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DocumentTrajectories of childhood internalizing and externalizing psychopathology and psychotic-like experiences in adolescence: A prospective population-based cohort study2016

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194
Location: Arquivo PCA - Pasta 25/2012
Title:
194 - Characterising developmental trajectories of brain function from childhood into adolescence
Duration: 2013-04 - 2017-09
Researcher(s):
Kristin Robin Laurens, Ruth E. Roberts
Institution(s): Department of Forensic and Neurodevelopmental Sciences,Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Roberts, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Biopsychological problems / Mental health / Psychotic disorders / Brain structure and function

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194.04
Location: Arquivo PCA - Pasta 25/2012
Title:
Trajectories of childhood internalizing and externalizing psychopathology and psychotic-like experiences in adolescence: A prospective population-based cohort study
Publication year: 2016
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855987/
Abstract/Results: ABSTRACT:
Adolescent internalizing and externalizing psychopathology is strongly associated with adult psychiatric morbidity, including psychotic disorders. This study examined whether internalizing or externalizing trajectories (continuity/discontinuity of symptoms) from middle childhood were associated with adolescent psychotic-like experiences (PLEs). Prospective data were collected from a community sample of 553 children (mean age = 10.4 years; 50% male) and their primary caregivers. Participants completed questionnaire reports of internalizing and externalizing psychopathology and PLEs at baseline, and again approximately 2 years later. Logistic regression was used to examine the association of adolescent PLEs with four trajectories of internalizing and externalizing psychopathology (persistent, incident, remitting, and none), controlling for a range of potential confounders and sampling bias. Significant associations were identified between adolescent PLEs and the incident internalizing (adjusted odds ratio [adj. OR] = 2.96; 95% confidence interval [CI] = 1.60–5.49) and externalizing psychopathology (adj. OR = 2.14; 95% CI = 1.11–4.14) trajectories, as well as the persistent internalizing (adj. OR = 1.90; 95% CI = 1.13–3.18) and externalizing (adj. OR = 1.81, 95% CI = 1.02–3.19) trajectories. Children with remitting psychopathology trajectories were no more likely to present later PLEs than those who never experienced psychopathology. While for many individuals symptoms and illness remit during development without intervention, this study provides important insights regarding potential targets and timing for delivery of early intervention and prevention programs.
Accessibility: Document exists in file
Language:
eng
Author:
Lancefield, K. S.
Secondary author(s):
Raudino, A., Downs, J. M., Laurens, K. R.
Document type:
Article
Number of reproductions:
1
Percentiles:
83.47|1.64
Reference:
Lancefield, K. S., Raudino, A., Downs, J. M., & Laurens, K. R. (2016). Trajectories of childhood internalizing and externalizing psychopathology and psychotic-like experiences in adolescence: A prospective population-based cohort study. Development and Psychopathology, 28(2), 527-536. https://doi.org/10.1017/S0954579415001108
Impact Factor: 3.244|2016
Times cited: 52|2026-02-08
Indexed document: Yes
Quartile: Q1
Keywords: Adolescence / Developmental psychopathology / High-risk / Psychosis / Psychotic-like experiences

<!-- mm occ=1 guid=[5efa587b030da59ff0d6bce83a82062a] WebBehavior$=[0] -->

Trajectories of childhood internalizing and externalizing psychopathology and psychotic-like experiences in adolescence: A prospective population-based cohort study

Trajectories of childhood internalizing and externalizing psychopathology and psychotic-like experiences in adolescence: A prospective population-based cohort study
DocumentTrajectories of cognitive development during adolescence among youth at-risk for schizophrenia2018

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194
Location: Arquivo PCA - Pasta 25/2012
Title:
194 - Characterising developmental trajectories of brain function from childhood into adolescence
Duration: 2013-04 - 2017-09
Researcher(s):
Kristin Robin Laurens, Ruth E. Roberts
Institution(s): Department of Forensic and Neurodevelopmental Sciences,Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Roberts, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Biopsychological problems / Mental health / Psychotic disorders / Brain structure and function

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194.11
Location: Arquivo PCA - Pasta 25/2012
Title:
Trajectories of cognitive development during adolescence among youth at-risk for schizophrenia
Publication year: 2018
URL:
https://onlinelibrary.wiley.com/doi/full/10.1111/jcpp.12912
Abstract/Results: ABSTRACT:
BACKGROUND:
Among adults with schizophrenia, evidence suggests that premorbid deficits in different cognitive domains follow distinct developmental courses during childhood and adolescence. The aim of this study was to delineate trajectories of adolescent cognitive functions prospectively among different groups of youth at-risk for schizophrenia, relative to their typically developing (TD) peers.
METHOD:
Using linear mixed models adjusted for sex, ethnicity, parental occupation and practice effects, cognitive development between ages 9 and 16 years was compared for youth characterised by a triad of well-replicated developmental antecedents of schizophrenia (ASz; N = 32) and youth with a least one affected relative with schizophrenia or schizoaffective disorder (FHx; N = 29), relative to TD youth (N = 45). Participants completed measures of IQ, scholastic achievement, memory and executive function at three time-points, separated by approximately 24-month intervals.
RESULTS:
Compared to TD youth, both ASz and FHx youth displayed stable developmental deficits in verbal working memory and inhibition/switching executive functions. ASz youth additionally presented with stable deficits in measures of vocabulary (IQ), word reading, numerical operations, and category fluency executive function, and a slower rate of growth (developmental lag) on spelling from 9 to 16 years than TD peers. Conversely, faster rates of growth relative to TD peers (developmental delay) were observed on visual and verbal memory, and on category fluency executive function (ASz youth only) and on matrix reasoning (IQ) and word reading (FHx youth only).
CONCLUSIONS:
These differential patterns of deviation from normative adolescent cognitive development among at-risk youth imply potential for cognitive rehabilitation targeting of specific cognitive deficits at different developmental phases.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Dickson, H.
Secondary author(s):
Cullen, A. E., Jones, R., Reichenberg, A., Roberts, R. E., Hodgins, S., Morris, R. G., Laurens, K. R.
Document type:
Article
Number of reproductions:
1
Percentiles:
75.26|1.09
Reference:
Dickson, H., Cullen, A. E., Jones, R., Reichenberg, A., Roberts, R. E., Hodgins, S., Morris, R. G., & Laurens, K. R. (2018). Trajectories of cognitive development during adolescence among youth at-risk for schizophrenia. Journal of Child Psychology and Psychiatry, 59(11), 1215-1224. https://doi.org/10.1111/jcpp.12912
Impact Factor: 3.593|2018
Times cited: 25|2026-02-11
Indexed document: Yes
Quartile: Q1
Keywords: Psychosis / Academic performance / Executive function / Intelligence / Memory

<!-- mm occ=1 guid=[80282f86f6b149aff3e61230da514c72] WebBehavior$=[3] -->
DocumentAdolescent trajectories of cognition and risk for psychosis2016

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194
Location: Arquivo PCA - Pasta 25/2012
Title:
194 - Characterising developmental trajectories of brain function from childhood into adolescence
Duration: 2013-04 - 2017-09
Researcher(s):
Kristin Robin Laurens, Ruth E. Roberts
Institution(s): Department of Forensic and Neurodevelopmental Sciences,Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Roberts, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Biopsychological problems / Mental health / Psychotic disorders / Brain structure and function

