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BIAL Foundation
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File102 - Identifying altered resting state connectivity dynamics as predictors of auditory verbal hallucinations (AVH)

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2022
Location: BF-GMS
Title:
2022 Grants
Start date: 2023-01

Reference code: PT/FB/BL-2022-102
Location: BF-GMS
Title:
102 - Identifying altered resting state connectivity dynamics as predictors of auditory verbal hallucinations (AVH)
Researcher(s): Sonja Kotz, Hanna Honcamp, Michael Schwartze, David Linden, Federico de Martino, Ana Pinheiro
Institution(s): Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University (The Netherlands)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Article
Language: eng
Author:
Kotz, S. A.
Secondary author(s):
Honcamp, H., Schwartze, M., Linden, D. E., De Martino, F., Pinheiro, A. P.
Number of reproductions:
1
Keywords:
Auditory verbal hallucinations / Resting state / Brain dynamics / Hidden semi-markov modeling / Psychophysiology
DocumentRevisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling2024

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2022
Location: BF-GMS
Title:
2022 Grants
Start date: 2023-01

Reference code: PT/FB/BL-2022-102
Location: BF-GMS
Title:
102 - Identifying altered resting state connectivity dynamics as predictors of auditory verbal hallucinations (AVH)
Researcher(s): Sonja Kotz, Hanna Honcamp, Michael Schwartze, David Linden, Federico de Martino, Ana Pinheiro
Institution(s): Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University (The Netherlands)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Article
Language: eng
Author:
Kotz, S. A.
Secondary author(s):
Honcamp, H., Schwartze, M., Linden, D. E., De Martino, F., Pinheiro, A. P.
Number of reproductions:
1
Keywords:
Auditory verbal hallucinations / Resting state / Brain dynamics / Hidden semi-markov modeling / Psychophysiology

Reference code: PT/FB/BL-2022-102.02
Location: BF-GMS
Title:
Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling
Publication year: 2024
URL:
https://doi.org/10.1016/j.jneumeth.2024.110138
Abstract/Results: Background: Resting state (RS) brain activity is inherently non-stationary. Hidden semi-Markov Models (HsMM) can characterize continuous RS data as a sequence of recurring and distinct brain states along with their spatiotemporal dynamics.
New method: Recent explorations suggest that HsMM state dynamics in the alpha frequency band link to auditory hallucination proneness (HP) in non-clinical individuals. The present study aimed to replicate these findings to elucidate robust neural correlates of hallucinatory vulnerability. Specifically, we aimed to investigate the reproducibility of HsMM states across different data sets and within-data set variants as well as the replicability of the association between alpha brain state dynamics and HP.
Results: We found that most brain states are reproducible in different data sets, confirming that the HsMM characterized robust and generalizable EEG RS dynamics on a sub-second timescale. Brain state topographies and temporal dynamics of different within-data set variants showed substantial similarities and were robust against reduced data length and number of electrodes. However, the association with HP was not directly reproducible across data sets. Comparison with existing methods: The HsMM optimally leverages the high temporal resolution of EEG data and overcomes time-domain restrictions of other state allocation methods.
Conclusion: The results indicate that the sensitivity of brain state dynamics to capture individual variability in HP may depend on the data recording characteristics and individual variability in RS cognition, such as mind wandering. Future studies should consider that the order in which eyes-open and eyes-closed RS data are acquired directly influences an individual’s attentional state and generation of spontaneous thoughts, and thereby might mediate the link to hallucinatory vulnerability.
Accessibility: Document exists in file
Language:
eng
Author:
Honcamp, H.
Secondary author(s):
Schwartze, M., Amorim, M., Linden, D., Pinheiro, A., Kotz, S.
Document type:
Article
Number of reproductions:
1
Reference:
Honcamp, H., Schwartze, M., Amorim, M., Linden, D., Pinheiro, A., & Kotz, S. (2024). Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling. Journal of Neuroscience Methods, 110138. https://doi.org/10.1016/j.jneumeth.2024.110138
2-year Impact Factor: 3|2022
Impact factor notes: Impact factor not available yet for 2024
Times cited: 0|2024-06-19
Indexed document: No
Quartile: Q3
Keywords: Hidden semi-markov model / Resting state / Alpha dynamics / Reproducibility / Hallucination proneness / Spontaneous thoughts

Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling

Revisiting alpha resting state dynamics underlying hallucinatory vulnerability: Insights from Hidden semi-Markov Modeling