predictive features used in ML models. Specifically, functional magnetic resonance imaging (fMRI) features contributed to antipsychotic treatment response prediction of psychosis with good accuracies. Additionally, several studies found that ML models based on clinical features might present adequate predictive ability. Importantly, by examining the additive effects of combining features, the predictive value might be improved by applying multimodal ML approaches. However, most of the included studies presented several limitations, such as small sample sizes and a lack of replication tests. Moreover, considerable clinical and analytical heterogeneity among included studies posed a challenge in synthesizing findings and generating robust overall conclusions. Despite the complexity and heterogeneity of methodology, prognostic features, clinical presentation, and treatment approaches, studies included in this review suggest that ML tools may have the potential to predict treatment outcomes of psychosis accurately. Future studies need to focus on refining feature characterization, validating prediction models, and evaluate their translation in real-world clinical practice.
Accessibility: Document exists in file
Language:
eng
Author:
Del Fabro, L.
Secondary author(s):
Bondi, E., Serio, F.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Del Fabro, L., Bondi, E., Serio, F., Maggioni, E., D'Agostino, A., & Brambilla, P. (2023). Machine learning methods to predict outcomes of pharmacological treatment in psychosis. Translational Psychiatry, 13, 75. https://doi.org/10.1038/s41398-023-02371-z
2-year Impact Factor: 6.800|2022
Impact factor notes: Impact factor not available yet for 2023
Times cited: 2|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Machine learning / Psychosis / Antipsychotic treatments / Review

Machine learning methods to predict outcomes of pharmacological treatment in psychosis

Machine learning methods to predict outcomes of pharmacological treatment in psychosis
DocumentEnvironmental effects on brain functional networks in a juvenile twin population2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-288
Location: BF-GMS
Title:
288 - The origin of the sublime power in the brain: An integrated EEG-TMS study
Duration: 2021-04
Researcher(s):
Eleonora Maggioni, Paolo Brambilla, Giandomenico Schiena, Alice Chirico, Andrea Gaggioli, Maddalena Mazzocut-Mis
Institution(s): Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan (Italy); Universitŕ Cattolica del Sacro Cuore, Milan (Italy); Universitŕ degli Studi di Milano (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Maggioni, E.
Secondary author(s):
Brambilla, P., Schiena, G., Chirico, A., Gaggioli, A., Mazzocut-Mis, M.
Number of reproductions:
3
Keywords:
Virtual reality / Sublime / Brain connectivity / EEG-TMS / Parapsychology and Psychophysiology

Reference code: PT/FB/BL-2020-288.03
Location: BF-GMS
Title:
Environmental effects on brain functional networks in a juvenile twin population
Publication year: 2023
URL:
https://www.nature.com/articles/s41598-023-30672-2
Abstract/Results: ABSTRACT:
The brain's intrinsic organization into large-scale functional networks, the resting state networks (RSN), shows complex inter-individual variability, consolidated during development. Nevertheless, the role of gene and environment on developmental brain functional connectivity (FC) remains largely unknown. Twin design represents an optimal platform to shed light on these effects acting on RSN characteristics. In this study, we applied statistical twin methods to resting-state functional magnetic resonance imaging (rs-fMRI) scans from 50 young twin pairs (aged 10-30 years) to preliminarily explore developmental determinants of brain FC. Multi-scale FC features were extracted and tested for applicability of classical ACE and ADE twin designs. Epistatic genetic effects were also assessed. In our sample, genetic and environmental effects on the brain functional connections largely varied between brain regions and FC features, showing good consistency at multiple spatial scales. Although we found selective contributions of common environment on temporo-occipital connections and of genetics on frontotemporal connections, the unique environment showed a predominant effect on FC link- and node-level features. Despite the lack of accurate genetic modeling, our preliminary results showed complex relationships between genes, environment, and functional brain connections during development. A predominant role of the unique environment on multi-scale RSN characteristics was suggested, which needs replications on independent samples. Future investigations should especially focus on nonadditive genetic effects, which remain largely unexplored.
Accessibility: Document exists in file
Language:
eng
Author:
Tassi, E.
Secondary author(s):
Maggioni, E., Mauri, M., Fagnani, C., Agarwal, N., Bianchi, A. M., Stazi, M. A., Nobile, M., Brambilla, P.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Tassi, E., Maggioni, E., Mauri, M., Fagnani, C., Agarwal, N., Bianchi, A. M., Stazi, M. A., Nobile, M., & Brambilla, P. (2023). Environmental effects on brain functional networks in a juvenile twin population. Scientific Reports, 13(1), 3921. https://doi.org/10.1038/s41598-023-30672-2
2-year Impact Factor: 4.600|2022
Impact factor notes: Impact factor not available yet for 2023
Times cited: 0|2024-02-16
Indexed document: Yes
Quartile: Q2
Keywords: Resting state networks / Brain functional connectivity / Twins