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194.05
Location: Arquivo PCA - Pasta 25/2012
Title:
Adolescent trajectories of cognition and risk for psychosis
Publication year: 2016
URL:
http://www.nature.com/public/article-assets/npg/npjschz/abstracts/npjschz201610.pdf
Abstract/Results: ABSTRACT:
BACKGROUND
Impairments in multiple cognitive domains are apparent among youth who later develop schizophrenia, but it has been hypothesized that different impairments might follow distinct developmental courses from childhood into adolescence. The aim of the study was to examine developmental trajectories of cognitive growth during adolescence in youth at-risk for psychosis.
METHODS
104 participants were assessed at approximately 24-month intervals (time 1, aged 9-12 years; time 2, 11-14 years; and time 3,
13-17 years) on measures of scholastic achievement, memory, and executive function. Cognitive development between ages 9-17 years was compared between youth characterized by a triad of wellreplicated developmental antecedents of schizophrenia (ASz, N = 32); youth with a least one affected relative with schizophrenia or schizoaffective disorder (FHx; N = 29); and typically developing youth (TD, N = 45).
RESULTS
longitudinal mixed models for repeated measures data indicated that, between the ages of 9-17 years, ASz and FHx groups (relative to TD youth) displayed static impairments on word reading, numerical operations, verbal working memory, visual memory and some aspects of executive functioning, but dynamically changing patterns of cognitive growth on spelling, verbal memory and verbal fluency subtests.
DISCUSSION
The present study identified two important patterns of cognitive growth among youth at-risk for psychosis that have also been observed premorbidly among individuals with schizophrenia. The stable cognitive deficits observed in this study may represent
more suitable targets for cognitive training interventions than dynamically changing patterns of cognitive growth that appear to reflect developmental plasticity and recuperation.
Accessibility: Document exists in file
Language:
eng
Author:
Dickson, H.
Secondary author(s):
Cullen, A. E., Jones, R., Reichenberg, A., Roberts, R. E., Hodgins, S., Morris, R. M., Laurens, K. R.
Document type:
Abstract
Number of reproductions:
1
Reference:
Dickson, H., Cullen, A. E., Jones, R., Reichenberg, A., Roberts, R. E., Hodgins, S., Morris, R. M., & Laurens, K. R. (2016). Adolescent trajectories of cognition and risk for psychosis. Poster presentation at the 5th Biennial Schizophrenia International Research Society Conference, Florence, Italy. npj Schizophrenia 2, Article number: 16007, 15. https://doi.org/10.1038/npjschz.2016.7
Indexed document: No
Keywords: Developmental psychopathology / Adolescence / High-risk / Psychosis / Cognitive impairments

<!-- mm occ=1 guid=[230209f05d642aa5e851100e9d45c3b3] WebBehavior$=[0] -->

Adolescent trajectories of cognition and risk for psychosis

Adolescent trajectories of cognition and risk for psychosis
DocumentAdolescent trajectories of motor function and risk for psychosis2016

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194
Location: Arquivo PCA - Pasta 25/2012
Title:
194 - Characterising developmental trajectories of brain function from childhood into adolescence
Duration: 2013-04 - 2017-09
Researcher(s):
Kristin Robin Laurens, Ruth E. Roberts
Institution(s): Department of Forensic and Neurodevelopmental Sciences,Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Roberts, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Biopsychological problems / Mental health / Psychotic disorders / Brain structure and function

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194.06
Location: Arquivo PCA - Pasta 25/2012
Title:
Adolescent trajectories of motor function and risk for psychosis
Publication year: 2016
URL:
http://www.nature.com/public/article-assets/npg/npjschz/abstracts/npjschz20168.pdf
Abstract/Results: ABSTRACT:
BACKGROUND
Evidence indicates that individuals who subsequently develop schizophrenia/ schizophrenia spectrum disorders (SDD) in adulthood display poorer motor function during early and middle childhood than individuals who do not develop these disorders.
However, among individuals who develop schizophrenia/SSD in adulthood, motor dysfunction is not apparent at all stages of childhood development and may reduce with increasing age. Currently, little is known about the developmental trajectories of motor function in adolescence among youth at-risk for the disorder.
METHODS
94 participants were assessed at approximately 24-month intervals (time 1, aged 9-12 years; time 2, 11-14 years; and time 3, 13-17 years) on the Purdue Pegboard assessment, comprising four subtests: dominant hand, non-dominant hand, both hands, assembly subtest. Motor function between ages 9-16 years was compared between youth characterized by a triad of well-replicated developmental antecedents of schizophrenia (ASz, N = 29); youth with a least one affected relative with schizophrenia or schizoaffective disorder (FHx; N = 26); and typically developing youth (TD, N = 42).
RESULTS
Longitudinal mixed models for repeated measures data indicated significant improvements with age in TD youth on the assembly subtest only. Relative to TD youth, FHx children exhibited an early deficit on the dominant hand and both hand subtests which was followed by faster rates of improvement with age, but a stable impairment on the assembly subtest across adolescence. In contrast, compared to the TD group, ASz youth showed an early deficit followed by significant improvements for the assembly subtest, but a stable impairment on the dominant hand and both hand subtests across adolescence.
DISCUSSION
Findings are consistent with existing literature indicating that risk for schizophrenia/SSD is associated with delayed motor development. The motor dysfunction observed in both at-risk groups may reflect cerebellar dysfunction, and provides additional support for a cognitive dysmetria model of schizophrenia.
Accessibility: Document exists in file
Language:
eng
Author:
Dickson, H.
Secondary author(s):
Roberts, R. E., To, M., Loh, M., Hodgins, S., Laurens, K. R.
Document type:
Abstract
Number of reproductions:
1
Reference:
Dickson, H., Roberts, R. E., To, M., Loh, M., Hodgins, S., & Laurens, K. R. (2016). Adolescent trajectories of motor function and risk for psychosis. Poster presentation at the 5th Biennial Schizophrenia International Research Society Conference, Florence, Italy. npj Schizophrenia 2, Article number: 16008, 15. https://doi.org/10.1038/npjschz.2016.8
Indexed document: No
Keywords: Motor function / Developmental psychopathology / High-risk / Psychosis / Adolescence

<!-- mm occ=1 guid=[81388b1c6db13ec3cc81cfb3caa87369] WebBehavior$=[0] -->

Adolescent trajectories of motor function and risk for psychosis

Adolescent trajectories of motor function and risk for psychosis
DocumentMapping development of the MMN and P3a potentials during adolescence: A longitudinal investigation of healthy individuals and individuals at-risk for psychosis2015

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194
Location: Arquivo PCA - Pasta 25/2012
Title:
194 - Characterising developmental trajectories of brain function from childhood into adolescence
Duration: 2013-04 - 2017-09
Researcher(s):
Kristin Robin Laurens, Ruth E. Roberts
Institution(s): Department of Forensic and Neurodevelopmental Sciences,Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Roberts, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Biopsychological problems / Mental health / Psychotic disorders / Brain structure and function

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194.07
Location: Arquivo PCA - Pasta 25/2012
Title:
Mapping development of the MMN and P3a potentials during adolescence: A longitudinal investigation of healthy individuals and individuals at-risk for psychosis
Publication year: 2015
URL:
http://www.frontiersin.org/10.3389/conf.fnhum.2015.217.00267/1692/XII_International_Conference_on_Cognitive_Neuroscience_(ICON-XII)/all_events/event_abstract
Abstract/Results: ABSTRACT:
Adolescence marks a period of transition from childhood to adulthood that is characterised by major changes in brain structure and function, and increased vulnerability to psychiatric disorder, including psychosis. Characterising normative developmental trajectories of brain function establishes an important baseline against which to map mechanisms contributing to pathological development. Cross-sectional investigations measuring the mismatch negativity (MMN) and P3a event-related potential components in healthy children and young adults have typically inferred increasing amplitudes and decreasing latencies during adolescence, interpreted as improved efficiency of sensory and cognitive processing. We sought to characterise within-individual trajectories of brain function in adolescence using a longitudinal design incorporating up to three assessments from late childhood though adolescence. Using a duration deviant passive auditory oddball paradigm, MMN and P3a components were recorded from 49 healthy children at approximately 24-month intervals (spanning ages 9-17 years). Linear mixed models, accounting for repeated measures, examined MMN and P3a amplitude and latency data from electrode FCz. Children at early pubertal stages had smaller MMN amplitude than adolescents in later pubertal stages, whereas MMN latency did not change with age or pubertal status. Random intercept models revealed a significant linear increase in P3a amplitude with age, while P3a latency increased initially from 11 years and stabilised by around 15 years. Longitudinal data analysis in children at-risk for psychosis is being finalised, with the aim of identifying the age(s) at which developmental trajectories of these components begin to diverge from the norm, and the nature of these deviations (e.g., delay vs. arrest of development).
Accessibility: Document does not exist in file
Language:
eng
Author:
Laurens, K. R.
Secondary author(s):
Murphy, J., Dickson, H., Roberts, R.
Document type:
Abstract
Number of reproductions:
1
Reference:
Laurens, K., Murphy, J., Dickson, H., & Roberts, R. (2015). Mapping development of the MMN and P3a potentials during adolescence: A longitudinal investigation of healthy individuals and individuals at-risk for psychosis. Frontiers Human Neuroscience. Conference Abstract: XII International Conference on Cognitive Neuroscience (ICON-XII). https://doi.org/10.3389/conf.fnhum.2015.217.00267
Indexed document: Yes
Keywords: Attention / Psychosis / ERP / Developmental psychopathology / Child and adolescent developmen
DocumentNeurophysiological correlates of excitement in men with recent-onset psychosis2018

