Reference code: | PT/FB/BL-2022-106.02 |
Location: | BF-GMS
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Title:
| Gaze-centered gating, reactivation, and reevaluation of economic value in orbitofrontal cortex
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Publication year: | 2024
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URL:
| https://doi.org/10.1038/s41467-024-50214-2
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Abstract/Results: | ABSTRACT:
During economic choice, options are often considered in alternation, until commitment. Nonetheless, neuroeconomics typically ignores the dynamic aspects of deliberation. We trained two male macaques to perform a valuebased decision-making task in which two risky offers were presented in sequence at the opposite sides of the visual field, each followed by a delay epochwhere offerswere invisible. Surprisingly, during the two delays, subjects tend to look at empty locations where the offers had previously appeared, with longer fixations increasing the probability of choosing the associated offer. Spiking activity in orbitofrontal cortex reflects the value of the gazed offer, or of the offer associated with the gazed empty spatial location, even if it is not the most recent. This reactivation reflects a reevaluation process, as fluctuations in neural spiking correlate with upcoming choice. Our results suggest that look-at-nothing gazing triggers the reactivation of a previously seen offer for further evaluation.
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Accessibility: | Document exists in file
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Language:
| eng
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Author:
| Ferro, D.
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Secondary author(s):
| Cash-Padgett, T., Wang, M. Z., Hayden, B. Y., Moreno-Bote, R.
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Document type:
| Article
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Number of reproductions:
| 1
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Reference:
| Ferro, D., Cash-Padgett, T., Wang, M. Z., Hayden, B. Y., & Moreno-Bote, R. (2024). Gaze-centered gating, reactivation, and reevaluation of economic value in orbitofrontal cortex. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-50214-2
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2-year Impact Factor: | 14.7|2023
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Times cited: | 0|2024-07-26
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Indexed document: | Yes
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Quartile: | Q1
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Keywords: | Gaze-centered gating / Reactivation / Reevaluation / Orbitofrontal cortex
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Gaze-centered gating, reactivation, and reevaluation of economic value in orbitofrontal cortex |