Environmental effects on brain functional networks in a juvenile twin population

Environmental effects on brain functional networks in a juvenile twin population
DocumentA systematic review on the potential use of machine learning to classify major depressive disorder from healthy controls using resting state fMRI measures2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-288
Location: BF-GMS
Title:
288 - The origin of the sublime power in the brain: An integrated EEG-TMS study
Duration: 2021-04
Researcher(s):
Eleonora Maggioni, Paolo Brambilla, Giandomenico Schiena, Alice Chirico, Andrea Gaggioli, Maddalena Mazzocut-Mis
Institution(s): Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan (Italy); Universitŕ Cattolica del Sacro Cuore, Milan (Italy); Universitŕ degli Studi di Milano (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Maggioni, E.
Secondary author(s):
Brambilla, P., Schiena, G., Chirico, A., Gaggioli, A., Mazzocut-Mis, M.
Number of reproductions:
3
Keywords:
Virtual reality / Sublime / Brain connectivity / EEG-TMS / Parapsychology and Psychophysiology

Reference code: PT/FB/BL-2020-288.04
Location: BF-GMS
Title:
A systematic review on the potential use of machine learning to classify major depressive disorder from healthy controls using resting state fMRI measures
Publication year: 2023
URL:
https://www.sciencedirect.com/science/article/pii/S0149763422004614
Abstract/Results: ABSTRACT:
Background
Major Depressive Disorder (MDD) is a psychiatric disorder characterized by functional brain deficits, as documented by resting-state functional magnetic resonance imaging (rs-fMRI) studies.
Aims
In recent years, some studies used machine learning (ML) approaches, based on rs-fMRI features, for classifying MDD from healthy controls (HC). In this context, this review aims to provide a comprehensive overview of the results of these studies.
Design
The studies research was performed on 3 online databases, examining English-written articles published before August 5, 2022, that performed a two-class ML classification using rs-fMRI features. The search resulted in 20 eligible studies.
Results
The reviewed studies showed good performance metrics, with better performance achieved when the dataset was restricted to a more homogeneous group in terms of disease severity. Regions within the default mode network, salience network, and central executive network were reported as the most important features in the classification algorithms.
Limitations
The small sample size together with the methodological and clinical heterogeneity limited the generalizability of the findings.
Conclusions
In conclusion, ML applied to rs-fMRI features can be a valid approach to classify MDD and HC subjects and to discover features that can be used for additional investigation of the pathophysiology of the disease.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Bondi, E.
Secondary author(s):
Maggioni, E., Brambilla, P., Delvecchio, G.
Document type:
Article
Number of reproductions:
1
Percentiles:
3
Reference:
Bondi, E., Maggioni, E., Brambilla, P., & Delvecchio, G. (2023). A systematic review on the potential use of machine learning to classify major depressive disorder from healthy controls using resting state fMRI measures. Neuroscience and Biobehavioral Reviews, 144, 104972. https://doi.org/10.1016/j.neubiorev.2022.104972
2-year Impact Factor: 8.200|2022
Impact factor notes: Impact factor not available yet for 2023
Times cited: 10|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Major depressive disorder / Resting state functional magnetic resonance imaging / Rs-fMRI / Machine learning / Classification
DocumentMultimodal Integration in Psychiatry: Clinical Potential and Challenges2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-288
Location: BF-GMS
Title:
288 - The origin of the sublime power in the brain: An integrated EEG-TMS study
Duration: 2021-04
Researcher(s):
Eleonora Maggioni, Paolo Brambilla, Giandomenico Schiena, Alice Chirico, Andrea Gaggioli, Maddalena Mazzocut-Mis
Institution(s): Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan (Italy); Universitŕ Cattolica del Sacro Cuore, Milan (Italy); Universitŕ degli Studi di Milano (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Maggioni, E.
Secondary author(s):
Brambilla, P., Schiena, G., Chirico, A., Gaggioli, A., Mazzocut-Mis, M.
Number of reproductions:
3
Keywords:
Virtual reality / Sublime / Brain connectivity / EEG-TMS / Parapsychology and Psychophysiology