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2002-090
Location: Arquivo PCA - Pasta 5/2002
Title:
090 - Brain function, creativity, paranormal ideation and risk for psychosis
Duration: 2003-03 - 2005-04
Researcher(s):
Alexander Sumich, Michael Brammer, Dominic Ffytch
Institution(s): Brain Image Analysis Unit, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Diskette (Reseacrch Bursary 02-03, Alex Sumich: Brain function, creativity, paranormal ideation and risk for psychosis - BIAL)
Language: eng
Author:
Sumich, A.
Secondary author(s):
Brammer, M., Ffytch, D.
Number of reproductions:
1
Keywords:
Psychophysiology / Brain structure and function / Biopsychological problems / Mental health / Psychotic disorders

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2002-090.07
Location: Arquivo PCA - Pasta 5/2002
Title:
Neurophysiological correlates of excitement in men with recent-onset psychosis
Publication year: 2018
URL:
http://www.psychiatria-danubina.com/UserDocsImages/pdf/dnb_vol30_no1/dnb_vol30_no1_64.pdf
Abstract/Results: ABSTRACT:
OBJECTIVE:
Right frontal function, as indicated by the N200 component of the event-related potential during target detection, has previously been associated with excitement (excitement, impulsivity, hostility, uncooperativeness) in men with a long-term diagnosis of schizophrenia. The current study investigated excitement in relation to N200 in men who had recently experienced their first episode of psychosis.
SUBJECTS AND METHODS:
Twenty men who had recently suffered their first psychotic episode underwent a clinical interview and auditory oddball task.
RESULTS:
Multiple linear regression analysis showed that 58% of the variance in the excitement symptom cluster was explained by a positive association with frontal midline N200 amplitude and an inverse association with right frontal N200 amplitude. The latter was not apparent in the initial correlation, suggesting suppression by the midline activity. These associations were not explained by drug use, medication or negative symptoms. However, the correlation between excitement and midline N200 was stronger in drug users, and that between right frontal N200 and excitement was stronger in nonusers.
CONCLUSION:
Findings support the independent contributions to excitement of mechanisms reflected in midline and right frontal N200 amplitude respectively during the early stages of psychosis.
Accessibility: Document exists in file
Language:
eng
Author:
Sumich, A.
Secondary author(s):
Harris, A., Whitford, T., Hermens, D., Heym, N., Anderson, J., Bloxsom, C., Kibowski, F., Kumari, V.
Document type:
Article
Number of reproductions:
1
Percentiles:
9.50|0.08
Reference:
Sumich, A., Harris, A., Whitford, T., Hermens, D., Heym, N., ..., Kumari, V. (2018). Neurophysiological correlates of excitement in men with recent-onset psychosis. Psychiatria Danubina, 30(1), 64-71. https://doi.org/10.24869/psyd.2018.64
Impact Factor: 0.683|2018
Times cited: 2|2026-02-11
Indexed document: Yes
Quartile: Q4
Keywords: Psychosis / Recent-onset / Event-related potentials / N200 / Excitement / Drug use

<!-- mm occ=1 guid=[b8906ee12f50ef0e5beba8874e7670e1] WebBehavior$=[0] -->

Neurophysiological correlates of excitement in men with recent-onset psychosis

Neurophysiological correlates of excitement in men with recent-onset psychosis
DocumentReliability and normative data of the perceptual aberration scale in an Italian juvenile general population sample2015

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-262
Location: Arquivo PCA - Pasta 29/2012
Title:
262 - The neural basis of Magical Ideation: A multimodal imaging study in twin subjects
Duration: 2013-08 - 2019-07
Researcher(s):
Paolo Brambilla, Gioia Negri, Sara Piccin, Giuseppe Cabras, Corrado Fagnani
Institution(s): Universitá delgi Studi di Milano and Unit of Epidemiology of the Italian Institute of Health, Rome (Italy)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Articles
Language: eng
Author:
Brambilla, P.
Secondary author(s):
Negri, G., Piccin, S., Cabras, G., Fagnani, C.
Number of reproductions:
3
Keywords:
Psychophysiology and Parapsychology / Paranormal belief / Brain structure and function / Personality

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-262.12
Location: Arquivo PCA - Pasta 29/2012
Title:
Reliability and normative data of the perceptual aberration scale in an Italian juvenile general population sample
Publication year: 2015
URL:
http://www.psy-journal.com/article/S0165-1781(15)00351-0/fulltext
Abstract/Results: ABSTRACT:
Psychometric tools, such as the Perceptual Aberration Scale (PAS), have been developed to identify people at risk to develop psychosis. This paper aims at providing an Italian version of the Perceptual Aberration Scale and its normative data for the general juvenile Italian population. The Italian version of the PAS was produced using three independent translators. It was administered to 1089 non-clinical participants, stratified into three age-groups, i.e., 8-13, 14-17 and 18-24. The Italian version of the PAS displayed good internal consistency in each age-group evaluated (i.e. Alpha Coefficients: 0.90 for the 8-13 age-group, 0.84 for the 14-17 age-group, and 0.87 for the 18-24 age-group) and the assumption of unidimensionality was corraborate. Furthermore, normative data for the three groups were collected (i.e. cut-offs: 25 for the 8-13 age-group, 21 for the 14-17 age-group and 20 for the 18-24 age-group) and an age-related difference, as the 18-24 group scored lower than the younger groups, was found. The Italian version of the PAS proved to be a reliable psychometric tool to investigate perceptual aberration during childhood, adolescence and young adulthood.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Fornasari, L.
Secondary author(s):
Picardi, A., Garzitto, M., Gigantesco, A., Sala, M., Romanò, M., Fabbro, F., Brambilla, P.
Document type:
Article
Number of reproductions:
3
Percentiles:
26.58|0.24
Reference:
Fornasari, L., Picardi, A., Garzitto, M., Gigantesco, A., Sala, M., Romanò, M., Fabbro, F., & Brambilla, P. (2015). Reliability and normative data of the perceptual aberration scale in an Italian juvenile general population sample. Psychiatry Research, 228(3), 495-500. https://doi.org/10.1016/j.psychres.2015.05.058
Impact Factor: 2.466|2015
Times cited: 8|2026-02-08
Indexed document: Yes
Quartile: Q2
Keywords: Psychosis / Assessment / Validity / Reliability / Prevention

<!-- mm occ=1 guid=[44fe52db4bc1081aac97b7f3d1a94fa5] WebBehavior$=[3] -->
DocumentApplying neuroimaging to detect neuroanatomical dysconnectivity in psychosis2015

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-262
Location: Arquivo PCA - Pasta 29/2012
Title:
262 - The neural basis of Magical Ideation: A multimodal imaging study in twin subjects
Duration: 2013-08 - 2019-07
Researcher(s):
Paolo Brambilla, Gioia Negri, Sara Piccin, Giuseppe Cabras, Corrado Fagnani
Institution(s): Universitá delgi Studi di Milano and Unit of Epidemiology of the Italian Institute of Health, Rome (Italy)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Articles
Language: eng
Author:
Brambilla, P.
Secondary author(s):
Negri, G., Piccin, S., Cabras, G., Fagnani, C.
Number of reproductions:
3
Keywords:
Psychophysiology and Parapsychology / Paranormal belief / Brain structure and function / Personality

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-262.15
Location: Arquivo PCA - Pasta 29/2012
Title:
Applying neuroimaging to detect neuroanatomical dysconnectivity in psychosis
Publication year: 2015
URL:
https://www.cambridge.org/core/journals/epidemiology-and-psychiatric-sciences/article/applying-neuroimaging-to-detect-neuroanatomical-dysconnectivity-in-psychosis/2421351FD3CAFF7BF6C3CD84D19779F0
Abstract/Results: ABSTRACT:
This editorial discusses the application of a novel brain imaging analysis technique in the assessment of neuroanatomical dysconnectivity in psychotic illnesses. There has long been a clinical interest in psychosis as a disconnection syndrome. In recent years graph theory metrics have been applied to functional and structural imaging datasets to derive measures of brain connectivity, which represent the efficiency of brain networks. These metrics can be derived from structural neuroimaging datasets acquired using diffusion imaging whereby cortical structures are parcellated into nodes and white matter tracts represent edges connecting these nodes. Furthermore neuroanatomical measures of connectivity may be decoupled from measures of physiological connectivity as assessed using functional imaging, underpinning the need for multi-modal imaging approaches to probe brain networks. Studies to date have reported a number of structural brain connectivity abnormalities associated with schizophrenia that carry potential as illness biomarkers. Structural connectivity abnormalities have also been reported in well patients with bipolar disorder and in unaffected relatives of patients with schizophrenia. Such connectivity metrics may represent clinically relevant biomarkers in studies employing a longitudinal design of illness course in psychosis.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
O'Donoghue, S.
Secondary author(s):
Cannon, D. M., Perlini, C., Brambilla, P., McDonald, C.
Document type:
Article
Number of reproductions:
3
Percentiles:
84.73|1.41
Reference:
O'Donoghue, S., Cannon, D. M., Perlini, C., Brambilla, P., & McDonald, C. (2015). Applying neuroimaging to detect neuroanatomical dysconnectivity in psychosis. Epidemiology and Psychiatric Sciences, 24, 298-302. https://doi.org/10.1017/S2045796015000074
Impact Factor: 2.847|2015
Times cited: 12|2026-02-08
Indexed document: Yes
Quartile: Q2
Keywords: Brain imaging techniques / Psychosis / Schizophrenia / structural magnetic resonance imaging

<!-- mm occ=1 guid=[e85b5728c7fb01fbcce32ef6df4aedb4] WebBehavior$=[3] -->
DocumentFinal report - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks2019

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016-195
Location: BF-GMS
Title:
195 - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks
Duration: 2017-04 - 2019-10
Researcher(s):
Sjoerd Ebisch, Mauro Gianni Perrucci
Institution(s): Department of Neurosciences, Imaging and Clinical Sciences, University "G. D'Annunzio" of Chieti - Pescara (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Ebisch, S.
Secondary author(s):
Perrucci, M. G.
Number of reproductions:
1
Keywords:
Intrinsic self / Extrinsic self / Brain network interactions / Neuroimaging / Psychophysiology

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016-195.01
Location: BF-GMS
Title:
Final report - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks
Publication year: 2019
Abstract/Results:
ABSTRACT
BACKGROUND
It is poorly understood how the brain integrates intrinsic and extrinsic self-concepts to constitute a sense of self. It was hypothesized that the dynamic integration/segregation of functional brain networks could support a sense of self.
AIMS
To investigate how intrinsic and extrinsic self-processes and related brain networks interact to constitute a sense of self, and its association with traits of altered self-experience.
METHOD
Behavioral and fMRI data were obtained from 39 healthy participants to provide measures of implicit intrinsic and extrinsic self-processing, and of individual psychosis-relevant traits. Using graph theoretical measures of brain functional connectivity (FC), modularity and participation indices were calculated. It was tested how FC measures (i) were modulated by different levels of intrinsic and extrinsic self-relatedness induced by the fMRI task; (ii) were associated with behavioral measures of the sense of self; (iii) were associated with psychosis-relevant traits.
RESULTS
The results show that a functional integration of multiple brain subsystems (sensorimotor, default mode, memory, cognitive control, higher order cognition) supports both intrinsic and extrinsic self-processing. Increased levels of individual psychosis-like experiences were associated with the loss of hubness/decreased cross-network interactions when self-relatedness on multiple dimensions is incongruent.
CONCLUSIONS
The dynamic integration/segregation of brain networks involved in intrinsic and extrinsic self-processing supports a multidimensional sense of self. Higher levels of psychosis-relevant traits could be associated with diminished cross-network interactions, especially in situations of ambiguous self-relatedness.
Accessibility: Document exists in file
Language:
eng
Author:
Ebisch, S.
Secondary author(s):
Perrucci, M. G., Di Plinio, S.
Document type:
Final report
Number of reproductions:
1
Reference:
Ebisch, S., Perrucci, M. G., & Di Plinio, S. (2019). Final report - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks.
Indexed document: No
Keywords: Intrinsic self / Extrinsic self / Psychosis / Brain networks / fMRI

<!-- mm occ=1 guid=[aae526dc7061717c638163286eed6dcc] WebBehavior$=[0] -->

Final report - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks

Final report - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks
DocumentEnvironmental control and psychosis-relevant traits modulate the prospective sense of agency in non-clinical individuals2019

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016-195
Location: BF-GMS
Title:
195 - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks
Duration: 2017-04 - 2019-10
Researcher(s):
Sjoerd Ebisch, Mauro Gianni Perrucci
Institution(s): Department of Neurosciences, Imaging and Clinical Sciences, University "G. D'Annunzio" of Chieti - Pescara (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Ebisch, S.
Secondary author(s):
Perrucci, M. G.
Number of reproductions:
1
Keywords:
Intrinsic self / Extrinsic self / Brain network interactions / Neuroimaging / Psychophysiology

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016-195.03
Location: BF-GMS
Title:
Environmental control and psychosis-relevant traits modulate the prospective sense of agency in non-clinical individuals
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/pii/S1053810019301187?via%3Dihub
Abstract/Results: ABSTRACT:
The sense of agency concerns the experience of being the source of one's own actions and their consequences. An altered sense of agency can occur due to task automation and in psychosis. We tested in a non-clinical sample the hypothesis that reducing voluntary task control diminishes intentional binding as an implicit indicator of the sense of agency, possibly interacting with psychosis-relevant personality traits. Agent-device interactions were manipulated obtaining positive-control (voluntary interaction), no-control (automation), and negative-control (device-commanded interaction) groups. The main results showed reduced prospective intentional binding (predictive coding of action consequences) in the no-control and negative-control groups, compared to the positive-control group. Psychosis-like experiences covaried positively with intentional binding in the no-control group, but negatively in the negative-control group. Moreover, positive-social traits were associated with increased intentional binding in the positive-control group. These findings demonstrate the interplay between environmental and individual differences variables in establishing the implicit sense of agency.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Di Plinio, S.
Secondary author(s):
Arnò, S., Perrucci, M. G., Ebisch, S. J. H.
Document type:
Article
Number of reproductions:
1
Percentiles:
64.93|0.87
Reference:
Di Plinio, S., Arnò, S., Perrucci, M. G., & Ebisch, S. J. (2019). Environmental control and psychosis-relevant traits modulate the prospective sense of agency in non-clinical individuals. Consciousness and Cognition, 73: 102776. https://doi.org/10.1016/j.concog.2019.102776
Impact Factor: 2.044|2019
Times cited: 19|2026-02-11
Indexed document: Yes
Quartile: Q2
Keywords: Automation / Automatizing / Device-controlled environment / Environmental control / Intentional binding / Motor intention / Predictive / Prospective / Psychosis / Schizotypal / Sense of agency / Social

<!-- mm occ=1 guid=[b01ecc078f70b97b88bff39b509aa1db] WebBehavior$=[3] -->
DocumentI am Me: Brain systems integrate and segregate to establish a multidimensional sense of self2019

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016-195
Location: BF-GMS
Title:
195 - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks
Duration: 2017-04 - 2019-10
Researcher(s):
Sjoerd Ebisch, Mauro Gianni Perrucci
Institution(s): Department of Neurosciences, Imaging and Clinical Sciences, University "G. D'Annunzio" of Chieti - Pescara (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Ebisch, S.
Secondary author(s):
Perrucci, M. G.
Number of reproductions:
1
Keywords:
Intrinsic self / Extrinsic self / Brain network interactions / Neuroimaging / Psychophysiology