Reference code: PT/FB/BL-2020-288.05
Location: BF-GMS
Title:
Multimodal Integration in Psychiatry: Clinical Potential and Challenges
Publication year: 2023
URL:
https://link.springer.com/protocol/10.1007/978-1-0716-3230-7_15
Abstract/Results: ABSTRACT:
The integration of complementary neuroimaging and neurosignaling modalities allows us to obtain a comprehensive view of the structural and functional brain properties and to extend the spatiotemporal domain investigated. In this chapter will explore the domains of multimodal integration that seem to be more relevant in the study of the cerebral bases of psychiatric disorders as an essential contribution to the construction of a personalized and broad-spectrum model of brain anatomy and function, useful in the early identification of risk or diagnostic profiles and in the planning of effective treatment strategies.
Accessibility: Document does not exist in file
Language:
eng
Author:
Maggioni, E.
Secondary author(s):
Piani, M. C., Bondi, E., Bianchi, A. M., Brambilla, P.
Document type:
Book chapter
Number of reproductions:
1
Reference:
Maggioni, E., Piani, M. C., Bondi, E., Bianchi, A. M., & Brambilla, P. (2023). Multimodal Integration in Psychiatry: Clinical Potential and Challenges. In: D. Stoyanov, B., Draganski, P., Brambilla, & C., Lamm (Eds), Computational Neuroscience. Neuromethods (Vol 199). Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3230-7_15
Indexed document: Yes
Keywords: Neuroimaging / Electrophysiology / MRI / Electroencephalogram (EEG) / Psychiatry
DocumentBrain volumes in alcohol use disorder: Do females and males differ? A whole-brain magnetic resonance imaging mega-analysis2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-288
Location: BF-GMS
Title:
288 - The origin of the sublime power in the brain: An integrated EEG-TMS study
Duration: 2021-04
Researcher(s):
Eleonora Maggioni, Paolo Brambilla, Giandomenico Schiena, Alice Chirico, Andrea Gaggioli, Maddalena Mazzocut-Mis
Institution(s): Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan (Italy); Universitŕ Cattolica del Sacro Cuore, Milan (Italy); Universitŕ degli Studi di Milano (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Maggioni, E.
Secondary author(s):
Brambilla, P., Schiena, G., Chirico, A., Gaggioli, A., Mazzocut-Mis, M.
Number of reproductions:
3
Keywords:
Virtual reality / Sublime / Brain connectivity / EEG-TMS / Parapsychology and Psychophysiology

Reference code: PT/FB/BL-2020-288.06
Location: BF-GMS
Title:
Brain volumes in alcohol use disorder: Do females and males differ? A whole-brain magnetic resonance imaging mega-analysis
Publication year: 2023
URL:
https://onlinelibrary.wiley.com/doi/10.1002/hbm.26404
Abstract/Results: ABSTRACT:
Emerging evidence suggests distinct neurobiological correlates of alcohol use disorder (AUD) between sexes, which however remain largely unexplored. This work from ENIGMA Addiction Working Group aimed to characterize the sex differences in gray matter (GM) and white matter (WM) correlates of AUD using a whole-brain, voxel-based, multi-tissue mega-analytic approach, thereby extending our recent surface-based region of interest findings on a nearly matching sample using a complementary methodological approach. T1-weighted magnetic resonance imaging (MRI) data from 653 people with AUD and 326 controls was analyzed using voxel-based morphometry. The effects of group, sex, group-by-sex, and substance use severity in AUD on brain volumes were assessed using General Linear Models. Individuals with AUD relative to controls had lower GM volume in striatal, thalamic, cerebellar, and widespread cortical clusters. Group-by-sex effects were found in cerebellar GM and WM volumes, which were more affected by AUD in females than males. Smaller group-by-sex effects were also found in frontotemporal WM tracts, which were more affected in AUD females, and in temporo-occipital and midcingulate GM volumes, which were more affected in AUD males. AUD females but not males showed a negative association between monthly drinks and precentral GM volume. Our results suggest that AUD is associated with both shared and distinct widespread effects on GM and WM volumes in females and males. This evidence advances our previous region of interest knowledge, supporting the usefulness of adopting an exploratory perspective and the need to include sex as a relevant moderator variable in AUD.
Accessibility: Document exists in file
Language:
eng
Author:
Maggioni, E.
Secondary author(s):
GaravanGaravan, Allen, N. B., Batalla, A., Bellani, M., Chye, Y., Cousijn, J., Goudriaan, A. E., Hester, R., Hutchison, K., Li, C. R., Martin-Santos, R., Momenan, R., Sinha, R., Schmaal, L., Solowij, N., Suo, C., van Holst, R. J., Veltman, D. J., Yücel, M., Thompson, P. M., Conrod, P., Mackey, S., Garavan, H., Brambilla, P., Lorenzetti, V.
Document type:
Article
Number of reproductions:
1
Percentiles:
6
Reference:
Maggioni, E., Rossetti, M. G., Allen, N. B., Batalla, A., Bellani, M., Chye, Y., Cousijn, J., Goudriaan, A. E., Hester, R., Hutchison, K., Li, C. R., Martin-Santos, R., Momenan, R., Sinha, R., Schmaal, L., Solowij, N., Suo, C., van Holst, R. J., Veltman, D. J., Yücel, M., … Lorenzetti, V. (2023). Brain volumes in alcohol use disorder: Do females and males differ? A whole-brain magnetic resonance imaging mega-analysis. Human Brain Mapping, 44(13), 4652-4666. https://doi.org/10.1002/hbm.26404
2-year Impact Factor: 4.8|2022
Impact factor notes: Impact factor not available yet for 2023
Times cited: 1|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Alcohol dependence / Alcohol use disorders / MRI / Sex / Voxel-based morphometry