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016-195.04
Location: BF-GMS
Title:
I am Me: Brain systems integrate and segregate to establish a multidimensional sense of self
Publication year: 2019
URL:
https://www.sciencedirect.com/science/article/abs/pii/S1053811919308754?via%3Dihub
Abstract/Results: ABSTRACT:
Humans experience a sense of self, which is proposed to emerge from the integration of intrinsic and extrinsic self-processing through the propagation of information across brain systems. Using a novel functional magnetic resonance imaging (fMRI) paradigm, we tested this hypothesis in a non-clinical sample by modulating the intrinsic and extrinsic self-relatedness of auditory action consequences in terms of identity and agency, respectively. In addition, the relevance of individual traits associated with altered self-experiences (e.g., psychosis-like experiences) was examined. The task-evoked fMRI results showed distinctive associations between the neural coding of identity and negative affect traits, and between agency and psychosis-like experiences. Most importantly, regarding the functional connectivity analysis, graph theoretical measures demonstrated that the simultaneous processing of identity and agency relies on the functional integration and segregation of default mode, sensorimotor, language, and executive brain networks. Finally, cross-network interactions mediated by executive and sensorimotor regions were negatively associated with psychosis-like experiences when the intrinsic and extrinsic self-relatedness of action consequences conflicted. These findings provide evidence that the self is a multidimensional phenomenon rooted in the functional interactions between large-scale neuronal networks. Such interactions may have particular relevance for self-experience alterations.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Di Plinio, S.
Secondary author(s):
Perrucci, M. G., Aleman, A., Ebisch, S. J. H.
Document type:
Article
Number of reproductions:
1
Percentiles:
82.89|1.32
Reference:
Di Plinio, S., Perrucci, M. G., Aleman, A., & Ebisch, S. J. H. (2019). I am Me: Brain systems integrate and segregate to establish a multidimensional sense of self. NeuroImage, 205, Article 116284. https://doi.org/10.1016/j.neuroimage.2019.116284
Impact Factor: 5.902|2019
Times cited: 28|2026-02-11
Indexed document: Yes
Quartile: Q1
Keywords: Agency / Identity / Modularity / Psychosis / Self-relatedness

<!-- mm occ=1 guid=[80b0ba4c9c24900eb8de2fc168286a4a] WebBehavior$=[3] -->
DocumentAdolescent trajectories of fine motor and coordination skills and risk for schizophrenia2020

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194
Location: Arquivo PCA - Pasta 25/2012
Title:
194 - Characterising developmental trajectories of brain function from childhood into adolescence
Duration: 2013-04 - 2017-09
Researcher(s):
Kristin Robin Laurens, Ruth E. Roberts
Institution(s): Department of Forensic and Neurodevelopmental Sciences,Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Roberts, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Biopsychological problems / Mental health / Psychotic disorders / Brain structure and function

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194.12
Location: Arquivo PCA - Pasta 25/2012
Title:
Adolescent trajectories of fine motor and coordination skills and risk for schizophrenia
Publication year: 2020
URL:
https://www.sciencedirect.com/science/article/pii/S0920996419304293
Abstract/Results: ABSTRACT:
Premorbid motor dysfunction is one of the earliest of developmental antecedents identified among individuals who develop schizophrenia in adulthood. However, among individuals with schizophrenia, premorbid motor dysfunction is not apparent at all stages of childhood development and may reduce with increasing age. Currently, little is known about the trajectories of motor development during adolescence among youth at-risk for the disorder. One hundred and one participants were assessed repeatedly, at approximately 24-month intervals (time 1, aged 9–12 years; time 2, 11–14 years; and time 3, 13–16 years), on the Purdue Pegboard assessment, comprising four subtests: Dominant Hand (DH), Non-Dominant Hand (NDH), Both Hands (BH), and Assembly. Fine motor and coordination skills development between ages 9–16 years was compared between youth characterised by a triad of developmental antecedents of schizophrenia (ASz, N?=?32); youth with at least one affected relative with schizophrenia/schizoaffective disorder (FHx; N?=?26); and typically developing youth without antecedents or family history (TD, N?=?43). Longitudinal mixed models for repeated measures indicated significant motor skills improvements with age in TD youth on the Assembly subtest only. Relative to TD youth, we found evidence for developmental deficits (i.e., dysfunction that emerged early and remained stable) among ASz youth on DH and BH subtests, and among FHx youth on the Assembly subtest. ASz youth were characterised by a developmental delay on the Assembly subtest (i.e., initial performance decrement in middle childhood that caught up with peers’ performance during adolescence). These divergences from normative motor development may reflect differences in structural and functional neural correlates.
Accessibility: Document exists in file
Language:
eng
Author:
Dickson, H.
Secondary author(s):
Roberts, R. E., To, M., Wild, K., Loh, M., Laurens, K. R.
Document type:
Article
Number of reproductions:
1
Percentiles:
65.47|0.80
Reference:
Dickson, H., Roberts, R. E., To, M., Wild, K., Loh, M., & Laurens, K. R. (2020). Adolescent trajectories of fine motor and coordination skills and risk for schizophrenia. Schizophrenia Research, 215, 263-269. https://doi.org/10.1016/j.schres.2019.10.018
Impact Factor: 4.939|2020
Times cited: 18|2026-02-12
Indexed document: Yes
Quartile: Q1
Keywords: Psychosis / Motor development / Psychotic-like experiences / Genetic high-risk / Pegboard / Antecedents

<!-- mm occ=1 guid=[5b72d5bd5df940ab839857954d80328f] WebBehavior$=[0] -->

Adolescent trajectories of fine motor and coordination skills and risk for schizophrenia

Adolescent trajectories of fine motor and coordination skills and risk for schizophrenia
DocumentThe evolving sense of agency: Context recency and quality modulate the interaction between prospective and retrospective processes2020

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016-195
Location: BF-GMS
Title:
195 - The sense of self: A neuroimaging study of interactions between intrinsic and extrinsic self networks
Duration: 2017-04 - 2019-10
Researcher(s):
Sjoerd Ebisch, Mauro Gianni Perrucci
Institution(s): Department of Neurosciences, Imaging and Clinical Sciences, University "G. D'Annunzio" of Chieti - Pescara (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Ebisch, S.
Secondary author(s):
Perrucci, M. G.
Number of reproductions:
1
Keywords:
Intrinsic self / Extrinsic self / Brain network interactions / Neuroimaging / Psychophysiology

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016-195.05
Location: BF-GMS
Title:
The evolving sense of agency: Context recency and quality modulate the interaction between prospective and retrospective processes
Publication year: 2020
URL:
https://www.sciencedirect.com/science/article/abs/pii/S1053810020300088
Abstract/Results: ABSTRACT:
Humans acquire a sense of agency through their interactions with the world and their sensory consequences. Previous studies have highlighted stable agency-related phenomena like intentional binding, which depend on both prospective, context-dependent and retrospective, outcome-dependent processes. In the current study, we investigated the interaction between prospective and retrospective processes underlying the adaptation of an ongoing sense of agency. The results showed that prospective intentional binding developed during a temporal window of up to 20 prior events was independent of the nature of the ongoing event. By contrast, the characteristics of the ongoing event retrospectively influenced prospective intentional binding developed during a temporal window narrower than 6 prior events. These findings characterize the interaction between prospective and retrospective mechanisms as a fundamental process to continuously update the sense of agency through sensorimotor learning. High psychosis-like experience traits weakened this interaction, suggesting that reduced adaption to the context contributes to altered self-experience.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Di Plinio, S.
Secondary author(s):
Arnò, S., Perrucci, M. G., Ebisch, S. J. H.
Document type:
Article
Number of reproductions:
1
Percentiles:
53.96|0.62
Reference:
Di Plinio, S., Arnò, S., Perrucci, M. G., & Ebisch, S. J. H. (2020). The evolving sense of agency: Context recency and quality modulate the interaction between prospective and retrospective processes. Consciousness and Cognition, 80: 102903. https://doi.org/10.1016/j.concog.2020.102903
Impact Factor: 2.444|2020
Times cited: 13|2026-02-12
Indexed document: Yes
Quartile: Q3
Keywords: Intentional binding / Sense of agency / Psychosis / Sensorimotor learning / Implicit learning / Perception

<!-- mm occ=1 guid=[843d8c3795208a7e8df80d2722c5d2fb] WebBehavior$=[2] -->
DocumentThe psychology and parapsychology of spiritual emergency2021

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2018-016
Location: BF-GMS
Title:
016 - The psychology and parapsychology of spiritual emergency
Duration: 2019-06 - 2021-09
Researcher(s):
Lance Storm, Monika Goretzki
Institution(s): School of Psychology, University of Adelaide (Australia)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress Report
Final Report
Article
Language: eng
Author:
Storm, L.
Secondary author(s):
Goretzki, M.
Number of reproductions:
2
Keywords:
Imagery cultivation / Spiritual emergency / Sheep-goat effect / Spirituality / Parapsychology

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2018-016.02
Location: BF-GMS
Title:
The psychology and parapsychology of spiritual emergency
Publication year: 2021
URL:
https://www.scientificexploration.org/docs/35/jse_35_1_Storm.pdf
Abstract/Results: ABSTRACT:
A defining aspect of Spiritual Emergency (SE) is a ‘Psychic Opening’, which may predict psi performance. This study tested paranormal (psi) performance of individuals who had or were having experiences of Spiritual Emergency (i.e. ‘SE-experients’), and compared their performance against controls. The study also assessed psychological aspects of SE to differentiate it from psychosis and other proposed psi-inhibitive symptoms—namely, alogia (i.e. poverty of speech), depression, anxiety, and stress. Two groups of participants were formed: controls (mainly psychology students) and SE-experients. Participants either completed
the study on a computer in the laboratory or online. Questionnaires on Spiritual Emergency (which includes a subscale on Psychic Opening), positive symptoms of psychosis, alogia, spiritual identity, paranormal belief, mysticism, depression, anxiety, and stress, were administered to participants, who then completed the Imagery Cultivation (IC) pictureidentification psi task, which uses a shamanic-like journeying protocol (Storm & Rock, 2009a, 2009b). The differences between controls and SE-experients on the psi measures, Direct Hitting (as a percent hit-rate) and Mean Rank Scores, were not significant, but the Sum-of-Ranks difference was highly significant. Also, SE-experients had a marginally significant Mean Rank Score. Direct Hitting did not correlate significantly
with any variable, except Rank Scores, which correlated significantly with Psychic Opening, spiritual identity, and paranormal belief, and marginally significantly with Spiritual Emergency. Direct Hitting, Rank Scores, and SE did not correlate significantly with alogia, depression, anxiety, or stress, but the psychosis measure did correlate significantly with alogia, depression, anxiety, stress, and SE. The statistical evidence suggests that some proportion of SE-experients experience Psychic Opening. While SE and psychosis overlap, only SE was predicted by spiritual identity, extrovertive mysticism, and paranormal belief (but not alogia), whereas psychosis was predicted by alogia only.
Accessibility: Document exists in file
Language:
eng
Author:
Storm, L.
Secondary author(s):
Goretzki, M.
Document type:
Article
Number of reproductions:
2
Reference:
Storm, L., & Goretzki, M. (2021). The psychology and parapsychology of spiritual emergency. Journal of Scientific Exploration, 35(1), 36-64. https://doi.org/10.31275/20211889
Indexed document: No
Keywords: Imagery cultivation / Psychic ability / Psychosis / Sheep-goat effect / Spiritual emergency

<!-- mm occ=1 guid=[88145c7e85668fdc1ccd6fce2304a0f6] WebBehavior$=[0] -->

The psychology and parapsychology of spiritual emergency

The psychology and parapsychology of spiritual emergency
DocumentCoping with COVID-19: Mindfulness-based approaches for mitigating mental health crisis2021

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016-183
Location: BF-GMS
Title:
183 - Decoding the language of 'now': EEG microstates in experienced meditators, from letters to grammar
Duration: 2017-09 - 2023-09
Researcher(s):
Elena Antonova, Chrystopher Nehaniv
Institution(s): Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London (UK); University of Hertfordshire, Hatfield (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Author: Antonova, E.
Secondary author(s):
Nehaniv, C.
Number of reproductions:
3
Keywords:
Electroencephalogram (EEG) microstates / Meditation / Attention / Consciousness / Psychophysiology and Parapsychology

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2016-183.03
Location: BF-GMS
Title:
Coping with COVID-19: Mindfulness-based approaches for mitigating mental health crisis
Publication year: 2021
URL:
https://www.frontiersin.org/articles/10.3389/fpsyt.2021.563417/full
Abstract/Results: ABSTRACT:
The novel coronavirus disease COVID-19 that first emerged in Wuhan, China, in Nov-Dec 2019 has already impacted a significant proportion of the world population. Governments of many countries imposed quarantines and social distancing measures in 2020, many of which remain in place, to mitigate the spread of the SARS-Cov-2 virus causing the COVID-19 disease. The direct impact of COVID-19 on people infected with the virus, their families and the health care workers, as well as the impact of the mitigation measures such as quarantine, social distancing, and self-isolation on the rest of the population have contributed to a global mental health pandemic, including anxiety, depression, panic attacks, posttraumatic stress symptoms, psychosis, addiction, obsessive-compulsive disorder, and suicidality. These effects are present acutely (for example, due to fear of contamination or losing loved ones, effects of quarantine/isolation, withdrawal of community and social services, etc.) and may continue long after the pandemic is over (for example, due to bereavement, unemployment, financial losses, etc). The COVID-19 pandemic has triggered mental health problems in people without previous history of mental illness, as well as worsened the symptoms in those with pre-existing psychiatric diagnosis. Therefore, the global effort is called for to deal with this mental health pandemic secondary to COVID-19 itself to address the emergence of new as well as the exacerbation of the existing mental health issues. Conversely, this global context provides an extraordinary opportunity for studying individual differences in response to and resilience in the face of physical and psychological threat, challenge to “normal” way of life, and long-term uncertainty. In this viewpoint article we outline the particular suitability of mindfulness, its skills and mechanisms, as an approach to the prevention and management of mental health issues, as well as to the promotion of well-being and building the foundations of adaptability and flexibility in dealing with the long-term uncertainty and profound changes to the social, economic, and possibly political systems as this pandemic continues to unfold.
Accessibility: Document exists in file
Language:
eng
Related objects:
BL-2018-092.02
Author: Antonova, E.
Secondary author(s):
Schlosser, K., Pandey, R., Kumari, V.
Document type:
Article
Number of reproductions:
3
Percentiles:
97.30|4.25
Reference:
Antonova, E., Schlosser, K., Pandey, R., & Kumari, V. (2021). Coping with COVID-19: Mindfulness-based approaches for mitigating mental health crisis. Frontiers in Psychiatry, 12: 563417. https://doi.org/10.3389/fpsyt.2021.563417
Impact Factor: 5.435|2021
Times cited: 66|2026-02-13
Indexed document: Yes
Quartile: Q2
Keywords: COVID-19 / Mental health / Mindfulness / Depression / Anxiety / PTSD / Psychosis / Coping

<!-- mm occ=1 guid=[e81ca1ee21670a3e970e709b0fc6252b] WebBehavior$=[0] -->

Coping with COVID-19: Mindfulness-based approaches for mitigating mental health crisis

Coping with COVID-19: Mindfulness-based approaches for mitigating mental health crisis
DocumentCoping with COVID-19: Mindfulness-based approaches for mitigating mental health crisis2021

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2018-092
Location: BF-GMS
Title:
092 - Attending mindfully: A psychophysiology study of sensory processing in meditators
Duration: 2019-04 - 2024-07
Researcher(s):
Veena Kumari, Rakesh Pandey
Institution(s): Centre for Cognitive Neuroscience, Department of Life Sciences, Brunel University London, Uxbridge (UK); Department of Psychology, Banaras Hindu University, Varanasi (India)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Kumari, V.
Secondary author(s):
Pandey, R.
Number of reproductions:
3
Keywords:
Mindfulness / Sensorimotor gating / Affect-modulated startle / Response consistency / Psychophysiology and Parapsychology

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2018-092.02
Location: BF-GMS
Title:
Coping with COVID-19: Mindfulness-based approaches for mitigating mental health crisis
Publication year: 2021
URL:
https://www.frontiersin.org/articles/10.3389/fpsyt.2021.563417/full
Abstract/Results: ABSTRACT:
The novel coronavirus disease COVID-19 that first emerged in Wuhan, China, in Nov-Dec 2019 has already impacted a significant proportion of the world population. Governments of many countries imposed quarantines and social distancing measures in 2020, many of which remain in place, to mitigate the spread of the SARS-Cov-2 virus causing the COVID-19 disease. The direct impact of COVID-19 on people infected with the virus, their families and the health care workers, as well as the impact of the mitigation measures such as quarantine, social distancing, and self-isolation on the rest of the population have contributed to a global mental health pandemic, including anxiety, depression, panic attacks, posttraumatic stress symptoms, psychosis, addiction, obsessive-compulsive disorder, and suicidality. These effects are present acutely (for example, due to fear of contamination or losing loved ones, effects of quarantine/isolation, withdrawal of community and social services, etc.) and may continue long after the pandemic is over (for example, due to bereavement, unemployment, financial losses, etc). The COVID-19 pandemic has triggered mental health problems in people without previous history of mental illness, as well as worsened the symptoms in those with pre-existing psychiatric diagnosis. Therefore, the global effort is called for to deal with this mental health pandemic secondary to COVID-19 itself to address the emergence of new as well as the exacerbation of the existing mental health issues. Conversely, this global context provides an extraordinary opportunity for studying individual differences in response to and resilience in the face of physical and psychological threat, challenge to “normal” way of life, and long-term uncertainty. In this viewpoint article we outline the particular suitability of mindfulness, its skills and mechanisms, as an approach to the prevention and management of mental health issues, as well as to the promotion of well-being and building the foundations of adaptability and flexibility in dealing with the long-term uncertainty and profound changes to the social, economic, and possibly political systems as this pandemic continues to unfold.
Accessibility: Document exists in file
Language:
eng
Related objects:
BL-2016-183.03
Author: Antonova, E.
Secondary author(s):
Schlosser, K., Pandey, R., Kumari, V.
Document type:
Article-d
Number of reproductions:
3
Percentiles:
97.30|4.25
Reference:
Antonova, E., Schlosser, K., Pandey, R., & Kumari, V. (2021). Coping with COVID-19: Mindfulness-based approaches for mitigating mental health crisis. Frontiers in Psychiatry, 12: 563417. https://doi.org/10.3389/fpsyt.2021.563417
Impact Factor: 5.435|2021
Times cited: 66|2026-02-13
Indexed document: Yes
Quartile: Q2
Keywords: COVID-19 / Mental health / Mindfulness / Depression / Anxiety / PTSD / Psychosis / Coping