Brain volumes in alcohol use disorder: Do females and males differ? A whole-brain magnetic resonance imaging mega-analysis

Brain volumes in alcohol use disorder: Do females and males differ? A whole-brain magnetic resonance imaging mega-analysis
DocumentThe mental simulation of state/psychological stimuli in anxiety disorders: A 3T fMRI study2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-288
Location: BF-GMS
Title:
288 - The origin of the sublime power in the brain: An integrated EEG-TMS study
Duration: 2021-04
Researcher(s):
Eleonora Maggioni, Paolo Brambilla, Giandomenico Schiena, Alice Chirico, Andrea Gaggioli, Maddalena Mazzocut-Mis
Institution(s): Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan (Italy); Universitŕ Cattolica del Sacro Cuore, Milan (Italy); Universitŕ degli Studi di Milano (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Language: eng
Author:
Maggioni, E.
Secondary author(s):
Brambilla, P., Schiena, G., Chirico, A., Gaggioli, A., Mazzocut-Mis, M.
Number of reproductions:
3
Keywords:
Virtual reality / Sublime / Brain connectivity / EEG-TMS / Parapsychology and Psychophysiology

Reference code: PT/FB/BL-2020-288.07
Location: BF-GMS
Title:
The mental simulation of state/psychological stimuli in anxiety disorders: A 3T fMRI study
Publication year: 2023
URL:
https://pubmed.ncbi.nlm.nih.gov/37852592/
Abstract/Results: ABSTRACT:
Mental imagery plays an important role in cognitive and emotional processes, therefore it might contribute to psychopathology in affective disorders. Distressive intrusive imagery is a core feature of anxiety disorders, but the underlying neurobiology remains unexplored. Here, we examined the functional brain mechanisms involved in state/psychological imagery in individuals with anxiety disorders. Functional Magnetic Resonance Imaging (fMRI) was used to assess the brain circuits involved in state/psychological (vs. action) imagery controlled by letter detection on the same stimuli in 33 individuals with anxiety disorders relative to 33 healthy controls. Patients were faster than controls in processing state/psychological stimuli and in general in the imagery task. We found that the left superior frontal gyrus was differentially activated by the state/psychological (vs. action) imagery (vs. letter detection) in the anxious individuals vs. healthy controls. We suggest that this area, which is involved in processing of state/psychological semantic information, appears deregulated during imagery in subjects with anxiety disorders. Our study provided the first evidence of both behavioral and brain functional alterations during imagery, highlighting a key role of the left superior frontal gyrus.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Tomasino, B.
Secondary author(s):
Maggioni, E., Piani, M. C., Bonivento, C., D'Agostini, S, Balestrieri, M., Brambilla, P.
Document type:
Article
Number of reproductions:
1
Percentiles:
7
Reference:
Tomasino, B., Maggioni, E., Piani, M. C., Bonivento, C., D'Agostini, S., Balestrieri, M., & Brambilla, P. (2023). The mental simulation of state/psychological stimuli in anxiety disorders: A 3T fMRI study. Journal of Affective Disorders, 345, 435–442. https://doi.org/10.1016/j.jad.2023.10.079
2-year Impact Factor: 6.6|2022
Impact factor notes: Impact factor not available yet for 2023
Times cited: 0|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Anxiety / Emotion / Imagery / State/psychological stimuli / Functional magnetic resonance imaging (fMRI)