<!-- mm occ=1 guid=[e81ca1ee21670a3e970e709b0fc6252b] WebBehavior$=[0] -->

Coping with COVID-19: Mindfulness-based approaches for mitigating mental health crisis

Coping with COVID-19: Mindfulness-based approaches for mitigating mental health crisis
DocumentCortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: Relationship to psychosocial stress and cognition2014

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2006-035
Location: Arquivo PCA - Pasta 17/2006
Title:
035 - Development and genetic correlates of brain function in children at high- and low-risk for developing schizophrenia
Duration: 2008-01 - 2011-07
Researcher(s):
Kristin Robyn Laurens, Sheilagh Hodgins, Robin M. Murray, Eric A. Taylor, Collier, Sir Michael Rutter
Institution(s): Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
5 Articles (under review or published)
1 Book chapter
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Murray, R., Taylor, E., Collier, D., Rutter, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Assessment tools / Biopsychological problems / Mental health / Psychotic disorders

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2006-035.27
Location: Arquivo PCA - Pasta 17/2006
Title:
Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: Relationship to psychosocial stress and cognition
Publication year: 2014
URL:
https://www.sciencedirect.com/science/article/pii/S0306453014001061?via%3Dihub
Abstract/Results: ABSTRACT:
Abnormal hypothalamic-pituitary-adrenal (HPA) axis function, as indexed by elevated diurnal cortisol levels and/or a blunted cortisol awakening response (CAR), has been observed among patients with first episode psychosis and associated with neurocognitive deficits in this population. However, the extent to which these features precede illness onset is unclear. The current study aimed to determine whether children who are at putatively elevated risk for psychosis because they present multiple antecedents of schizophrenia (ASz), and high-risk children with a family history of illness (FHx), are characterized by abnormal cortisol levels when compared with their typically developing (TD) peers. A further aim was to investigate the extent to which cortisol levels are associated with psychosocial stress and neurocognitive function. Thirty-three ASz children, 22 FHx children, and 40 TD children were identified at age 9-12 years using a novel community-based screening procedure or as relatives of individuals with schizophrenia. All participants were antipsychotic-naive and not currently seeking treatment for their symptoms. At age 11-14 years, participants provided salivary cortisol samples and completed psychosocial stress measures and tests of memory and executive function. Results indicated that FHx children, but not ASz children, were characterized by a blunted CAR relative to their TD peers (effect size = -0.73, p = 0.01) that was not explained by psychosocial stress exposure or by distress relating to these experiences. Neither FHx nor ASz children were characterized by elevated diurnal cortisol. Among both FHx and ASz children, more pronounced HPA axis function abnormalities (i.e., higher diurnal cortisol levels and greater blunting of the CAR) were associated with poorer performance on tests of verbal memory and executive function. These findings support the notion that at least some HPA axis abnormalities described in psychosis precede illness onset, rather than being a subsequent epiphenomenon. We speculate that the blunted CAR may constitute an early (potentially genetically mediated) marker of psychosis vulnerability, whilst elevated diurnal cortisol levels may emerge only proximally to disease onset.
Accessibility: Documenti exists in file
Language:
eng
Author:
Cullen, A. E.
Secondary author(s):
Zunszain, P. A., Dickson, H., Roberts, R. E., Fisher, H. L., Pariante, C. M., Laurens, K. R.
Document type:
Article
Number of reproductions:
1
Percentiles:
85.90|1.66
Reference:
Cullen, A. E., Zunszain, P. A., Dickson, H., Roberts, R. E., Fisher, H. L., Pariante, C. M., & Laurens, K. R. (2014). Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: relationship to psychosocial stress and cognition. Psychoneuroendocrinology, 46(100):1-13. https://doi.org/10.1016/j.psyneuen.2014.03.010
Impact Factor: 4.944|2014
Times cited: 63|2026-02-06
Indexed document: Yes
Quartile: Q1
Keywords: Psychosis / High-risk / HPA axis / Negative life events / Hassles / Memory / Executive function / Development

<!-- mm occ=1 guid=[8b15d425f4a0762ea5009ff4b9fb2bc4] WebBehavior$=[0] -->

Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: Relationship to psychosocial stress and cognition

Cortisol awakening response and diurnal cortisol among children at elevated risk for schizophrenia: Relationship to psychosocial stress and cognition
DocumentCortisol levels in childhood associated with emergence of attenuated psychotic symptoms in early adulthood2022

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012
Location: SEC PCA
Title:
2012 Grants
Start date: 2013-02

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2012-194
Location: Arquivo PCA - Pasta 25/2012
Title:
194 - Characterising developmental trajectories of brain function from childhood into adolescence
Duration: 2013-04 - 2017-09
Researcher(s):
Kristin Robin Laurens, Ruth E. Roberts
Institution(s): Department of Forensic and Neurodevelopmental Sciences,Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress reports
Final report
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Roberts, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Biopsychological problems / Mental health / Psychotic disorders / Brain structure and function

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Reference code: PT/FB/BL-2012-194.16
Location: BF-GMS
Title:
Cortisol levels in childhood associated with emergence of attenuated psychotic symptoms in early adulthood
Publication year: 2022
URL:
https://www.sciencedirect.com/science/article/abs/pii/S0006322321015298
Abstract/Results: ABSTRACT:
BACKGROUND
In youth at clinical high-risk for psychosis, elevated cortisol levels predict subsequent onset of psychotic disorder. However, it is unclear whether cortisol alterations are evident at an earlier clinical stage and promote progression of psychosis expression. The present study aimed to address this issue by investigating whether cortisol levels in childhood were associated with the emergence of attenuated psychotic symptoms in early adulthood. In exploratory analyses, we examined whether cortisol and psychosocial stress measures interacted in predicting attenuated psychotic symptoms.
METHODS
A sample of children (N=109) enriched for psychosis risk factors were recruited at age 9-12 years and assessed at age 11-14 years (T1) and 17-21 years (T2). Measures of psychopathology, psychosocial stressors, and salivary cortisol were obtained at T1. Attenuated psychotic symptoms were assessed at T2 using the Prodromal Questionnaire (PQ).
RESULTS
Diurnal cortisol (ß = 0.915, 95% CI: 0.062, 1.769) and daily stressors (ß = 0.379, 95% CI: 0.034, 0.723) at T1 were independently associated with total PQ scores at T2 after accounting for demographic factors and prior psychopathology. Exploratory analyses indicated a significant interaction between diurnal cortisol and daily stressors (ß = 0.743, 95% CI: 0.081, 1.405), with the highest predicted T2 total PQ scores occurring when both diurnal cortisol and daily stressors were increased.
CONCLUSIONS
Our findings suggest that daily stressors and elevations in diurnal cortisol in late childhood/early adolescence increases risk for developing attenuated psychotic symptoms. These findings emphasise the importance of assessing environmental and biological risk factors for psychosis during neurodevelopmentally vulnerable time-periods.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
BL-2006-035.28
Author: Cullen, A.
Secondary author(s):
Fisher, H., Gullett, N., Fraser, E., Roberts, R. E., Zahid, U., To, M., Yap, N., Zunszain, P., Pariante, C., Wood, S., McGuire, P., Murray, R., Mondelli, V., Laurens, K. R.
Document type:
Article
Number of reproductions:
1
Percentiles:
80.86|1.39
Reference:
Cullen, A., Fisher, H., Gullett, N., Fraser, E., Roberts, R. E., Zahid, U., To, M., Yap, N., Zunszain, P., Pariante, C., Wood, S., McGuire, P., Murray, R., Mondelli, V., & Laurens, K. R. (2022). Cortisol levels in childhood associated with emergence of attenuated psychotic symptoms in early adulthood. Biological psychiatry, 91(2), 226-235. https://doi.org/10.1016/j.biopsych.2021.08.009
Impact Factor: 10.600|2022
Times cited: 23|2026-02-13
Indexed document: Yes
Quartile: Q1
Keywords: Schizophrenia / Psychosis / HPA axis / Salivary cortisol / Stress / Adversity

<!-- mm occ=1 guid=[beb30100fb049e33afb20061984030e2] WebBehavior$=[3] -->
DocumentCortisol levels in childhood associated with emergence of attenuated psychotic symptoms in early adulthood2022

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Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2006-035
Location: Arquivo PCA - Pasta 17/2006
Title:
035 - Development and genetic correlates of brain function in children at high- and low-risk for developing schizophrenia
Duration: 2008-01 - 2011-07
Researcher(s):
Kristin Robyn Laurens, Sheilagh Hodgins, Robin M. Murray, Eric A. Taylor, Collier, Sir Michael Rutter
Institution(s): Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
5 Articles (under review or published)
1 Book chapter
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Murray, R., Taylor, E., Collier, D., Rutter, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Assessment tools / Biopsychological problems / Mental health / Psychotic disorders

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2006-035.28
Location: BF-GMS
Title:
Cortisol levels in childhood associated with emergence of attenuated psychotic symptoms in early adulthood
Publication year: 2022
URL:
https://www.sciencedirect.com/science/article/abs/pii/S0006322321015298
Abstract/Results: ABSTRACT:
BACKGROUND
In youth at clinical high-risk for psychosis, elevated cortisol levels predict subsequent onset of psychotic disorder. However, it is unclear whether cortisol alterations are evident at an earlier clinical stage and promote progression of psychosis expression. The present study aimed to address this issue by investigating whether cortisol levels in childhood were associated with the emergence of attenuated psychotic symptoms in early adulthood. In exploratory analyses, we examined whether cortisol and psychosocial stress measures interacted in predicting attenuated psychotic symptoms.
METHODS
A sample of children (N=109) enriched for psychosis risk factors were recruited at age 9-12 years and assessed at age 11-14 years (T1) and 17-21 years (T2). Measures of psychopathology, psychosocial stressors, and salivary cortisol were obtained at T1. Attenuated psychotic symptoms were assessed at T2 using the Prodromal Questionnaire (PQ).
RESULTS
Diurnal cortisol (ß = 0.915, 95% CI: 0.062, 1.769) and daily stressors (ß = 0.379, 95% CI: 0.034, 0.723) at T1 were independently associated with total PQ scores at T2 after accounting for demographic factors and prior psychopathology. Exploratory analyses indicated a significant interaction between diurnal cortisol and daily stressors (ß = 0.743, 95% CI: 0.081, 1.405), with the highest predicted T2 total PQ scores occurring when both diurnal cortisol and daily stressors were increased.
CONCLUSIONS
Our findings suggest that daily stressors and elevations in diurnal cortisol in late childhood/early adolescence increases risk for developing attenuated psychotic symptoms. These findings emphasise the importance of assessing environmental and biological risk factors for psychosis during neurodevelopmentally vulnerable time-periods.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Related objects:
BL-2012-194.16
Author: Cullen, A.
Secondary author(s):
Fisher, H., Gullett, N., Fraser, E., Roberts, R. E., Zahid, U., To, M., Yap, N., Zunszain, P., Pariante, C., Wood, S., McGuire, P., Murray, R., Mondelli, V., Laurens, K. R.
Document type:
Article-d
Number of reproductions:
1
Percentiles:
80.86|1.39
Reference:
Cullen, A., Fisher, H., Gullett, N., Fraser, E., Roberts, R. E., Zahid, U., To, M., Yap, N., Zunszain, P., Pariante, C., Wood, S., McGuire, P., Murray, R., Mondelli, V., & Laurens, K. R. (2022). Cortisol levels in childhood associated with emergence of attenuated psychotic symptoms in early adulthood. Biological psychiatry, 91(2), 226-235. https://doi.org/10.1016/j.biopsych.2021.08.009
Impact Factor: 10.600|2022
Times cited: 23|2026-02-13
Indexed document: Yes
Quartile: Q1
Keywords: Schizophrenia / Psychosis / HPA axis / Salivary cortisol / Stress / Adversity

<!-- mm occ=1 guid=[3ba9a7b024827428b689a8ed116c3b7a] WebBehavior$=[3] -->
DocumentDissociable impairments of verbal learning differentiate childhood risk profiles for schizophrenia2022

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2006
Location: Arquivo PCA - Pastas 1 a 22 /2006
Title:
2006 Grants
Start date: 2007-01 - 2013-11
Dimension/support:
22 caixas de arquivo

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2006-035
Location: Arquivo PCA - Pasta 17/2006
Title:
035 - Development and genetic correlates of brain function in children at high- and low-risk for developing schizophrenia
Duration: 2008-01 - 2011-07
Researcher(s):
Kristin Robyn Laurens, Sheilagh Hodgins, Robin M. Murray, Eric A. Taylor, Collier, Sir Michael Rutter
Institution(s): Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
5 Articles (under review or published)
1 Book chapter
Language: eng
Author:
Laurens, K. R.
Secondary author(s):
Hodgins, S., Murray, R., Taylor, E., Collier, D., Rutter, M.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Assessment tools / Biopsychological problems / Mental health / Psychotic disorders

<!-- vis-dbg web=[web] Visitor=[2] base=[fbial] -->
Reference code: PT/FB/BL-2006-035.33
Location: BF-GMS
Title:
Dissociable impairments of verbal learning differentiate childhood risk profiles for schizophrenia
Publication year: 2022
URL:
https://www.sciencedirect.com/science/article/pii/S221500132200004X
Abstract/Results: Abstract
Poor verbal learning and memory function is well-documented among individuals with schizophrenia and those at clinical high-risk for psychosis. This study aimed to identify these impairments among children aged 9–12 years with different schizophrenia risk profiles (family history or antecedents of schizophrenia, each of higher[H] or lower[L] risk load) relative to typically developing peers. These three groups were recruited via community-screening, and differentiated for analysis into: typically developing children (TD = 45); children who had 1 first- or =2 second-degree affected relatives (FHxH = 16) or one second-degree relative (FHxL = 15); and children presenting multiple replicated antecedents of schizophrenia whose clinical symptoms persisted at 2- and/or 4-year follow-up (ASzH = 16) or remitted during follow-up (ASzL = 16). Verbal learning/memory measures assessed at baseline (age 9–12 years) included: (i) total recall; (ii) trial 1 recall; (iii) learning score; (iv) intrusions; (v) total words lost; and (vi) serial position patterns. Analyses of variance indicated that FHxH and ASzH youth demonstrated impaired total recall compared to TD and ASzL children and lost significantly more words between trials than TD and FHxL children. Learning score was impaired among both FHxH and FHxL relative to TD and ASzL children. Thus, among putatively at-risk children, total words recalled and lost distinguished those with higher risk load (by family history or persistent antecedent symptomology), whereas learning score indexed familial vulnerability. Follow-up of the sample is needed to determine the capacity of verbal learning deficits to predict later illness and provide a potential avenue for early remediation to improve clinical or functional outcomes.
Accessibility: Document exists in file
Copyright/Reproduction:
by permission
Language:
eng
Author:
Carpendale, E. J.
Secondary author(s):
Cullen, A. E., Dickson, H., Laurens, K. R.
Document type:
Article
Number of reproductions:
1
Percentiles:
25.31|0.31
Reference:
Carpendale, E. J., Cullen, A. E., Dickson, H., & Laurens, K. R. (2022) Dissociable impairments of verbal learning differentiate childhood risk profiles for schizophrenia. Schizophrenia Research: Cognition, 28, 100239. https://doi.org/10.1016/j.scog.2022.100239
Impact Factor: 2.800|2022
Times cited: 4|2026-02-13
Indexed document: Yes
Quartile: Q3
Keywords: Psychosis / Genetic liability / Memory / Cognition / High-risk